医疗器械的生产遵循严格的指导方针,其中生物和血液相容性,机械强度,抗撕裂性是重要的特征。链段聚氨酯(PU)是一类重要的聚合物,满足许多这些要求。因此,有理由研究具有增强性能的新型衍生物,如调节二氧化碳和氧气渗透性。在这项工作中,三段聚氨酯基膜,包含分散在软段(SS)块矩阵中的硬段(HS)块,通过PU预聚物(PUR)与三(羟甲基)氨基甲烷(TRIS)反应制备,刚果红(CR)和甲基-β-环糊精(MBCD),渲染PU/TRIS,PU/CR和PU/MBCD膜。纯(对照)PU膜在HS和SS之间表现出最高程度的相分离,其次是PU/TRIS和PU/MBCD膜。PU/CR膜表现出最高的混合程度。纯PU和PU/CR膜表现出最高和最低值的杨氏模量,切线模量和极限抗拉强度,分别,这表明CR的引入增加了分子的迁移率,从而降低刚度。PU/CR膜的CO2渗透率最高,347Barrer,和最低的纯PU膜,278Barrer,这表明HS和SS之间的混合程度更高导致更高的CO2渗透率。所有膜的O2渗透率相似,但是CA.比CO2渗透率低10倍。
The production of medical devices follows strict guidelines where bio- and hemocompatibility, mechanical strength, and tear resistance are important features. Segmented polyurethanes (PUs) are an important class of polymers that fulfill many of these requirements, thus justifying the investigation of novel derivatives with enhanced properties, such as modulated carbon dioxide and oxygen permeability. In this work, three segmented polyurethane-based membranes, containing blocks of hard segments (HSs) dispersed in a matrix of soft segment (SS) blocks, were prepared by reacting a PU prepolymer (PUR) with tris(hydroxymethyl)aminomethane (TRIS), Congo red (CR) and methyl-β-cyclodextrin (MBCD), rendering PU/TRIS, PU/CR and PU/MBCD membranes. The pure (control) PU membrane exhibited the highest degree of phase segregation between HSs and SSs followed by PU/TRIS and PU/MBCD membranes, and the PU/CR membrane displayed the highest degree of mixing. Pure PU and PU/CR membranes exhibited the highest and lowest values of Young\'s modulus, tangent moduli and ultimate tensile strength, respectively, suggesting that the introduction of CR increases molecular mobility, thus reducing stiffness. The CO2 permeability was highest for the PU/CR membrane, 347 Barrer, and lowest for the pure PU membrane, 278 Barrer, suggesting that a higher degree of mixing between HSs and SSs leads to higher CO2 permeation rates. The permeability of O2 was similar for all membranes, but ca. 10-fold lower than the CO2 permeability.