Severe mental illness

严重精神疾病
  • 文章类型: Journal Article
    断言外展(AO)是一种系统的方法,用于吸引患有严重精神疾病的脆弱患者。
    本综述旨在对与AO模型原理相关的参与策略进行全面分析,以阐明AO的有效组成部分,更好地理解AO背景下的参与,并考虑包含变革机制。
    从1806年到2022年12月完成了系统的混合方法审查(没有预先注册)。使用JBI量表对符合纳入标准的文章进行方法学质量评级,并使用元聚合方法进行主题综合。根据系统评价和荟萃分析(PRISMA)声明的首选报告项目进行报告。
    18篇文章符合入选标准。文献由三个主要主题定义:参与的定义和观点;AO与参与有关的关键原则;以及增强参与的其他原则和战略。
    尽管定义参与存在异质性,AO专业人员和患者之间的关系在参与过程中至关重要.随后,AO的四项关键原则成为促进参与的核心。最后,我们确定了一些被认为在AO参与过程中至关重要的额外原则.该综述最后对未来的研究和AO在常规临床护理中的实施提出了建议。
    本审查的报告遵循PRISMA指南进行,未在PROSPERO注册,因为已完成的审查无法注册。
    UNASSIGNED: Assertive outreach (AO) is a systematic approach to engage vulnerable patients with serious mental illness.
    UNASSIGNED: This review aims to provide a comprehensive analysis of engagement strategies in relation to principles of the AO model to clarify effective components of AO, better understand engagement in an AO context, and consider encompassing change mechanisms.
    UNASSIGNED: A systematic mixed-methods review was completed from 1806 to December 2022 (no pre-registration). Articles meeting the inclusion criteria were rated for methodological quality using the JBI scales and thematic synthesis using a meta-aggregative approach. Reporting was according to the Preferred Reporting Items for Systematic Review and Meta-Analysis (PRISMA) statement.
    UNASSIGNED: Eighteen articles met the inclusion criteria. The literature was defined by three main themes: definition and perspectives of engagement; key principles of AO in relation to engagement; and additional principles and strategies enhancing engagement.
    UNASSIGNED: Despite the heterogeneity in defining engagement, the relationship between AO professionals and patients emerged as crucial in the process of engagement. Subsequently, the four key principles of AO emerged as central to promoting engagement. Finally, we identified a number of additional principles that are considered crucial in the engagement process in AO. The review concludes with recommendations for future research and the implementation of AO in routine clinical care.
    The reporting of this review is conducted following the PRISMA guidance and not registered at PROSPERO because completed reviews cannot be registered.
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  • 文章类型: Journal Article
    目的:人类视觉系统通过抑制对与周围环境相似的纹理的反应来简化视觉处理。精神分裂症(ISZ)患者的环绕抑制较弱;视觉空间上下文的这种改变使用可能与他们经历的特征性视觉扭曲有关。
    方法:为了了解精神病精神病理学中的非典型周围抑制,我们调查了ISZ的神经生理反应,健康对照(HC),双相情感障碍(IBP)患者,和一级亲属(ISZR/IBPR)。参与者对环形环绕的圆形目标进行对比判断任务,并发脑电图。根据对具有正交周围的中心目标的响应来估计与方向无关的(未调整的)抑制;通过将指数函数拟合到抑制的增加来估计抑制的方向依赖性,因为周围变得与中心更加对齐。
    结果:ISZ表现出减弱的未调谐抑制以及增强的方向依赖性抑制。N1视觉诱发电位与抑制的方向依赖性相关,ISZ和ISZR(但不是IBP或IBPR)显示N1的定向依赖性增强。在定向条件下崩溃,ISZ的N1缺乏对右半球的不对称性;N1不对称性的减少与未调谐抑制的减少有关,现实世界的感知异常,和精神病精神病理学。在ISZ和IBP中N1的整体振幅降低。
    结论:ISZ症状学的关键指标与未调节抑制的减少相关。在N1VEP中反映了ISZ对抑制周围相对方向的灵敏度提高,这通常与更高级别的视觉功能相关联,例如空间注意力的分配或场景分割。
    OBJECTIVE: The human visual system streamlines visual processing by suppressing responses to textures that are similar to their surrounding context. Surround suppression is weaker in individuals with schizophrenia (ISZ); this altered use of visuospatial context may relate to the characteristic visual distortions they experience.
