Sclerochoroidal calcifications

脉络膜钙化
  • 文章类型: Case Reports
    我们提出了一个病例报告硬化脉络膜钙化(SCC),在一名70岁的患者中,这是一种罕见的疾病,涉及焦磷酸钙沉积在眼后极。我们介绍了临床表现及其在多模态图像中的外观,使用彩色眼底摄影,扫频源光学相干层析成像(SS-OCT),眼超声,和新颖的后向模式成像(RMI)技术。右眼(OD)视力为20/25,左眼(OS)视力为20/20。彩色眼底照相显示,两只眼睛的上颞区都有淡黄色的沉积物。SS-OCT显示巩膜源性肿块。眼部超声证实了这些肿块的钙化。RMI检测到具有明显表面高度的高反射图像。系统实验室检查结果未发现任何异常,导致双侧特发性SCC的诊断。
    We present a case report on sclerochoroidal calcification (SCC), a rare condition involving calcium pyrophosphate deposits in the posterior pole of the eye in a 70-year-old patient. We provide an account of the clinical presentation and its appearance in multimodal images, using color fundus photography, swept-source optical coherence tomography (SS-OCT), ocular ultrasound, and the novel retro-mode imaging (RMI) technique. Visual acuity was 20/25 in the right eye (OD) and 20/20 in the left eye (OS). Color fundus photography revealed yellowish deposits located in the upper temporal arcade of both eyes. SS-OCT demonstrated masses of scleral origin. Ocular ultrasounds confirmed the calcification of these masses. RMI detected hyper-reflective images with marked superficial elevation. Systemic laboratory results did not detect any abnormalities, leading to the diagnosis of bilateral idiopathic SCC.
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  • 文章类型: Case Reports
    BACKGROUND: Sclerochoroidal calcification (SCC) is a rare and benign condition found mostly in middle-aged and elderly Caucasian men, characterized by multiple yellow-white lesions seen most commonly in the temporal regions of the fundus. While they may be concerning for benign tumors, primary neoplasias or metastases, SCCs most commonly present as asymptomatic findings during routine ophthalmologic testing and have a very good prognosis as they rarely cause visual deficits.
    OBJECTIVE: To report and describe the findings in a case of bilateral idiopathic sclerochoroidal calcifications.
    METHODS: A retrospective case report.
    RESULTS: Repeated ophthalmological exams, including fundoscopic examination, ultrasonography, optical coherence tomography and fluorescein angiography, were all consistent bilateral idiopathic sclerochoroidal calcifications.
    CONCLUSIONS: While most cases of idiopathic sclerochoroidal calcifications represent a benign ophthalmological condition, there are known associations with other systemic conditions, such as hyperthyroidism, hyperparathyroidism, Bartter\'s syndrome and Gitelman\'s syndrome. It is for this reason that these patients warrant a full systemic work-up in addition to careful ophthalmological monitoring.
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  • 文章类型: Case Reports
    方法:一名69岁女性被转诊,在此过程中,眼底镜检查显示双眼的上颞叶中周边有白色黄色视网膜下病变。A和B扫描超声显示位于巩膜和脉络膜水平的高回声性病变。计算机断层扫描显示后外侧硬化脉络膜钙化。代谢研究显示严重的维生素D缺乏,没有其他显着发现。
    结论:硬化脉络膜钙化是一种罕见的发现,是由于巩膜和脉络膜水平的钙沉积而发生的。它们具有特征性的临床表现,在大多数情况下是特发性的,但可能与一些系统性疾病有关,如钙和磷代谢紊乱;这一事实值得进行彻底的代谢研究。我们报告了一例与严重维生素D缺乏相关的双侧硬化脉络膜钙化,没有其他明显的代谢发现。
    METHODS: A 69 year-old woman was referred for a routine visit, during which funduscopy revealed white-yellow subretinal lesions in the superotemporal mid-periphery of both eyes. A and B scan ultrasound showed hyperechogenic lesions located at scleral and choroidal level. Computed tomography revealed posterolateral sclerochoroidal calcifications. Metabolic studies showed a severe vitamin D deficiency with no other remarkable findings.
    CONCLUSIONS: Sclerochoroidal calcifications are an infrequent finding that occur as a result of calcium deposit at scleral and choroidal level. They have a characteristic clinical picture and are idiopathic in most cases, but may be associated with some systemic diseases, such as calcium and phosphorous metabolic disorders; this fact warrants a thorough metabolic study. We report a case of bilateral sclerochoroidal calcifications associated with severe vitamin D deficiency with no other significant metabolic findings.
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