Selective embolization

  • 文章类型: Case Reports
    背景:肛门直肠血管瘤是一种罕见且经常误诊的下胃肠道(GI)出血原因。这里,我们提出了一种选择性栓塞的微创疗法。
    方法:一名21岁男性患者从小经历无痛性直肠出血,并接受溃疡性结肠炎治疗。后来的诊断研究揭示了血管病变-肛门直肠血管瘤的特定特征。直肠出血的严重程度导致有症状的贫血,可能的手术治疗与粪便失禁的高风险相关。这里,我们提出了选择性栓塞,一种微创治疗方法,被证明是一种替代治疗方法的选择。患者暂时明显改善,并有小的缺血性溃疡,用对照结肠镜治愈,没有狭窄。
    结论:了解胃肠道血管瘤的临床和放射学特征可能有助于改善诊断并避免不适当的治疗程序。
    BACKGROUND: Anorectal hemangioma is a rare and frequently misdiagnosed cause of lower gastrointestinal (GI) bleeding. Here, we present a minimally invasive therapy with selective embolization.
    METHODS: A 21-year-old male patient experienced painless rectal bleeding since childhood and was treated for ulcerative colitis. Diagnostic studies later revealed specific characteristics for vascular lesions-anorectal hemangiomas. The severity of rectal bleeding caused symptomatic anemia and possible surgical treatment was associated with a high risk of fecal incontinence. Here, we present selective embolization, a minimally invasive therapeutic approach that is proven as an alternative therapeutic method of choice. The patient significantly improved temporarily and had a small ischemic ulcer, which healed with a control colonoscopy and developed no stenosis.
    CONCLUSIONS: Awareness of the clinical and radiological features of GI hemangiomas may help improve diagnostics and avoid inappropriate therapeutic procedures.
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  • 文章类型: Journal Article
    虽然部分肾切除术提供肿瘤疗效并保留T1肾肿瘤的肾功能,肾动脉假性动脉瘤(RAP)仍然是一种罕见但可能危及生命的并发症.这项研究比较了机器人辅助(RAPN)的RAP发生率,腹腔镜(LPN),大型三级肿瘤中心的开放性(OPN)部分肾切除术。这项回顾性研究分析了2012年至2022年间785例接受肾部分切除术的患者(398RAPN,122LPN,265OPN)。数据包括人口统计,肿瘤大小/位置,手术类型,临床表现,治疗,和术后结果。主要结果是RAP发生率,次要结果包括演示,治疗功效,和肾功能。17名患者(2.1%)发生了RAP,表现为大量血尿(100%),失血性休克(5.8%),和凝块保留(23%)。中位发病时间为术后12天。RAP发生在4(1%),4(3.3%),和9例(3.4%)患者在RAPN后,LPN,OPN,分别(p=0.04)。只有手术长度和手术方式与RAP独立相关。选择性栓塞术后即刻出血控制达94%,一名患者需要第二次栓塞。不需要额外的手术或肾切除术。两组在一年时估计的GFR相似(p=0.53)。与LPN和OPN相比,RAPN的RAP发生率明显较低(p=0.04)。急诊血管造影栓塞被证明是有效的,对肾功能无长期影响。这项回顾性研究缺乏随机化和长期随访。有必要对更大的数据集和更长的随访进行进一步的研究。这项研究表明,与传统方法相比,机器人辅助肾部分切除术与RAP的风险显着降低相关。急诊栓塞可有效治疗RAP,而不会损害长期肾功能。
    While partial nephrectomy offers oncologic efficacy and preserves renal function for T1 renal tumors, renal artery pseudoaneurysm (RAP) remains a rare but potentially life-threatening complication. This study compared RAP incidence across robotic-assisted (RAPN), laparoscopic (LPN), and open (OPN) partial nephrectomies in a large tertiary oncological center. This retrospective study analyzed 785 patients undergoing partial nephrectomy between 2012 and 2022 (398 RAPN, 122 LPN, 265 OPN). Data included demographics, tumor size/location, surgical type, clinical presentation, treatment, and post-operative outcomes. The primary outcome was RAP incidence, with secondary outcomes including presentation, treatment efficacy, and renal function. Seventeen patients (2.1%) developed RAP, presenting with massive hematuria (100%), hemorrhagic shock (5.8%), and clot retention (23%). The median onset was 12 days postoperatively. RAP occurred in 4 (1%), 4 (3.3%), and 9 (3.4%) patients following RAPN, LPN, and OPN, respectively (p = 0.04). Only operative length and surgical approach were independently associated with RAP. Selective embolization achieved immediate bleeding control in 94%, with one patient requiring a second embolization. No additional surgery or nephrectomy was needed. Estimated GFR at one year was similar across both groups (p = 0.53). RAPN demonstrated a significantly lower RAP incidence compared to LPN and OPN (p = 0.04). Emergency angiographic embolization proved effective, with no long-term renal function impact. This retrospective study lacked randomization and long-term follow-up. Further research with larger datasets and longer follow-ups is warranted. This study suggests that robotic-assisted partial nephrectomy is associated with a significantly lower risk of RAP compared to traditional approaches. Emergency embolization effectively treats RAP without compromising long-term renal function.
