根据欧盟委员会的要求,EFSA被要求就肉豆蔻种子中精油的安全性和有效性发表科学意见。(肉豆蔻油),当用作所有动物物种的饲料和饮用水中的感官添加剂时。该添加剂含有肉豆蔻素(高达12%),黄樟素(2.30%),elemicin(0.40%)和甲基丁香酚(0.33%)。对于长寿和生殖动物,动物饲料中使用的添加剂和产品或物质小组(FEEDAP)认为对蛋鸡和兔子在0.2mg/kg的完全饲料中使用添加剂的关注不高,母猪和奶牛0.3mg/kg,绵羊/山羊0.5mg/kg,马和猫,狗0.6mg/kg,观赏鱼2.5mg/kg。对于短命的动物来说,当添加剂在小牛的最大建议使用量为10mg/kg时,小组没有安全问题,用于育肥的牛,绵羊/山羊,用于肉类生产的马,鲑鱼和其他物种,火鸡的育肥剂量为3.3毫克/千克,2.8毫克/千克育肥鸡,仔猪5.0mg/kg,用于育肥的猪为6.0mg/kg,用于生产肉类的兔为4.4mg/kg。这些结论外推到其他生理相关物种。对于任何其他物种,该添加剂被认为是低关注0.2毫克/千克。预计在动物饲料中使用肉豆蔻油对消费者和环境没有影响。添加剂应被视为对皮肤和眼睛的刺激物以及皮肤和呼吸致敏剂。基于黄樟素的存在,肉豆蔻油被归类为致癌物(1B类)并相应处理。由于肉豆蔻油被认为是调味食品,它在饲料中的功能是相同的,认为没有进一步的疗效证明是必要的.
Following a request from the European Commission, EFSA was asked to deliver a scientific opinion on the safety and efficacy of an essential oil from the seeds of Myristica fragrans Houtt. (nutmeg oil), when used as a sensory additive in feed and water for drinking for all animal species. The additive contains myristicin (up to 12%),
safrole (2.30%), elemicin (0.40%) and methyleugenol (0.33%). For long-living and reproductive animals, the Panel on Additives and Products or Substances used in Animal Feed (FEEDAP) considered of low concern the use of the additive in complete feed at 0.2 mg/kg for laying hens and rabbits, 0.3 mg/kg for sows and dairy cows, 0.5 mg/kg for sheep/goats, horses and cats, 0.6 mg/kg for dogs and 2.5 mg/kg for ornamental fish. For short-living animals, the Panel had no safety concern when the additive is used at the maximum proposed use level of 10 mg/kg for veal calves, cattle for fattening, sheep/goats, horses for meat production, and salmon and for the other species, at 3.3 mg/kg for turkeys for fattening, 2.8 mg/kg chickens for fattening, 5.0 mg/kg for piglets, 6.0 mg/kg for pigs for fattening and 4.4 mg/kg for rabbits for meat production. These conclusions were extrapolated to other physiologically related species. For any other species, the additive was considered of low concern at 0.2 mg/kg. The use of nutmeg oil in animal feed was expected to be of no concern for consumers and the environment. The additive should be considered as irritant to skin and eyes and as a skin and respiratory sensitiser. Based on the presence of
safrole, nutmeg oil is classified as carcinogen (category 1B) and handled accordingly. Since nutmeg oil was recognised to flavour food and its function in feed would be the same, no further demonstration of efficacy was considered necessary.