Respiratory Aspiration

呼吸抽吸
  • 文章类型: Journal Article
    舌骨运动可能与卒中后吞咽困难(PSD)患者的误吸风险相关,但难以定量评估。这项研究旨在使用深度学习模型更有效,更准确地测量舌骨运动的距离,并确定该模型在PSD患者中的临床实用性。
    本研究纳入了发病6个月内的85名PSD患者。根据视频透视吞咽研究的结果,将患者分为抽吸组(n=35)和非抽吸组(n=50)。使用BiFPN-U-Net(T)架构构建的深度学习模型跟踪舌骨运动。水平测量舌骨运动的最大距离(Hmax),垂直(Vmax),和对角线(Dmax)。
    与非吸入组相比,抽吸组舌骨向各个方向的运动明显减少。Vmax曲线下面积最高,为0.715,灵敏度为0.680,特异性为0.743。预测误吸风险的Vmax临界值为1.61cm。尽管舌骨运动与其他临床特征之间没有发现显着关系,但当舌骨运动等于或大于临界值时,出院时口服进食的成功率明显更高。
    可以使用深度学习模型定量有效地测量PSD患者的舌骨运动。基于深度学习模型的舌骨运动分析似乎可用于预测误吸风险和恢复口服喂养的可能性。
    UNASSIGNED: Hyoid bone movement is potentially related to aspiration risk in post-stroke dysphagia (PSD) patients but is difficult to assess quantitatively. This study aimed to measure the distance of hyoid bone movement more efficiently and accurately using a deep learning model and determine the clinical usefulness of the model in PSD patients.
    UNASSIGNED: This study included 85 patients with PSD within 6 months from onset. Patients were grouped into an aspiration group (n = 35) and a non-aspiration group (n = 50) according to the results of a videofluoroscopic swallowing study. Hyoid bone movement was tracked using a deep learning model constructed with the BiFPN-U-Net(T) architecture. The maximum distance of hyoid bone movement was measured horizontally (H max), vertically (V max), and diagonally (D max).
    UNASSIGNED: Compared with the non-aspiration group, the aspiration group showed significant decreases in hyoid bone movement in all directions. The area under the curve of V max was highest at 0.715 with a sensitivity of 0.680 and specificity of 0.743. The V max cutoff value for predicting aspiration risk was 1.61 cm. The success of oral feeding at the time of discharge was significantly more frequent when hyoid movement was equal to or larger than the cutoff value although no significant relationship was found between hyoid movement and other clinical characteristics.
    UNASSIGNED: Hyoid bone movement of PSD patients can be measured quantitatively and efficiently using a deep learning model. Deep learning model-based analysis of hyoid bone movement seems to be useful for predicting aspiration risk and the possibility of resuming oral feeding.
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  • 文章类型: Case Reports
    背景技术异物吸入(FBA)是儿童期常见且严重的问题,需要早期识别和治疗。常见的并发症包括窒息,出血,感染,和气胸.在严重的异物阻塞病例中,窒息可能导致死亡。我们报告了一个有趣的案例,其中一个被遗忘的棉球被吸入肺部。案例报告一名5岁男孩因咳嗽6天和发烧4天被送往当地医院,入院时没有任何异物吸入的信息。实验室检查结果表明白细胞升高;因此,给予头孢丙齐作为抗感染治疗。然而,孩子的情况没有好转。计算机断层扫描显示左肺不张。考虑到孩子的情况很严重,他被转诊到我们医院进行诊断和治疗。转诊后,听诊显示左肺呼吸音减少。经过多学科的讨论,结合辅助检查结果,考虑了异物的可能性。他接受了硬支气管镜检查,证实左主支气管有黄白色异物,后来被证实为棉球。手术非常成功。最终,他的病情好转,出院了,没有额外的并发症。结论对于异物吸入史不明的儿童,如果反复肺部感染,建议进行支气管镜检查,低听诊呼吸音,或成像异常。手术方法的选择取决于异物的位置和类型以及外科医生的经验,这也非常重要。
    BACKGROUND Foreign body aspiration (FBA) is a common and serious problem in childhood that requires early recognition and treatment. Common complications include asphyxia, hemorrhage, infection, and pneumothorax. In severe cases of foreign body obstruction, death can result from asphyxia. We report an interesting case in which a forgotten cotton ball was inhaled into the lungs. CASE REPORT A 5-year-old boy presented to the local hospital with coughing for 6 days and fever for 4 days, without any information of foreign body aspiration upon admission. Laboratory findings indicated an elevated white blood cell; therefore, cefprozil was given as anti-infective treatment. However, the child\'s condition did not improve. A computed tomography scan showed left pulmonary atelectasis. Considering that the child\'s condition was serious, he was referred to our hospital for diagnosis and treatment. After referral, auscultation revealed decreased breath sounds over the left lung. After multidisciplinary discussion, combined with the results of auxiliary examination, the possibility of a foreign body was considered. He underwent rigid bronchoscopy, which confirmed a yellow-white foreign body in the left main bronchus that was later verified as a cotton ball. The operation was very successful. Eventually, his condition improved and he was discharged, without additional complications. CONCLUSIONS For children with unclear history of foreign body aspiration, bronchoscopy is recommended if there is recurrent pulmonary infection, low auscultation breath sounds, or abnormal imaging. The choice of surgical method depends on the location and type of foreign body and the experience of the surgeon, which is also very important.