    METHODS: To understand atypical surround suppression in psychotic psychopathology, we investigated neurophysiological responses in ISZ, healthy controls (HC), individuals with bipolar disorder (IBP), and first-degree relatives (ISZR/IBPR). Participants performed a contrast judgment task on a circular target with annular surrounds, with concurrent electroencephalography. Orientation-independent (untuned) suppression was estimated from responses to central targets with orthogonal surrounds; the orientation-dependence of suppression was estimated by fitting an exponential function to the increase in suppression as surrounds became more aligned with the center.
    RESULTS: ISZ exhibited weakened untuned suppression coupled with enhanced orientation-dependence of suppression. The N1 visual evoked potential was associated with the orientation-dependence of suppression, with ISZ and ISZR (but not IBP or IBPR) showing enhanced orientation-dependence of the N1. Collapsed across orientation conditions, the N1 for ISZ lacked asymmetry toward the right hemisphere; this reduction in N1 asymmetry was associated with reduced untuned suppression, real-world perceptual anomalies, and psychotic psychopathology. The overall amplitude of the N1 was reduced in ISZ and IBP.
    CONCLUSIONS: Key measures of symptomatology for ISZ are associated with reductions in untuned suppression. Increased sensitivity for ISZ to the relative orientation of suppressive surrounds is reflected in the N1 VEP, which is commonly associated with higher-level visual functions such as allocation of spatial attention or scene segmentation.
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  • 文章类型: Journal Article
    媒体中对精神分裂症的负面描述可以提示病情的污名化。然而,因为关于语言污名化精神分裂症的研究集中在纸质媒体上,其结果对当代媒体的推广性有限。此外,关于指导媒体专业人员准确描述精神分裂症的干预措施的研究一直很少。本研究有两个目的:(1)评估印刷,Web,瑞典的广播/电视新闻媒体描绘了精神分裂症,(2)评估针对媒体专业人士对精神分裂症信息的反应以及污名化语言的后果。
    使用Retriever\的数据库中的数据,考虑到媒体类型和主题,术语“精神分裂症”和“精神分裂症”在过去的20年中进行了研究,而对这些术语的污名化报道的分析使用了过去10年的媒体。还评估了媒体专业人士在反污名化信息运动SigmaWatch中的反应和行动。
    在2002年至2022年之间,“精神分裂症”在数据集中被提及34141次,“精神分裂症”被提及10058次。然而,无统计学显著趋势.所有媒体主题和大多数类型的媒体都包含污名化的报道。在收到StigmaWatch信息电子邮件的230名媒体专业人士中,77(33%)回答。大多数回答都是支持性的,14%的专业人员报告采取了纠正措施(例如,修改对精神分裂症的错误描述)。
    没有媒体话题没有语言污名化精神分裂症。反污名宣传运动似乎很有效,对于大多数回应的媒体专业人士来说,他们是支持的,相当比例的人报告采取了纠正措施。
    UNASSIGNED: Negative portrayals of schizophrenia in media can prompt the condition\'s stigmatization. However, because research on language stigmatizing schizophrenia has focused on paper-based media, its results have limited generalizability to contemporary media. Also, research on interventions to guide media professionals in accurately depicting schizophrenia has been scarce. The present study had two aims: (1) to assess how print, web, and radio/TV news media in Sweden portray schizophrenia and (2) to evaluate a campaign targeting media professionals\' responses to information about schizophrenia and the consequences of stigmatizing language.
