背景:由皮肤病引起的面部瑕疵对患者的自尊和生活质量(QOL)有显著影响。
目的:评估矫正化妆品(CC)对皮肤质量参数的QOL的影响。
方法:对具有可见面部瑕疵的受试者进行了一项国际观察性研究,这些研究将受益于矫正化妆品。调查人员收集了有关人口统计的数据,QOL使用Skindex-16量表,皮肤干燥和紧绷,受试者和研究者满意度,基线和每日使用4至6周后的化妆品可接受性和耐受性。
结果:共有1840名受试者参加;平均年龄为31.5±11.1,95%为女性。痤疮占皮肤状况的48.9%,其次是黄褐斑(16.7%)和酒渣鼻(15.3%)。在81.2%的受试者中,至少有10%的面部受到影响,并且45.3%的受试者将该状况评为毁容;45.0%和44.4%,分别,基线时皮肤既不拉紧也不干燥。基线Skindex-16症状评分,情感,功能和总体功能分别为1.4±1.3、3.5±1.6、2.4±1.8和2.4±1.3,从0到6。依从性为96.0±10.6%。在研究结束时,Skindex-16评分对所有参数都有显著改善(p<0.0001),皮肤干燥和紧绷。受试者和研究者满意度高或非常高;化妆品可接受性高或非常高,局部耐受性好或非常好。
结论:经过测试的矫正化妆品显着改善了面部有明显缺陷的受试者的生活质量,皮肤紧绷和干燥,并被很好地容忍。
BACKGROUND: Facial blemishes resulting from skin disorders have a significant effect on the patient\'s self-esteem and impact quality of life (QOL).
OBJECTIVE: To assess the impact of a corrective cosmetic (CC) on QOL on top of skin quality parameters.
METHODS: An international observational study was conducted on subjects with visible facial flaws that would benefit from a corrective cosmetic. Investigators collected data regarding demographics, QOL using the Skindex-16 scale, skin dryness and tautness, subject and investigator satisfaction, cosmetic acceptability and tolerance at baseline and after 4 to 6 weeks of daily use.
RESULTS: A total of 1840 subjects participated; the mean age was 31.5±11.1 and 95% were women. Acne accounted for 48.9% of skin conditions, followed by melasma (16.7%) and rosacea (15.3%). Of the subjects 81.2% had at least 10% of the face affected and the condition was rated as disfiguring by 45.3% of the subjects; 45.0% and 44.4%, respectively, had neither taut nor dry skin at baseline. Baseline Skindex-16 scores for symptoms, emotions, functioning and overall were 1.4±1.3, 3.5±1.6, 2.4±1.8 and 2.4±1.3, respectively, on a scale from 0 to 6. Compliance was 96.0±10.6%. At the end of the study, Skindex-16 scores had significantly (p<0.0001) improved for all parameters, as did skin dryness and tautness. Subject and investigator satisfaction were high or very high; cosmetic acceptability was high or very high and local tolerance good or very good.
CONCLUSIONS: The tested corrective cosmetic significantly improved the QOL of subjects with significant facial flaws, skin tautness and dryness, and was well tolerated.