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  • 文章类型: Journal Article
    异物吸入(FBA)是严重的可预防的儿科健康问题,也是儿童意外死亡的主要原因之一。虽然在成年人中不寻常,它通常被忽略为气道阻塞的原因,并造成严重后果。这项研究评估了Asir社区的意识和以前的FBA经验,沙特阿拉伯王国。使用经过验证的问卷,一项匿名在线调查是在870名18岁及以上的人中进行的。问卷用于收集有关受访者的个人和社会人口统计学特征的数据,以及他们在FBA的经历,以及参与者对FBA的知识和感知的严重性。如果分数在60%到100%之间,知识水平被认为是好的,如果分数低于60%,知识水平被认为是好的,如果分数在60%到100%之间,如果分数低于60%,那就不好了。大多数参与者(79.7%)是女性,48.1%的人年龄在18至30岁之间,72.9%拥有大学学位,30.6%是学生,26.9%在教育部门工作,43.6%的人报告月收入低于5000沙特里亚尔,19.8%的人认为自己是医疗保健从业者。尽管FBA的社区经验在研究参与者中相当高(70.6%),他们对FBA的认识水平不足。只有24.7%的受访者对FBA有良好的了解。年纪大了,作为一名保健医生,将FBA视为严重事件与良好知识显著相关(P<.001)。这项研究的结果表明,迫切需要提高社区对FBA的认识。为了降低FBA的发病率和死亡率,需要在社区和医疗机构开展健康教育工作,以教育人们早期诊断和管理疾病的严重性和重要性。
    Foreign body aspiration (FBA) is a serious preventable pediatric health problem and one of the main causes of accidental death in children. Although unusual in adults, it is often overlooked as a cause of airway obstruction with serious consequences. This study assessed awareness and previous FBA experiences in the Asir community, Kingdom of Saudi Arabia. Using validated questionnaire, an annonymous online survey was conducted among 870 people aged 18 years and above. The questionnaire was used to collect data about the personal and sociodemographic characteristics of the respondents, as well as their experiences with FBA, and participants\' knowledge and perceived seriousness of FBA. The level of knowledge was deemed good if the score ranged between 60% and 100%, and bad if the score fell below 60%The level of knowledge was deemed good if the score ranged between 60% and 100%, and bad if the score fell below 60%. The majority of the participants (79.7%) were females, 48.1% were aged 18 to 30 years, 72.9% had university degree, 30.6% were students, 26.9% worked in the educational sector, 43.6% reported monthly income of <5000 Saudi Riyals and 19.8% of them identified themselves as healthcarepractitioners. Although the community experience with FBA was considerably high (70.6%) among the study participants, their awareness levels about FBA were deficient. Only 24.7% of the respondents had good knowledge of FBA. Older age, being a health practitioner, and perceiving FBA as a serious incident were significantly associated with good knowledge (P < .001). The findings of this study indicate an urgent need to raise community awareness of FBA. To reduce FBA morbidity and mortality, health education efforts in community and healthcare settings are required to educate people about the seriousness and importance of early diagnosis and management of the condition.
