■自1990年代以来,腹腔镜肾部分切除术(LPN)仍然是治疗局部肾细胞癌(RCC)的最常用措施,其发病率越来越高。本研究旨在确定影响LPN术后引流时间和总引流量的危险因素。
■2012年1月至2022年12月在我院接受LPN的612例RCC患者的临床资料,包括术后引流时间和总引流量,进行回顾性分析。采用单变量和多变量线性回归和相关性分析来确定21个因素之间的相关性。其中包括性别,年龄,饮酒史,RCC家族史,体重,体重指数(BMI),和操作时间,术后引流时间,和总排水量。
■平均引流时间为3.52±0.71天(范围:2至8天),平均总引流量为259.83±72.64mL(范围:50至620mL)。单变量和多变量线性回归分析均显示出几个具有统计学意义的关联。性别(p=0.04),年龄(p=0.008),吸烟史(p<0.001),糖尿病(p=0.032),运行时间(p=0.014),和BMI(p=0.023)被确定为与引流时间相关的重要因素。另一方面,年龄(p=0.008),吸烟史(p<0.001),糖尿病(p=0.006),BMI(p=0.016)是影响总引流量的独立危险因素。
■发现术后引流的持续时间与性别有关,年龄,吸烟史,糖尿病,操作时间,BMI。相比之下,总排水量主要受年龄影响,吸烟史,糖尿病,LPN后BMI较高。对于患有这些疾病的患者,围手术期注意止血和控制出血至关重要。
UNASSIGNED: Laparoscopic partial nephrectomy (LPN) remains the most commonly used measure for treating localized renal cell cancer (RCC) with an increasing incidence of RCC ever since the 1990s. This study aimed to identify risk factors that affect the postoperative time of drainage and total drainage volume after LPN.
UNASSIGNED: The clinical data of 612 RCC patients who received LPN from January 2012 to December 2022 in our hospital, including the postoperative drainage time and total drainage volume, were retrospectively analyzed. Univariable and multivariable linear regression and correlation analyses were used to identify the correlations between 21 factors, which include gender, age, history of alcohol consumption, family history of RCC, body weight, body mass index (BMI), and operation time, postoperative drainage time, and total drainage volume.
UNASSIGNED: The mean time of drainage was 3.52 ± 0.71 days (range: 2 to 8 days), with an average total drainage volume of 259.83 ± 72.64 mL (range: 50 to 620 mL). Both univariable and multivariable linear regression analyses revealed several statistically significant associations. Gender (p = 0.04), age (p = 0.008), smoking history (p < 0.001), diabetes (p = 0.032), operation time (p = 0.014), and BMI (p = 0.023) were identified as significant factors associated with the time of drainage. On the other hand, age (p = 0.008), smoking history (p < 0.001), diabetes (p = 0.006), and BMI (p = 0.016) emerged as independent risk factors influencing the total drainage volume.
UNASSIGNED: The duration of postoperative drainage was found to be associated with gender, age, smoking history, diabetes, operation time, and BMI. In contrast, the total drainage volume was primarily influenced by age, smoking history, diabetes, and high BMI following LPN. For patients with these conditions, meticulous attention to hemostasis and bleeding control is crucial during the perioperative period.