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  • 文章类型: Case Reports
    血管平滑肌脂肪瘤是伴有脂肪的良性肾错构瘤,平滑肌,和异常血管(曲折,变形)组件。出血的风险与肿瘤的大小有关,动脉瘤的存在,与结节性硬化症有关。在本病例报告中,我们回顾了一名42岁女性的病例,该女性表现为急性侧腹疼痛和血红蛋白减少,CT诊断为AML伴右肾动脉假性动脉瘤。随后成功地完成了饲喂血管的线圈栓塞和使用PVA颗粒。选择性栓塞仍然是一种微创,有吸引力的选择,和保留肾单位的方法。
    Angiomyolipomas are benign renal hamartomas with - fat, smooth muscle, and abnormal blood vessel (tortuous, dysmorphic) components. The risk of hemorrhage is related to size of the tumor, presence of aneurysm, associations with tuberous sclerosis. In this case report we review the case of a 42-year-old woman presenting with acute flank pain and decreased hemoglobin, who was diagnosed with AML with right renal artery pseudo aneurysm on CT. Subsequent coil embolization of feeding vessels and using PVA particles was successfully done. Selective embolization remains a minimally invasive, attractive option, and a nephron sparing approach.
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  • 文章类型: Case Reports
    背景:纵隔血管瘤罕见,其病因仍不清楚。大多数患者没有病理性临床症状,诊断通常是偶然的。由于关于这种疾病的管理的现有文献很少,治疗的选择和时机仍存在争议.
    方法:这里,我们报告了一例66岁女性的奇静脉弓血管瘤,该患者表现为呼吸困难,胸部不适,吞咽困难,和减肥。同时发现了保守治疗难以治疗的右乳糜胸。对肿块进行了CT引导活检,它证实了病变的血管性质。因此,患者接受了血管造影,然后进行血管内栓塞.三天后,胸腔镜手术切除肿块和修复乳糜漏是安全的。病人在术后第七天顺利出院,完全解决了所有出现的症状。
    结论:有症状的纵隔血管瘤的治疗可能是强制性的,但是对这些罕见的畸形采取全面的多学科方法是必不可少的。尽管存在术中出血的风险,选择性血管内栓塞,然后进行胸腔镜手术,可以实现完整安全的切除,效果良好.
    BACKGROUND: Mediastinal hemangiomas are rare, and their etiology remains unclear. Most patients affected have no pathognomonic clinical symptoms, and the diagnosis is often incidental. Due to the paucity of the available literature regarding the management of this disease, the choice and timing of treatment remains controversial.
    METHODS: Herein, we report the case of a hemangioma of the azygos vein arch in a 66-year-old woman who presented with dyspnea, chest discomfort, dysphagia, and weight loss. A simultaneous right chylothorax refractory to conservative management was found. A CT-guided biopsy of the mass was performed, and it confirmed the vascular nature of the lesion. Therefore, the patient underwent an angiography followed by endo-vascular embolization. Three days later, thoracoscopic surgical resection of the mass and the repair of the chyle leakage were performed safely. The patient was discharged uneventfully on postoperative day seven, with complete resolution of all the presenting symptoms.