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  • 文章类型: Journal Article
    摄入汽油会导致严重的肺部和胃肠道并发症。计算机断层扫描可以揭示特征性的发现。
    一名61岁的男子出现了胃肠道症状,随后在摄入约150毫升汽油后出现呼吸窘迫和精神状态改变。
    腹部计算机断层扫描显示肠内容物的典型三层外观,可能代表肠液,摄入的汽油,和气体。胸部计算机断层扫描显示双侧肺浸润与肺炎一致。
    在腹部计算机断层扫描中识别肠道内容物的特征性三层外观可能有助于诊断汽油摄入。
    UNASSIGNED: Ingestion of gasoline can cause severe pulmonary and gastrointestinal complications. Computed tomography may reveal characteristic findings.
    UNASSIGNED: A 61-year-old man had gastrointestinal symptoms, and subsequently developed respiratory distress and altered mental status after ingesting approximately 150 mL of gasoline.
    UNASSIGNED: Abdominal computed tomography revealed a characteristic three-layered appearance of intestinal contents, likely representing intestinal fluid, ingested gasoline, and gas. Chest computed tomography showed bilateral pulmonary infiltrates consistent with pneumonitis.
    UNASSIGNED: Recognition of the characteristic three-layered appearance of the intestinal contents on abdominal computed tomography might aid in the diagnosis of gasoline ingestion.
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  • 文章类型: Journal Article
    对于老年人来说,与肺吸入相关的风险很大,会严重影响他们的生活质量。因此,肺吸入风险的管理对于促进健康老龄化至关重要,老年人自我健康管理中经常被忽视的一个方面。加强老年人肺误吸风险的自我管理,我们组织了一个多学科小组,为老年人开发了一个智能的肺误吸风险分层管理系统。该系统根据老年人的个人环境,采用不同的问卷进行评估。此外,它利用老年人友好的格式,如图片,视频和动画,使老年人更容易理解肺误吸的发生和危害。这使他们能够主动采取预防措施来管理风险,从而实现肺误吸风险的自我管理。
    For the elderly, the risks associated with pulmonary aspiration are significant, and can severely impact their quality of life. Therefore, the management of pulmonary aspiration risk is crucial in promoting healthy aging, an aspect often overlooked in self-health management for the elderly. To enhance self-management of pulmonary aspiration risk among the elderly, we have organized a multidisciplinary team to develop an intelligent risk hierarchical management system on pulmonary aspiration for the elderly. This system tailors the assessment with different questionnaires based on the elderly individual\'s environment. Additionally, it utilizes elderly-friendly formats such as pictures, videos and animations, making it easier for seniors to comprehend the occurrence and hazards of pulmonary aspiration. This enables them to proactively take preventive measures to manage the risk, thus achieving self-management of pulmonary aspiration risk.
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  • 文章类型: Letter
    暂无摘要。
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  • 文章类型: Journal Article
    目的:气管支气管异物抽吸术是儿科常见的急症,也是儿童意外死亡的主要原因。即使进行身体检查,诊断有时仍然很困难。病史,和基本的X光片.这种挑战需要在全身麻醉下进行内窥镜检查,不管严重并发症的可能性。诸如呼气胸部X射线之类的策略减少不必要的内窥镜检查的益处仍然不确定。我们评估了呼气胸部X射线在检测气道异物方面的有效性,以潜在地减少对内窥镜的需要。
    方法:我们对疑似异物吸入的儿童进行了X线和内窥镜检查。
    结果:共有70名儿童被纳入研究。在这些中,19例(27.1%)标准胸部X线片显示病理结果。然而,当增加呼气胸部X光片时,病理X线检查增加至37例(52.9%)。在在场的36具异物中,只有2个没有被检测到。此外,3次胸部X光显示病理结果,而内窥镜检查显示正常。因此,整体灵敏度,特异性,正预测值,阴性预测值为94.4%,91.1%,91.9%,分别为93.9%。
    结论:呼气胸片的显着敏感性可以消除不必要的内窥镜检查,但应仅限于无法使用MDCT的中心。只有在听诊期间观察到持续的临床症状时,才应考虑内窥镜检查的性能。
    OBJECTIVE: Tracheobronchial foreign body aspiration is a common pediatric emergency and a leading cause of accidental deaths in children. The diagnosis remains sometimes difficult even with physical examination, medical history, and basic X-rays. This challenge necessitates the performance of endoscopy under general anesthesia, regardless of the potential for serious complications. The benefit of strategies like expiratory chest X-rays to reduce unnecessary endoscopies remains uncertain. We evaluated the effectiveness of expiratory chest X-rays in detecting airway foreign bodies to potentially reduce the need for endoscopies.
