卵巢类固醇细胞瘤很少见,占所有卵巢肿瘤的0.1%以下。在多毛症的无数原因中,卵巢肿瘤占报告病例的1%。我们介绍了一名49岁的绝经后妇女因多毛症寻求医疗护理2年的情况。此病例说明了绝经后患者的罕见卵巢病理学与多毛症的临床表现之间的异常和有趣的联系。她的超声检查和MRI显示右附件肿块,实囊性粘连,并伴有薄薄的隔膜。她的实验室检查显示高水平的总睾酮为256ng/ml(8.4-48.1ng/ml),游离睾酮为7.36pg/ml(0.2-4.1pg/ml),而DHEAS-234µg/dl(35.4-256µg/dl)和CA125-15.8U/L(0.0-35U/L)在正常范围内。她接受了剖腹探查术,进行了全腹子宫切除术和卵巢切除术。组织病理学检查和免疫组织化学最终确定了类固醇细胞肿瘤的存在,具体分类为“未指定”(NOS),在右卵巢。
Ovarian steroid cell tumors are rare, representing less than 0.1% of all ovarian neoplasms. Among the myriad causes of hirsutism, ovarian tumors account for 1% of the reported cases. We present the case of a 49-year-old parous postmenopausal woman who sought medical attention for hirsutism for 2 years. This case illustrates the unusual and interesting connection between rare ovarian pathology and the clinical manifestation of hirsutism in a postmenopausal patient. Her ultrasonography and MRI showed a right adnexal mass of solid-cystic consistency with thin septations. Her laboratory workup revealed high levels of total testosterone of 256 ng/ml (8.4-48.1ng/ml) and free testosterone of 7.36 pg/ml (0.2-4.1 pg/ml), while DHEAS - 234 µg/dl (35.4-256 µg/dl) and CA125 - 15.8U/L (0.0-35 U/L) were in the normal range. She underwent exploratory laparotomy with a total abdominal hysterectomy and oophorectomy. Histopathological examination and immunohistochemistry conclusively established the presence of a steroid cell tumor, specifically classified as \"Not Otherwise Specified\"(NOS), in the right ovary.