    CONCLUSIONS: Treatment of symptomatic mediastinal hemangiomas could be mandatory, but a thorough multidisciplinary approach to these rare malformations is essential. Despite the risk of intraoperative bleeding, selective endovascular embolization followed by thoracoscopic surgery allowed for a complete and safe resection with a good outcome.
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  • 文章类型: Case Reports
    直肌鞘血肿,这主要是由于腹部创伤或抗凝血剂的使用,可能是具有挑战性的,延迟诊断可能导致低血容量性休克甚至死亡。在这项研究中,我们的目的是介绍一例在住院并接受2019年冠状病毒病(COVID-19)治疗的患者中出现的直肌鞘血肿的治疗.一名70岁的女性患者因呼吸衰竭而被送往重症监护病房(ICU),并突然出现心动过速和低血压。然后,该患者被诊断为直肌鞘血肿,并在确保血流动力学稳定后,接受了血管造影栓塞治疗。治疗后,患者保持血流动力学稳定,对照计算机断层扫描(CT)显示血肿消退.直肌鞘血肿特别是伴有其他合并症或积极的手术干预可能导致早期高死亡率。还应该记住,在COVID-19大流行期间,在过去的两年里影响了世界,直肌鞘血肿可能是突发性低血压和腹胀的根本原因,不应忘记,在无法实现血流动力学稳定的情况下,由经验丰富的介入放射科医师进行血管造影栓塞是治疗的主要手段。
    A rectus sheath hematoma, which is mostly encountered due to abdominal traumas or anticoagulant use, can be challenging, and a delayed diagnosis may lead to hypovolemic shock and even death. In this study, we aimed to present the management of a case of rectus sheath hematoma that developed in a patient who was hospitalized and under coronavirus disease 2019 (COVID-19) treatment. A 70-year-old female patient was admitted to the intensive care unit (ICU) due to respiratory failure and developed a sudden onset of tachycardia and hypotension. The patient was then diagnosed with a rectus sheath hematoma and after ensuring hemodynamic stability she was treated with angiographic embolization. Following the treatment, the patient remained hemodynamically stable and a control computed tomography (CT) revealed regression in the hematoma. Rectus sheath hematomas especially accompanied by additional comorbidities or aggressive surgical interventions may result in high mortality rates in the early period. It should also be kept in mind that during the COVID-19 pandemic, which has affected the world in the last two years, rectus sheath hematomas may be the underlying cause of sudden hypotension and abdominal distension, and it should not be forgotten that angiographic embolization performed by experienced interventional radiologists is the mainstay of treatment in cases where hemodynamic stability can\'t be achieved.
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  • 文章类型: English Abstract
    OBJECTIVE: To improve treatment outcomes in victims with kidney damage following blunt and stab abdominal trauma by using of minimally invasive methods of diagnosis and treatment.
    METHODS: About 1.2-3.5% of all victims arrived to the Dzhanelidze St. Petersburg Research Institute for Emergency Care have kidney injuries. We analyzed the results of treatment of 117 patients with isolated and combined blunt and stab abdominal injuries. The retrospective (2014-2017) group included 62 victims, and the prospective (2018-2021) group enrolled 55 patients who were treated according to the new algorithm. This algorithm included non-surgical and minimally invasive management for patients with systolic blood pressure >90 mm Hg after contrast-enhanced CT. Angiography with selective embolization was required for ongoing bleeding. We analyzed incidence of open interventions, organ-sparing procedures, complications, duration of treatment and mortality. Between-group differences were assessed using the χ2 test and Student\'s test.
    RESULTS: In both groups, kidney damage in most victims with abdominal trauma was due to road accident and catatrauma. Most patients had combined abdominal injuries, mainly in combination with head and chest lesions. Severity of injuries and clinical condition were similar in both groups. In the retrospective group, there were 9 laparotomies with nephrectomy. Nephrorraphy was performed in 8 cases, kidney vessel suture - in 4 patietns. In the prospective group, nephrectomy was performed in 3 patients with unstable hemodynamics and injuries AAST grade V. Nephrorraphy was performed in 4 victims. In one case, vascular suture was applied for tangential vein damage. All laparoscopies in both groups were diagnostic without nephrectomy. We used non-surgical treatment in 34 patients of the prospective group. One patient underwent angiography and selective embolization of renal artery branches. There were no significant between-group differences in the incidence of infectious and non-infectious complications. Mortality rate was 30.6% (n=19) and 27.3% (n=15) in the retrospective and prospective groups, respectively.