    UNASSIGNED: Using data from Retriever\'s database, considering media types and topics, the terms \"schizophrenia\" and \"schizophrenic\" were examined in the past 20 years, whereas analyses of stigmatizing reporting of these terms used media from the past 10 years. Media professionals\' responses and actions in the anti-stigma information campaign StigmaWatch were also evaluated.
    UNASSIGNED: Between 2002 and 2022, \"schizophrenia\" was mentioned 34 141 times in the dataset and \"schizophrenic\" 10 058 times. However, no trends were statistically significant. All media topics and most types of media contained stigmatizing reporting. Of the 230 media professionals who received informative emails from StigmaWatch, 77 (33%) responded. Most responses were supportive, and 14% of the professionals reported taking corrective measures (eg, revising erroneous descriptions of schizophrenia) following the email.
    UNASSIGNED: No media topic was free of language stigmatizing schizophrenia. The anti-stigma information campaign seemed to have been effective, for most media professionals who responded were supportive, and a sizable proportion reported taking corrective measures.
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  • 文章类型: Journal Article
    背景:精神疾病患者所经历的身体健康合并症和过早死亡导致了作为医院精神卫生服务标准护理一部分的运动服务的增加。尽管患有精神疾病的人获得锻炼服务的机会有所增加,目前缺乏对运动疗法患者进行评估和分诊的指南.
    目的:为在基于医院的精神保健中从事运动服务的患者制定运动前筛查和健康评估指南,并建立用于基于医院的精神保健的运动疗法分诊框架。
    方法:使用由两个在线调查和两轮焦点小组讨论组成的Delphi技术来获得多学科专家小组的共识。
    结果:在运动前健康筛查方面达成共识,健康领域评估,代表高价值临床评估的评估工具,以及运动疗法中运动疗法分类框架的创建和拟议利用。
    结论:这项研究是首次在澳大利亚医院的精神卫生保健中提供运动疗法实施指导。结果为运动疗法患者的适当健康评估和筛查提供了建议,并通过逐步框架为患者实施和分诊运动疗法提供指导,以确定(a)运动疗法所需的及时性和(b)提供运动疗法所需的支持水平。
    BACKGROUND: The physical health comorbidities and premature mortality experienced by people with mental illness has led to an increase in exercise services embedded as part of standard care in hospital-based mental health services. Despite the increase in access to exercise services for people experiencing mental illness, there is currently a lack of guidelines on the assessment and triage of patients into exercise therapy.
    OBJECTIVE: To develop guidelines for the pre-exercise screening and health assessment of patients engaged with exercise services in hospital-based mental healthcare and to establish an exercise therapy triage framework for use in hospital-based mental healthcare.
    METHODS: A Delphi technique consisting of two online surveys and two rounds of focus group discussions was used to gain consensus from a multidisciplinary panel of experts.
    RESULTS: Consensus was reached on aspects of pre-exercise health screening, health domain assessment, assessment tools representing high-value clinical assessment, and the creation and proposed utilisation of an exercise therapy triage framework within exercise therapy.
    CONCLUSIONS: This study is the first of its kind to provide guidance on the implementation of exercise therapy within Australian hospital-based mental healthcare. The results provide recommendations for appropriate health assessment and screening of patients in exercise therapy, and provide guidance on the implementation and triage of patients into exercise therapy via a stepped framework to determine (a) the timeliness of exercise therapy required and (b) the level of support required in the delivery of their exercise therapy.
