UNASSIGNED:设置准确性在肿瘤的局部控制中起着极其重要的作用。这项研究的目的是验证“球面掩模”光学定位系统(S-M_OPS)快速准确设置的可行性。
UNASSIGNED:从2016年到2021年,我们使用S-M_OPS监督了1981年患者的15441个部分(患有颅内癌,鼻咽部,食道,肺,肝脏,腹部或子宫颈)接受调强放射治疗(IMRT),并记录了配准时间、遮罩变形等数据。然后,我们使用了S-M_OPS,激光线和锥形束计算机断层扫描(CBCT)共设置277个分数,并以CBCT引导设置结果为标准,记录激光线引导设置误差和S-M_OPS引导设置误差。
UNASSIGNED:S-M_OPS监督结果:激光线引导设置的平均时间为31.75s。12.8%的参考点的平均偏差大于2mm,5.2%的参考点的平均偏差大于3mm。共同设置结果:S-M_OPS引导设置的平均时间为7.47s,CBCT引导设置的平均时间为228.84s(包括CBCT扫描和人工验证的时间).在LAT(左/右),VRT(上/下)和LNG(前/后)方向,激光线引导设置误差(平均值±SD)为-0.21±3.13mm,分别为1.02±2.76mm和2.22±4.26mm;激光线引导设置误差的95%置信区间(95%CIs)为-6.35~5.93mm,-4.39至6.43mm和-6.14至10.58mm;S-M_OPS引导设置误差为0.12±1.91mm,1.02±1.81mm和-0.10±2.25mm;S-M_OPS引导设置误差的95%CI为-3.86~3.62mm,-2.53至4.57mm和-4.51至4.31mm。
UNASSIGNED:与激光线引导设置相比,S-M_OPS可以大大提高设置精度和稳定性。此外,S-M_OPS可以在更短的设置时间内提供与CBCT相当的设置精度。
UNASSIGNED: The setup accuracy plays an extremely important role in the local control of tumors. The purpose of this study is to verify the feasibility of \"Sphere-Mask\" Optical Positioning System (S-M_OPS) for fast and accurate
setup.
UNASSIGNED: From 2016 to 2021, we used S-M_OPS to supervise 15441 fractions in 1981patients (with the cancer in intracalvarium, nasopharynx, esophagus, lung, liver, abdomen or cervix) undergoing intensity-modulated radiation therapy (IMRT), and recorded the data such as registration time and mask deformation. Then, we used S-M_OPS, laser line and cone beam computed tomography (CBCT) for co-setup in 277 fractions, and recorded laser line-guided
setup errors and S-M_OPS-guided
setup errors with CBCT-guided
setup result as the standard.
UNASSIGNED: S-M_OPS supervision results: The average time for laser line-guided setup was 31.75s. 12.8% of the reference points had an average deviation of more than 2 mm and 5.2% of the reference points had an average deviation of more than 3 mm. Co-
setup results: The average time for S-M_OPS-guided
setup was 7.47s, and average time for CBCT-guided
setup was 228.84s (including time for CBCT scan and manual verification). In the LAT (left/right), VRT (superior/inferior) and LNG (anterior/posterior) directions, laser line-guided setup errors (mean±SD) were -0.21±3.13mm, 1.02±2.76mm and 2.22±4.26mm respectively; the 95% confidence intervals (95% CIs) of laser line-guided setup errors were -6.35 to 5.93mm, -4.39 to 6.43mm and -6.14 to 10.58mm respectively; S-M_OPS-guided setup errors were 0.12±1.91mm, 1.02±1.81mm and -0.10±2.25mm respectively; the 95% CIs of S-M_OPS-guided setup errors were -3.86 to 3.62mm, -2.53 to 4.57mm and -4.51 to 4.31mm respectively.
UNASSIGNED: S-M_OPS can greatly improve setup accuracy and stability compared with laser line-guided
setup. Furthermore, S-M_OPS can provide comparable
setup accuracy to CBCT in less
setup time.