    CONCLUSIONS: The proposed algorithm for kidney injury made it possible to reduce the incidence of laparoscopies and laparotomies by 2 times, preserve the damaged kidney in 94.5% of cases and avoid invasive treatment in 62% of victims.
    UNASSIGNED: Оценка и улучшение результатов лечения пострадавших с повреждением почек путем применения высокотехнологичных малоинвазивных методов диагностики и консервативного лечения.
    UNASSIGNED: Ежегодно в травмоцентр I уровня СПб НИИ скорой помощи имени И.И. Джанелидзе с повреждением почки поступает 1,2—3,5% всех пострадавших. Проведен анализ результатов лечения 117 пациентов с повреждениями почек при сочетанных и изолированных травмах и ранениях живота, находившихся на лечении в травмоцентре I уровня. В ретроспективную (2014—2017 гг.) группу вошли 62 пострадавших, в проспективную (2018—2021 гг.) — 55 пациентов, которым лечение проводили в соответствии с новым алгоритмом. Последний включал проведение консервативного и малоинвазивного лечения при стабильной гемодинамике после проведения МСКТ. При выявлении признаков продолжающегося кровотечения выполняли ангиографию с селективной ангиоэмболизацией. Сравнивали результаты лечения по частоте открытых оперативных вмешательств, применения органосохраняющих методов лечения, осложнений, продолжительности лечения и уровня летальности. Степень достоверности различий показателей рассчитывали по критерию χ2 и критерию Стьюдента.
    UNASSIGNED: В обеих группах большинство пострадавших с повреждением почки при травме живота поступили в травмоцентр после дорожно-транспортных происшествий и кататравм. У большинства пациентов были сочетанные повреждения живота, преимущественно в сочетании с травмами головы и груди. Статистически значимых различий тяжести травмы по шкалам AIS, ISS, Ю.Н. Цибина, ВПХ-П и ВПХ-П(Р), тяжести состояния (ВПХ-СП) не выявлено. В ретроспективной группе нефрэктомию выполнили в 9 случаях во время лапаротомий вне зависимости от показателей гемодинамики и состояния пострадавших. Ушивание повреждений почки выполнено у 8 пострадавших, шов сосудов почек — у 4. В проспективной группе почка удалена при ее повреждении V степени в 3 случаях при нестабильной гемодинамике. Ушиты повреждения почки у 4 пострадавших. В одном случае при краевом ранении почечной вены наложен сосудистый шов. Все видеолапароскопии в обеих группах носили диагностический характер и произведены без удаления почек. Тактика неоперативного лечения применена у 34 пострадавших проспективной группы. Ангиография и селективная эмболизация ветвей почечной артерии выполнены одному пациенту. Статистически значимых различий между группами по частоте инфекционных и неинфекционных осложнений не выявлено. В ретроспективной группе умерли 19 (30,6%) пострадавших, в проспективной — 15 (27,3%).
    UNASSIGNED: Использование предложенного лечебно-диагностического алгоритма при травме почек позволило в 2 раза снизить частоту видеолапароскопий и лапаротомий, в 94,5% случаях сохранить поврежденную почку и избежать проведения инвазивных методов лечения у 62% пострадавших.