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  • 文章类型: Journal Article
    背景:众所周知,不坚持服用精神药物对患者和社会都有有害后果。
    目的:收集有关不依从发生率的信息,以及影响重度和持续性精神障碍患者坚持精神药物治疗的因素和原因。
    方法:对过去五年(2015-2020年)在PubMed等专业数据库上发表的有关成年患者(>17岁)的科学文章进行了系统回顾,Scopus,Scielo和BioMed.来自索引期刊的影响因子>0.5的原始文章,英文或西班牙文,通过分析,prospective,回顾性,纳入横断面和随机设计.一旦确定了物品,对它们进行了分析,提取回答研究问题所需的信息。
    结果:共15篇。其中,40%(n=6)在2020年发表,20%(n=3)在中国生产,53.3%(n=8)具有观察性设计。共纳入5,837名患者,其中50.6%是男性(n=2955),在10项调查中报告了中等依从性(n=10;66.7%)。不依从性从7.7%到60.6%不等。影响依从性的因素是患者特有的(年龄和性别),他们的家庭支持网络,与疾病或治疗有关。不坚持的主要原因是缺乏洞察力。
    结论:精神药物治疗的依从性是多因素的。应改善获得精神卫生服务的机会,重点放在病人教育和提供更多的精神疾病知识。促进教育和与精神科医生互动的干预措施可能是有益的。
    BACKGROUND: It is known that non-adherence to psychiatric medications has harmful consequences for both patients and society.
    OBJECTIVE: To collect information on the incidence of non-adherence, and the factors and causes affecting adherence to psychopharmacological treatment in patients with severe and persistent mental disorders.
    METHODS: A systematic review of scientific articles on adult patients (>17 years) published in the last five years (2015-2020) on specialised databases such as PubMed, Scopus, Scielo and BioMed. Original articles from indexed journals with an impact factor >0.5, in English or Spanish, with an analytical, prospective, retrospective, cross-sectional and randomised design were included. Once the articles were identified, they were analysed, extracting the information necessary to answer the research questions.
    RESULTS: Fifteen articles were included. Of these, 40% (n = 6) were published in 2020, 20% (n = 3) were produced in China and 53.3% (n = 8) had an observational design. A total of 5,837 patients were included, of which 50.6% were men (n = 2,955), with moderate adherence (n = 10; 66.7%) reported in 10 investigations. Non-adherence varies from 7.7% to 60.6%. The factors that affect adherence are specific to the patient (age and sex), their family support network, and related to the disease or the treatment. The main cause of non-adherence is lack of insight.
    CONCLUSIONS: Adherence to treatment with psychotropic drugs is multifactorial. Access to mental health services should be improved, with an emphasis placed on patient education and providing greater knowledge of mental illness. Interventions to promote education and interaction with the psychiatrist could be beneficial.
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  • 文章类型: Journal Article
    背景:精神分裂症患者减重手术(BS)的结果知之甚少。我们旨在分析BS对精神分裂症(SZ)或分裂情感障碍(SZA)患者的影响。
    方法:这是一个多中心,在西班牙7家公立转诊医院接受BS治疗的SZ或SZA患者的回顾性病例对照研究.以1:4的比例选择没有精神病合并症的对照。术前以及BS后12、24、36、48和60个月收集详细的临床和生化数据。
    结果:研究了20例SZ(n=15;75%)或SZA(n=5;25%)患者和80个匹配的对照。关于总体重减轻百分比的演变,患者和对照组之间没有差异。除高血压外,两组主要合并症的缓解率相似,从第3年开始,患有精神病的患者的比例较低。两组在手术后30天内均无死亡。精神病药物负担在随访期间没有变化。
    结论:BS在精心选择的SZ患者中是安全有效的。精神疾病的病程似乎并未因手术而恶化。
    BACKGROUND: Outcomes of bariatric surgery (BS) in patients with schizophrenia are poorly understood. We aimed to analyze the effects of BS in patients with schizophrenia (SZ) or schizoaffective disorder (SZA).
    METHODS: This was a multicenter, retrospective case-control study in patients with SZ or SZA who had undergone BS in seven public referral hospitals in Spain. Controls without psychiatric comorbidity were selected in a 1:4 ratio. Detailed clinical and biochemical data were collected preoperatively and at 12, 24, 36, 48, and 60 months after BS.
    RESULTS: Twenty patients with SZ (n = 15; 75%) or SZA (n = 5; 25%) and 80 matched controls were studied. There were no differences between patients and controls concerning the evolution of the percentage of total weight loss. The remission rate of the main comorbidities was similar between groups except for hypertension, which was lower in patients with a psychotic disorder from year 3. There were no mortalities within 30 days of surgery in either group. The psychiatric medication burden did not change during follow-up.
