背景:源自透明隔的中枢神经系统淋巴瘤(CNSL)非常罕见,呈现独特的诊断和治疗复杂性。本病例报告旨在阐明诊断挑战,治疗策略,以及这种罕见表现的结果。通过记录这个案子,我们寻求增进医学界的理解,并为CNSL的管理贡献宝贵的见解,特别是在非典型的地方。
方法:一名45岁女性出现持续性头痛,视力模糊,和运动无力,促使一个彻底的神经学评估。影像学显示透明隔肿块增强,导致CNSL的诊断。患者的担忧不仅包括身体症状,还包括诊断和治疗过程中的情绪影响。
方法:CNSL的诊断确认涉及脑脊液分析和影像学发现,突出区分淋巴瘤与其他颅内病变的挑战。该病例强调了在罕见的CNSL演示文稿中进行全面诊断评估的重要性。
方法:多学科管理包括大剂量甲氨蝶呤化疗和糖皮质激素,考虑神经外科干预。心理社会支持和自我护理策略被纳入治疗计划,以满足患者的整体需求。
结果:监测显示治疗反应积极,在透明隔肿块中观察到减少。定期评估确保坚持干预措施和治疗相关副作用的管理,有助于有利的结果和改善患者的生活质量。
结论:本案例强调了细致的诊断评估和个性化治疗方法在管理罕见的CNSL表现中的重要性。专家之间的合作和全面的患者支持对于优化结果和解决CNSL在独特解剖位置带来的多方面挑战至关重要。
BACKGROUND: Central nervous system lymphoma (CNSL) originating from the septum pellucidum is exceptionally rare, presenting unique diagnostic and therapeutic complexities. This case report aims to elucidate the diagnostic challenges, treatment strategies, and outcomes of this rare manifestation. By documenting this case, we seek to enhance understanding within the medical community and contribute valuable insights to the management of CNSL, particularly in atypical locations.
METHODS: A 45-year-old female presented with persistent headaches, blurred vision, and motor weakness, prompting a thorough neurological evaluation. Imaging revealed an enhancing mass in the septum pellucidum, leading to the diagnosis of CNSL. The patient\'s concerns encompassed not only the physical symptoms but also the emotional impact of her diagnosis and treatment journey.
METHODS: Diagnostic confirmation of CNSL involved cerebrospinal fluid analysis and imaging findings, highlighting the challenge of distinguishing lymphoma from other intracranial pathologies. The case underscores the importance of comprehensive diagnostic evaluation in rare CNSL presentations.
METHODS: Multidisciplinary management included high-dose methotrexate-based chemotherapy and corticosteroids, with consideration for neurosurgical intervention. Psychosocial support and self-care strategies were integrated into the treatment plan to address holistic patient needs.
RESULTS: Monitoring revealed a positive treatment response, with a reduction observed in the septum pellucidum mass. Regular assessments ensured adherence to interventions and management of treatment-related side effects, contributing to favorable outcomes and improved quality of life for the patient.
CONCLUSIONS: This case emphasizes the significance of meticulous diagnostic evaluation and personalized treatment approaches in managing rare CNSL presentations. Collaboration among specialists and comprehensive patient support is paramount in optimizing outcomes and addressing the multifaceted challenges posed by CNSL in unique anatomical locations.