UNASSIGNED:老年患者患有慢性疾病,并且容易进行多重用药和潜在的不适当处方(PIP)。这项研究旨在确定三级护理医院环境中老年患者中潜在的不适当药物(PIMs)和潜在的处方遗漏(PPOs),并估计多种药物的患病率。
UNASSIGNED:这项多中心回顾性观察性研究回顾了来自两家主要巴勒斯坦医院的患者数据。收集的数据包括患者的人口统计,合并症,以及住院和出院期间服用的药物。该研究包括2019年1月至2019年12月期间住院的247名年龄≥65岁的患者。STOPP/START标准第2版用于确定PIMs和PPOs的患病率。临床药师验证了数据,采用SPSS进行数据分析。描述性统计,单尾双变量相关性,和Pearson检验应用于感兴趣的变量,以检查它们与STOPP/START标准的关联。
UNASSIGNED:总共247名患者被纳入研究,女性占50.2%。因此,165名(66.8%)参与者被确定为PIP,包括30名PPOs患者,91与PIMs,44和两者。此外,住院和出院期间PIP的患病率分别为56.29%和64.39%,分别。在住院和出院期间,多药(5-9种药物)分别为44.5%和52.1%,分别,住院和出院期间,多药过量(十种药物或更多)分别为33.6%和16.4%,分别。此外,47.3%的患者的合并症指数≥5。
UNASSIGNED:这项研究发现,老年患者在入院和出院期间PIP的患病率很高。此外,在这项研究中,超过一半的老年患者患有PIP,且多重用药的患病率较高.因此,这项研究强调了适应循证工具的重要性,如STOPP/START标准,优化患者药物治疗,并指导处方者识别和解决PIM和PPO。
UNASSIGNED: Elderly patients suffer from chronic diseases and are prone to polypharmacy and potentially inappropriate prescribing (PIP). This study aimed to identify potentially inappropriate medications (PIMs) and potential prescribing omissions (PPOs) among elderly patients in a tertiary care hospital setting and to estimate the prevalence of polypharmacy.
UNASSIGNED: This multicenter retrospective observational study reviewed patient data from two major Palestinian hospitals. The collected data included patient demographics, comorbidities, and medications administered during hospitalization and discharge. The study included 247 patients aged ≥ 65 years hospitalized between January 2019 and December 2019. The STOPP/START criteria version 2 was used to identify the prevalence of PIMs and PPOs. Clinical pharmacists verified the data, and SPSS was used for data analysis. Descriptive statistics, one-tailed bivariate correlations, and Pearson\'s test were applied to the variables of interest to examine their association with the STOPP/START criteria.
UNASSIGNED: A total of 247 patients were included in the study, and 50.2% were females. As a result, 165 (66.8%) participants were identified with PIPs, including 30 patients with PPOs, 91 with PIMs, and 44 with both. Furthermore, the prevalence of PIP during hospitalization and discharge was 56.29% and 64.39%, respectively. Polypharmacy (5-9 medications) was 44.5% and 52.1% during hospitalization and discharge, respectively, and excessive polypharmacy (ten medications or more) was 33.6% and 16.4% during hospitalization and discharge, respectively. Moreover, 47.3% of the patients had a comorbidity index of ≥ 5.
UNASSIGNED: This study identified a high prevalence of PIPs among elderly patients during hospital admission and discharge. In addition, more than half of the geriatric patients in this study had PIP and a high prevalence of polypharmacy. Therefore, this study emphasizes the importance of adapting evidence-based tools, such as the STOPP/START criteria, to optimize patient medication therapy and guide prescribers in identifying and resolving PIMs and PPOs.