    METHODS: We retrospectively studied children with suspected foreign body aspiration who had X-ray and endoscopy.
    RESULTS: A total of 70 children were included in the study. Out of these, 19 cases (27.1 %) showed pathological findings on standard chest X-rays. However, when expiratory chest X-rays were added, the number of pathological radiographies increased to 37 cases (52.9 %). Out of the 36 foreign bodies that were present, only 2 were not detected. Furthermore, 3 chest X-rays displayed pathological results, while the endoscopies indicated normal findings. Consequently, the overall sensitivity, specificity, positive predictive value, and negative predictive value stood at 94.4 %, 91.1 %, 91.9 %, and 93.9 % respectively.
    CONCLUSIONS: The remarkable sensitivity of expiratory chest radiography can eliminate the need for unnecessary endoscopy, but it should be limited to centers lacking access to MDCT. The performance of endoscopy should only be considered when persistent clinical symptoms are observed during auscultation.
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  • 文章类型: Journal Article
    目的:评估耳鼻咽喉科联合内镜检查的有效性,肺科,和胃肠病学诊断和管理儿科患者的慢性误吸。
    方法:我们回顾了2013年1月至2023年7月期间接受协调内窥镜检查的慢性误吸患者的REDCap儿科空气消化数据库。患者人口统计学,合并症,手术发现,干预措施,并对结果进行了审查。
    结果:49例患者被诊断为误吸。他们的平均(SD)年龄为28(36)个月(范围1.2-163个月),超过一半的患者年龄小于24个月。在联合内窥镜检查中最常见的发现是喉裂(n=30),细菌培养阳性(n=18),病毒PCR阳性(n=17),和活动性反流诱导的食管炎/胃炎(n=9)。细菌培养阳性的患者与复发性肺炎病史相关(p=0.009)。内窥镜检查结果与患者人口统计学之间没有其他显着关联,合并症,或症状。25例(51%)在内窥镜检查时至少有2名不同的专家发现了多种异常,6例(12%)在所有3名专家中都有异常。
    结论:对于出现MBS误吸或提示慢性误吸的非特异性症状的儿科患者,应考虑采用协调内镜检查,以进行综合诊断和治疗。
    OBJECTIVE: To evaluate the effectiveness of coordinated endoscopy with otolaryngology, pulmonology, and gastroenterology in diagnosing and managing chronic aspiration in pediatric patients.
    METHODS: We reviewed our REDCap Pediatric Aerodigestive Database for patients with chronic aspiration who underwent coordinated endoscopy between January 2013 and July 2023. Patient demographics, comorbidities, operative findings, interventions, and outcomes were reviewed.
    RESULTS: Forty-nine patients were identified with a diagnosis of aspiration. Their mean (SD) age was 28 (36) months (range 1.2-163 months) with more than half of the patients younger than 24 months. The most common findings noted on combined endoscopies were laryngeal cleft (n = 30), positive bacterial culture (n = 18), positive viral PCR (n = 17), and active reflux-induced esophagitis/gastritis (n = 9). Patients with a positive bacterial culture were associated with a history of recurrent pneumonia (p = 0.009). There were no other significant associations between endoscopy findings and patient demographics, co-morbidities, or symptoms. Twenty-five (51 %) had multiple abnormalities identified by at least 2 different specialists at the time of endoscopy and 6 patients (12 %) had abnormalities across all three specialists.
    CONCLUSIONS: Coordinated endoscopy should be considered in pediatric patients presenting with aspiration on MBS or non-specific symptoms suggestive for chronic aspiration for comprehensive diagnosis and management.