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  • 文章类型: Journal Article
    一些出版物表明,超选择性常规经动脉化疗栓塞(cTACE),意味着使用尽可能靠近肿瘤的微导管选择性地进行cTACE,改善结果,最大限度地发挥抗肿瘤作用,最大限度地减少周围肝实质的附带损害。来自欧洲肝脏研究协会(EASL)和欧洲医学肿瘤学会(ESMO)的最新建议强调,TACE必须用于肝细胞癌(HCC)“选择性靶向”和超选择性导管插入术。“手稿的目标是更好地定义这种人群,并标准化超选择性cTACE(ss-cTACE)技术。在TACE方面具有丰富临床程序经验的专家小组,在一个虚拟会议上聚集在一起,提出建议并表达他们的共识。专家建议在任何时候提出cTACE,它应该是ss-cTACE,优选使用1.5-2.0Fr微导管。理想情况下,SS-cTACE应推荐给少于5个病变且最多涉及2个节段的患者,最大肿瘤小于5厘米。血管造影锥形束计算机断层扫描(CBCT)应用于检测增强肿瘤,肿瘤喂食器和引导肿瘤靶向。应覆盖整个肿瘤体积以获得最佳反应。鼓励增加肿瘤周边缘,但不是强制性的。处理应该包括油包水乳液,其质量可通过“跌落测试”进行评估。“应该系统地进行额外的颗粒栓塞,根据cTACE程序的定义。非对比CBCT或多探测器计算机断层扫描(MDCT)结合血管造影被认为是TACE成像的金标准。并应用于评估手术期间的肿瘤覆盖率。专家认为,超选择性降低了不良反应的发生率并提高了耐受性。专家建议使用对比增强计算机断层扫描(CT)作为ss-cTACE后首次随访的初始成像,和磁共振成像(MRI),如果剩余的肿瘤活力不能在CT上自信地评估。如果在六个月内两次ss-cTACE会议后未获得任何响应,患者必须被认为不适合接受TACE治疗,并建议接受替代治疗.患者最好通过多学科决策来服务,介入放射科医生应该在病人选择中发挥积极作用,治疗分配,和术后护理。
    Several publications show that superselective conventional TransArterial ChemoEmbolization (cTACE), meaning cTACE performed selectively with a microcatheter positioned as close as possible to the tumor, improves outcomes, maximizing the anti-tumoral effect and minimizing the collateral damages of the surrounding liver parenchyma. Recent recommendations coming from the European Association for the Study of the Liver (EASL) and European Society of Medical Oncology (ESMO) highlighted that TACE must be used in Hepatocellular Carcinoma (HCC) \"selectively targetable\" and \"accessible to supraselective catheterization.\" The goal of the manuscript is to better define such population and to standardize superselective cTACE (ss-cTACE) technique. An expert panel with extensive clinical-procedural experience in TACE, have come together in a virtual meeting to generate recommendations and express their consensus. Experts recommend that anytime cTACE is proposed, it should be ss-cTACE, preferably with a 1.5-2.0 Fr microcatheter. Ideally, ss-cTACE should be proposed to patients with less than five lesions and a maximum number of two segments involved, with largest tumor smaller than 5 cm. Angio Cone-Beam Computed Tomography (CBCT) should be used to detect enhancing tumors, tumor feeders and guide tumor targeting. Whole tumor volume should be covered to obtain the best response. Adding peritumoral margins is encouraged but not mandatory. The treatment should involve a water-in-oil emulsion, whose quality is assessable with the \"drop test.\" Additional particulate embolization should be systematically performed, as per definition of cTACE procedure. Non-contrast CBCT or Multi-Detector Computed Tomography (MDCT) combined with angiography has been considered the gold standard for imaging during TACE, and should be used to assess tumor coverage during the procedure. Experts convene that superselectivity decreases incidence of adverse effects and improves tolerance. Experts recommend contrast-enhanced Computed Tomography (CT) as initial imaging on first follow-up after ss-cTACE, and Magnetic Resonance Imaging (MRI) if remaining tumor viability cannot be confidently assessed on CT. If no response is obtained after two ss-cTACE sessions within six months, patient must be considered unsuitable for TACE and proposed for alternative therapy. Patients are best served by multidisciplinary decision-making, and Interventional Radiologists should take an active role in patient selection, treatment allocation, and post-procedural care.
