UNASSIGNED:年轻患者的急性心肌梗塞(AMI)是一个令人担忧的问题,因为它对健康和社会造成不利影响。然而,年轻患者AMI的危险因素和预后尚待确定。
UNASSIGNED:本研究旨在使用日本全国范围内的大规模注册数据,对接受初次经皮冠状动脉介入治疗(PCI)的年轻患者的AMI进行表征。日本经皮冠状动脉介入治疗(J-PCI)。
UNASSIGNED:这项回顾性队列研究评估了2014年1月至2018年12月期间接受原发性PCI的20至79岁AMI患者的J-PCI注册数据。风险因素概况数据,临床特征,术后并发症,并对住院结局进行了回顾.
UNASSIGNED:在213,297例接受原发性PCI的AMI患者中,有23,985例(11.2%)为年轻(20至49岁)。与老年组(50至79岁;n=189,312)相比,年轻的群体包括更多的男性,吸烟者,血脂异常患者,和患有单支血管疾病的患者,高血压和糖尿病患者数量较少。尽管临床情况良好,年龄较小与心肺骤停(CPA)的出现率较高相关.Further,在年轻患者中,合并CPA与住院死亡率密切相关(比值比:14.2;95%CI:9.2~21.9).
未经证实:年轻的AMI患者出现CPA的风险更高,这与住院死亡率密切相关。这项研究的结果强调了年轻人中初级AMI预防策略的重要性。
UNASSIGNED: Acute myocardial infarction (AMI) in young patients is a concerning issue because of its adverse health and social impacts. Nevertheless, risk factors and prognosis of AMI in young patients are yet to be characterized.
UNASSIGNED: This study aimed to characterize AMI in young patients who underwent primary percutaneous coronary intervention (PCI) using large-scale nationwide all-comer registry data in Japan, the Japanese Percutaneous Coronary Intervention (J-PCI).
UNASSIGNED: This retrospective cohort study evaluated the J-PCI registry data of patients with AMI aged 20 to 79 years who underwent primary PCI between January 2014 and December 2018. Data on risk factor profiles, clinical features, post-procedural complications, and in-hospital outcomes were reviewed.
UNASSIGNED: Among 213,297 patients with AMI who underwent primary PCI, 23,985 (11.2%) were young (ages 20 to 49 years). Compared with the older group (ages 50 to 79 years; n = 189,312), the younger group included a higher number of men, smokers, patients with dyslipidemia, and patients with single-vessel disease, and a lower number of patients with hypertension and diabetes. Despite favorable clinical profiles, younger age was associated with a higher rate of presentation with cardiopulmonary arrest (CPA). Further, concomitant CPA was strongly associated with in-hospital mortality in young patients (odds ratio: 14.2; 95% CI: 9.2 - 21.9).
UNASSIGNED: Younger patients with AMI presented a higher risk of CPA, which was strongly associated with in-hospital mortality. The results of this study highlight the importance of primary AMI prevention strategies in young individuals.