目的:我们描述了三例双侧乳头周围高反射卵形团状结构(PHOMS)的报告,他们各自的多模态成像,和视网膜神经纤维层(RNFL)随时间的分析。
方法:我们对三名患有PHOMS的儿科患者进行了详细的多模态成像。我们做了视力测试,然后进行生物显微镜和眼底检查,额外的光学相干断层扫描(OCT),眼底自发荧光(FAF),红外线(IR),荧光素血管造影(FA),扫描激光显微镜(SLO),和后向模式成像。此外,我们分析了连续几次就诊的RNFL厚度.
结果:多模态方法在所有眼中都表现出与PHOMS相似的特征,即使用SLO和复古模式工具进行特别划界和良好可视化的圆环状形状。在所有的眼睛,我们发现随着时间的推移,RNFL呈下降趋势。在右眼和左眼中,显示时的RNFL平均为152.33±25.42和130±18.33微米,分别。几周后,平均为142±30.34和125.67±14.84微米,分别。
结论:我们的报告显示,随着时间的推移,PHOMS患者的RNFL厚度有变薄的趋势。
OBJECTIVE: We describe a report of three cases of bilateral Peripapillary Hyperreflective Ovoid Mass-Like Structures (PHOMS), their respective multimodal imaging, and retinal nerve fiber layer (RNFL) analysis over time.
METHODS: We performed an elaborated multimodal imaging of three pediatric patients with PHOMS. We performed a visual acuity testing, followed by a biomicroscopic and fundus examination, an additional Optical Coherence Tomography (OCT), fundus autofluorescence (FAF), infra-red (IR), fluorescein angiography (FA), Scanning laser Ophtalmoscopy (SLO), and retro-mode imaging. Furthermore, we analyzed RNFL thickness over several consecutive visits.
RESULTS: The multimodal approach exhibited similar characteristics of PHOMS in all eyes, namely a torus-like shaped that was particularly demarcated and well visualized using SLO and retro-mode tool. In all the eyes, we found a downward trend of the RNFL over time. In both the right and left eye, RNFL at presentation averaged at 152.33 ± 25.42 and 130 ± 18.33 microns, respectively. Several weeks after, it averaged at 142 ± 30.34 and 125.67 ± 14.84 microns, respectively.
CONCLUSIONS: Our report shows a thinning trend of the RNFL thickness over time in patients with PHOMS.