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  • 文章类型: Case Reports
    真深股动脉动脉瘤是人体血管系统的罕见异常,约占所有外周动脉动脉瘤的0.13%。我们报告了一名66岁的男子,患有股动脉瘤破裂和搏动性血肿。该患者接受了动脉瘤供应动脉的紧急血管内栓塞。然后,4天后,与残余血肿有关,这给病人带来了严重的不适,此外,由于血肿区域发生脓毒症并发症的风险很高,决定进行开放性动脉瘤切除术和股深动脉结扎术。
    深股动脉瘤(由血管壁薄弱引起的血管隆起)是人体血管系统的罕见异常。动脉瘤破裂会导致严重的健康问题,如出血,失血性休克甚至死亡。我们报告了一名66岁的男子,患有股动脉瘤破裂。患者接受了供应动脉瘤的动脉的紧急血管内堵塞。然后,4天后,与残余血肿有关,这给病人带来了严重的不适,而且由于并发症的高风险,决定对动脉瘤进行开放手术切除。术后时间和2年随访顺利。
    True deep femoral artery aneurysms are a rare abnormality of the human vascular system and account for approximately 0.13% of all peripheral arterial aneurysms. We report a 66-year-old man with a ruptured deep femoral artery aneurysm and a pulsating hematoma. The patient underwent urgent endovascular embolization of the aneurysm-supplying artery. Then, 4 days later, in connection with the residual hematoma, which caused severe discomfort to the patient, and also due to the high risk of septic complications in the area of the hematoma, it was decided to perform an open aneurysmectomy and deep femoral artery ligation.
    A deep femoral artery aneurysm (a bulge in a blood vessel caused by a weakness in the blood vessel wall) is a rare abnormality of the human vascular system. A ruptured aneurysm can cause serious health problems such as bleeding, hemorrhagic shock and even death. We report a 66-year-old man with a ruptured femoral artery aneurysm. The patient underwent urgent intravascular plugging of the artery supplying the aneurysm. Then, 4 days later, in connection with the residual hematoma, which caused severe discomfort to the patient, and also due to the high risk of complications, it was decided to perform an open operative excision of the aneurysm. The postoperative period and 2-year follow-up were uneventful.
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  • 文章类型: Case Reports
    我们报告了一名14岁男子的病例,该男子因创伤性左动脉窦瘘而受到高流量阴茎异常勃起的影响而到达急诊科。经过临床检查,对阴茎进行彩色多普勒超声检查,显示左动脉窦瘘7×16×30mm,高速和湍流。瘘管通过三次高选择性血管内栓塞治疗成功,随访20天,临床检查结果正常。
    We report the case of a 14-year-old man who arrived at the emergency department affected by a high-flow priapism due to a traumatic left arterial-sinusoidal fistula. After clinical examination, a colour Doppler ultrasound of the penis was performed which showed a left arterial-sinusoidal fistula measuring 7×16×30mm, with high-speed and turbulent flow. The fistula was successfully treated by three highly selective endovascular embolizations and at the 20days follow-up, clinical examination resulted normal.
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  • 文章类型: Case Reports
    肾移植活检后动静脉瘘(AVF)的发展是一种罕见的并发症,在大多数情况下,它与自发解决有关。然而,在某些情况下需要介入治疗,以防止移植物丢失。选择性栓塞已被描述为替代治疗。在本研究中,我们描述了我们对肾移植患者活检后AVF的经验,采用选择性栓塞治疗。从2005年到2015年,共进行了452例肾移植活检,12患有需要栓塞的AVF。在92%的案例中,这是成功的。事先,平均血清肌酐水平为2.45mg/dL,手术后,然而,这一数字增加到3.05,3个月后,平均肌酐水平降至1.85mg/dL。2年随访后移植物存活率为72%。我们的经验表明,肾移植活检后选择性栓塞AVF是一种安全的手术,这种并发症的患者可以维持移植功能。
    The development of an arteriovenous fistula (AVF) after renal graft biopsy is a rare complication, it is associated in most cases with spontaneous resolution. However, interventional therapies are required in some cases, to prevent graft loss. Selective embolization has been described as an alternative treatment. In the present study, we describes our experience on AVF after biopsy in kidney transplant patients, which was managed with selective embolization. From 2005 to 2015, a total of 452 kidney transplant biopsies were performed, 12 had an AVF requiring embolization. In 92% of cases, this was successful. Beforehand, mean serum creatinine levels were 2.45 mg/dL, after the procedure, that increased to 3.05, however, 3 months later, mean creatinine levels dropped to 1.85 mg/dL. Graft survival after 2 follow-up years was 72%. Our experience demonstrates that selective embolization of the AVF after kidney transplant biopsy is a safe procedure, and that transplant function can be maintained in patients with this complication.
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