    CONCLUSIONS: BS is safe and effective in carefully selected patients with SZ. The course of the psychiatric disease does not seem to be worsened by the procedure.
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  • 文章类型: Journal Article
    对精神分裂症谱系障碍的污名普遍存在,并对服务的获取和交付产生负面影响。与精神分裂症相关的认知障碍(CIAS)很常见,但它与污名的关联是未知的。在这项研究中,作者研究了接受认知矫正治疗的CIAS患者是否报告了CIAS相关的病耻感,并试图在CIAS相关的病耻感和康复相关结局之间建立关联.
    来自48名精神分裂症谱系诊断个体的数据来自一项评估认知修复的更大研究。参与者完成了CIAS相关污名的测量,内化的精神疾病耻辱,自我感知认知障碍,认知表现,和面试官评定的生活质量。
    CIAS相关的污名被普遍报道,并且与内在化的污名和自我感知的认知障碍显著正相关。CIAS相关的污名也与从事目标导向行为和日常活动的动机显着负相关。
    与CIAS相关的污名存在,并需要对精神病服务提供的影响进行进一步的探索。
    UNASSIGNED: Stigma toward schizophrenia spectrum disorders is pervasive and negatively influences service access and delivery. Cognitive impairment associated with schizophrenia (CIAS) is common, but its association with stigma is unknown. In this study, the authors examined whether individuals with CIAS receiving cognitive remediation treatment report experiencing CIAS-related stigma and sought to establish associations between CIAS-related stigma and recovery-relevant outcomes.
    UNASSIGNED: Data from 48 individuals with schizophrenia spectrum diagnoses were drawn from a larger study evaluating cognitive remediation. Participants completed measures of CIAS-related stigma, internalized mental illness stigma, self-perceived cognitive impairment, cognitive performance, and interviewer-rated quality of life.
    UNASSIGNED: CIAS-related stigma was commonly reported and significantly positively associated with internalized stigma and self-perceived cognitive impairment. CIAS-related stigma was also significantly negatively associated with motivation to engage in goal-directed behavior and daily activities.
    UNASSIGNED: CIAS-related stigma exists and warrants additional exploration with regard to implications for psychiatric service delivery.
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  • 文章类型: Editorial
    患有严重精神疾病和怀孕的妇女在获得精神和围产期健康护理方面遭受巨大困难。患有精神分裂症等精神病的妇女面临更高的怀孕和产后并发症的风险。同样,缺乏获得整体精神护理的机会给这些妇女及其子女带来了特别的危险。需要为这些准妈妈及其婴儿提供量身定制的护理,以预防和改善健康并发症,心理和身体。这将需要有针对性地资助将妇女与护理联系起来并提供连续性护理的服务。
    Women with severe mental illness and pregnancy suffer substantial travails in accessing care for mental and perinatal health. Women with psychotic illnesses such as schizophrenia face higher risks of pregnancy and postnatal complications. Similarly, lack of access to holistic psychiatric care presents particular perils for these women and their children. Tailored care for these mothers-to-be and their babies is needed to prevent and ameliorate health complications, mental and physical. This will require targeted funding of services that connect women with and provide continuity of care.
