目的:先前评估鼻腔鼻窦解剖变异与复发性急性鼻-鼻窦炎(RARS)的作用的研究因结果不一致而受到限制。这项研究的目的是评估鼻窦解剖变异与RARS之间的关联。
方法:使用2020年8月至2023年1月到鼻科诊所就诊的患者进行了1:2回顾性病例对照研究。将总共60例RARS患者与120例对照患者进行了比较。根据过敏和鼻学国际共识声明标准诊断RARS,每年有4次或更多次急性鼻-鼻窦炎独立发作,客观发现至少有一次发作。完全解决了发作之间的感染。鼻窦解剖变异包括鼻中隔偏曲(NSD),大疱性外耳(CB),眶下(Haller)细胞,中鼻道的鼻中隔骨刺,和额窦细胞(超agger,前倾,和额叶上细胞)。
结果:RARS和对照组患者的年龄相似(47.4±16.5vs.49.3±14.5,p=0.432)。RARS组和对照组都更可能是女性(78.3%vs.77.5%,p=0.899)。与对照组相比,NSD和RARS之间没有显着关联(OR=0.97,p=0.916),并且任何解剖变异与RARS之间没有显着关联[眶下细胞(OR=0.64,p=0.167),CB(OR=0.84,p=0.596),中鼻道骨刺(OR=1.28,p=0.514),超agger(OR=0.88,p=0.708),前额叶细胞(OR=0.97,p=0.939),或额上细胞(OR=1.13,p=0.766)]。
结论:我们的研究结果表明鼻中隔偏曲或所研究的任何解剖变异与RARS之间没有关联。
方法:3喉镜,2024.
OBJECTIVE: Prior studies evaluating the role of sinonasal anatomic variants with recurrent acute rhinosinusitis (RARS) are limited by inconsistent results. The goal of this study is to evaluate the association between sinonasal anatomic variants and RARS.
METHODS: A 1:2 retrospective case-control study was conducted using patients presenting to the rhinology clinic from August 2020 to January 2023. A total of 60 patients with RARS were compared to 120 control patients. RARS was diagnosed based on the International Consensus Statement on Allergy and Rhinology criteria of four or more independent episodes of acute rhinosinusitis per year with at least one episode documented by objective findings, with complete resolution of the infection in-between episodes. Sinonasal anatomic variants included nasal septal deviation (NSD), concha bullosa (CB), infraorbital (Haller) cells, nasal septal spur in the middle meatus, and frontal sinus cells (supra-agger, supra-agger frontal, and suprabullar frontal cells).
RESULTS: Age was similar in RARS and control patients (47.4 ± 16.5 vs. 49.3 ± 14.5, p = 0.432). Both the RARS group and control group were more likely to be female (78.3% vs. 77.5%, p = 0.899). There was no significant association between NSD and RARS compared to the control group (OR = 0.97, p = 0.916), and no significant association between any of the anatomic variants and RARS [infraorbital cells (OR = 0.64, p = 0.167), CB (OR = 0.84, p = 0.596), spur in the middle meatus (OR = 1.28, p = 0.514), supra-agger (OR = 0.88, p = 0.708), supra-agger frontal cells (OR = 0.97, p = 0.939), or suprabullar frontal cells (OR = 1.13, p = 0.766)].
CONCLUSIONS: Our findings suggest no association between nasal septal deviation or any of the anatomic variants studied and RARS.
METHODS: 3 Laryngoscope, 134:3489-3492, 2024.