Scorbutic haemorrhaging

  • 文章类型: Journal Article
    目的:本研究旨在确定基底旁下表面孔隙和骨膜下新骨形成的病因。
    方法:总共199名年龄在妊娠36周至3.5岁之间的非成人个体,从英国总共12个考古遗址中,包括铁器时代(n=43),Roman(n=12),和后中世纪(n=145)遗址,还有一个保存完好的巴拉利斯。
    方法:将基底分为六段,具有多孔性(微观和宏观)和骨膜下新骨形成记录在下表面的珠光体和非珠光体个体。使用生物学方法开发的古病理学文献中的标准诊断了镰刀。
    结果:在所分析的6个区段中,有4个区段没有统计学上的显著差异。在非火山岩和火山岩个体中,年龄与微孔之间存在显着负相关。在珠光体和非珠光体个体之间观察到骨膜下新骨形成的显着差异。
    结论:在非成人骨骼遗骸(小于3.5年)的镰刀病宏观评估中,不应考虑基底下部的微孔性。
    结论:本研究强调了在过去人群中过度诊断为镰刀病的风险。
    结论:1岁以下个体骨骼的生理(正常)和病理(异常)骨骼变化难以区分。
    未来的研究应侧重于对3.5岁以上个体的分析。
    OBJECTIVE: This research aims to determine the aetiology of porosity and subperiosteal new bone formation on the inferior surface of the pars basilaris.
    METHODS: A total of 199 non-adult individuals aged 36 weeks gestation to 3.5 years, from a total of 12 archaeological sites throughout the UK, including Iron Age (n=43), Roman (n=12), and post-medieval (n=145) sites, with a preserved pars basilaris.
    METHODS: The pars basilaris was divided into six segments, with porosity (micro and macro) and subperiosteal new bone formation recorded on the inferior surface in scorbutic and non-scorbutic individuals. Scurvy was diagnosed using criteria from the palaeopathological literature that was developed using a biological approach.
    RESULTS: There was no statistically significant difference in microporosity between scorbutic and non-scorbutic individuals in four out of the six segments analysed. There was a significant negative correlation between age and microporosity in non-scorbutic and scorbutic individuals. A significant difference in subperiosteal new bone formation was observed between scorbutic and non-scorbutic individuals.
    CONCLUSIONS: Microporosity on the inferior pars basilaris should not be considered among the suite of lesions included in the macroscopic assessment of scurvy in non-adult skeletal remains (less than 3.5 years).
    CONCLUSIONS: This study highlights the risk of over diagnosing scurvy in past populations.
    CONCLUSIONS: It is difficult to distinguish between physiological (normal) and pathological (abnormal) bone changes in the skeleton of individuals less than one year of age.
    UNASSIGNED: Future research should focus on the analysis of individuals over 3.5 years of age.
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