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  • 文章类型: Journal Article
    目标:探讨是否:(i)患有严重精神疾病(SMI)的人的口腔健康状况比普通人群差,(ii)SMI患者口腔健康不良的危险因素。
    方法:横断面数据来自国家健康和营养调查(1999-2016),包括自我评估的口腔健康,口腔疼痛,牙齿脱落,牙周炎阶段,和腐烂的数量,失踪,和填充的牙齿。口腔健康不良的候选危险因素包括人口统计学特征,生活方式因素,身体健康合并症,和牙齿卫生行为。序数逻辑回归和零膨胀负二项模型用于探索口腔健康结果的预测因素。
    结果:分析共53,348例,包括718人与SMI。在完全调整的模型中,SMI患者更有可能出现牙齿脱落(OR1.60,95%CI:1.34-1.92).在有SMI的人中,确定的不良口腔健康结果的危险因素是年龄较大,白人种族,收入较低,吸烟史,和糖尿病。参与体育锻炼和日常使用牙线与更好的口腔健康结果相关。
    结论:SMI患者的牙齿脱落率高于一般人群,某些亚组尤其处于危险之中。定期进行体育锻炼和使用牙线可能会降低口腔健康不良的风险,而吸烟和糖尿病可能会增加风险。这些发现表明,有针对性的预防和早期干预策略可以减轻SMI患者的不良口腔健康结果。
    OBJECTIVE: To explore whether: (i) people with severe mental illness (SMI) experience worse oral health than the general population, and (ii) the risk factors for poor oral health in people with SMI.
    METHODS: Cross-sectional data were extracted from the National Health and Nutrition Examination Survey (1999-2016), including on self-rated oral health, oral pain, tooth loss, periodontitis stage, and number of decayed, missing, and filled teeth. Candidate risk factors for poor oral health included demographic characteristics, lifestyle factors, physical health comorbidities, and dental hygiene behaviours. Ordinal logistic regression and zero-inflated negative binomial models were used to explore predictors of oral health outcomes.
    RESULTS: There were 53,348 cases included in the analysis, including 718 people with SMI. In the fully adjusted model, people with SMI were more likely to suffer from tooth loss (OR 1.60, 95% CI: 1.34-1.92). In people with SMI, risk factors identified for poor oral health outcomes were older age, white ethnicity, lower income, smoking history, and diabetes. Engaging in physical activity and daily use of dental floss were associated with better oral health outcomes.
    CONCLUSIONS: People with SMI experience higher rates of tooth loss than the general population, and certain subgroups are particularly at risk. Performing regular physical exercise and flossing may lower the risk of poor oral health, while smoking and diabetes may increase the risk. These findings suggest opportunities for targeted prevention and early intervention strategies to mitigate adverse oral health outcomes in people with SMI.
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  • 文章类型: Journal Article
    与美国(US)的许多种族和族裔群体相比,南亚人(SAs)对精神卫生服务的利用不足,然而,关于严重精神疾病(SMI)患者的经验的研究有限。这项研究检查了患有SMI诊断的SA患者的精神病医疗保健经验(例如,严重的抑郁症,双相情感障碍,精神分裂症)在纽约市。数据收集包括对36名参与者(21名患者,11个家庭成员,4名临床医生)。数据在NVivo中管理。两对SA研究人员进行了主题分析。由于对帮助的感知需求较低,有限的心理健康知识导致对SAs的延迟护理。易于访问,语言资源,患者-提供者关系,和家庭参与影响精神病医疗经验。处方药物,自我激励,通信,和宗教习俗是帮助症状管理和恢复的因素。研究结果强调,有必要改善SA社区的精神病医疗服务和文化上突出的心理健康教育。
    South Asians (SAs) underutilize mental health services compared to many racial and ethnic groups in the United States (US), yet there is limited research on the experiences of SAs living with severe mental illness (SMI). This study examined psychiatric healthcare experiences of SA patients with SMI diagnoses (e.g., severe depression, bipolar disorder, schizophrenia) in New York City. Data collection included semi-structured interviews with 36 participants (21 patients, 11 family members, 4 clinicians). Data was managed in NVivo. Two pairs of SA researchers conducted thematic analysis. Limited mental health knowledge led to delayed care for SAs due to a low perceived need for help. Ease of access, linguistic resources, patient-provider relationships, and family involvement influenced psychiatric healthcare experiences. Prescribed medications, self-motivation, communication, and religious practices were factors aiding symptom management and recovery. Findings highlight the need for improving psychiatric healthcare access and culturally-salient mental health education for SA communities.
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