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  • 文章类型: Journal Article
    在纤维内窥镜检查吞咽评估(FEES)中检测到的误吸与肺炎不一致,在FEES中检测到的其他吞咽安全性改变没有肺炎风险的证据。我们进行了一次动态,双向队列研究,涉及148名在三级大学医院有吞咽困难风险的受试者。我们的目的是确定由FEES期间检测到的吞咽安全性改变引起的肺炎风险。我们使用多元负二项回归模型来调整潜在的混杂因素。任何一致性气管吸入患者的肺炎发生率密度(IR)为26.6/100人年(RR7.25;95%CI:3.50-14.98;P<0.001)。在喉部穿透具有任何一致性的患者中,IR为19.7/100人年(RR7.85;95%CI:3.34-18.47;P<0.001),在咽部残留具有任何一致性的患者中为18.1/100人年(RR6.24;95%CI:2.58-15.09;P<0.001)。当调整吸入时,残留和渗透与肺炎的联系消失了,提示他们患肺炎的风险取决于是否存在误吸,只有误吸与肺炎独立相关.在单和多变量负二项回归模型中,肺炎风险的增加是显着的。我们发现,在FEES期间检测到吞咽困难和误吸的患者中,肺炎的风险独立增加。吞咽的口腔和咽部阶段的变化,没有愿望,并没有增加肺炎的风险。
    Aspiration detected in the fiberoptic endoscopy evaluation of swallowing (FEES) has been inconsistently associated with pneumonia, with no evidence of the risk of pneumonia from other alterations in swallowing safety detected in FEES. We conducted a dynamic, ambidirectional cohort study involving 148 subjects at risk of dysphagia in a tertiary university hospital. Our aim was to determine the risk of pneumonia attributed to alterations in swallowing safety detected during FEES. We used multivariate negative binomial regression models to adjust for potential confounders. The incidence density rate (IR) of pneumonia in patients with tracheal aspiration of any consistency was 26.6/100 people-years (RR 7.25; 95% CI: 3.50-14.98; P < 0.001). The IR was 19.7/100 people-years (RR 7.85; 95% CI: 3.34-18.47; P < 0.001) in those with laryngeal penetration of any consistency and 18.1/100 people-years (RR 6.24; 95% CI: 2.58-15.09; P < 0.001) in those with pharyngeal residue of any consistency. When adjusted for aspiration, the association of residue and penetration with pneumonia disappeared, suggesting that their risk of pneumonia is dependent on the presence of aspiration and that only aspiration is independently associated with pneumonia. This increased risk of pneumonia was significant in uni- and multivariate negative binomial regression models. We found an independently increased risk of pneumonia among patients with dysphagia and aspiration detected during FEES. Alterations in the oral and pharyngeal phases of swallowing, without aspiration, did not increase the risk of pneumonia.
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  • 文章类型: Journal Article
    早期诊断和治疗异物吸入(FBA)可显著改善患儿的整体预后。不同地区FBA的流行病学和临床特点存在显著差异。因此,我们在中国西部地区进行了一项真实世界的研究,有4000多名患者。这项研究的目的是提高对FBA类型的理解,它发生的具体月份,以及中国西部地区主要照顾者的分布特征。我们通过大数据中心收集了过去20年来在我们医院诊断为FBA的儿童的临床和流行病学数据。我们对同期在儿科健康诊所接受常规体检的健康儿童的数据进行匹配,以分析实际监护人数据的差异。来自五个省份的4227名患者被纳入本研究。99.4%(4202/4227)的患者通过硬质支气管镜取出异物,中位年龄为19个月,中位手术时间为16分钟。1月是1725名患者最常见的发病月,其次是二月,1027名患者最常见的异物类型是瓜子花生,种子和核桃,占47.2%,15.3%,和10.2%,分别。在FBA组,作为主要照顾者的祖父母比例为70.33%(2973/4227),显著高于健康组的63.05%(2665/4227)(P<0.01)。FBA最常见于1月和2月。超过60%的FBA发生在1至2岁之间,在由祖父母照顾的儿童中,FBA的发生率可能更高。刚性支气管镜可用于在16分钟的中位数内去除大多数抽吸的异物。
    The early diagnosis and treatment of foreign body aspiration (FBA) can significantly improve the overall prognosis of children. There are significant differences in the epidemiology and clinical characteristics of FBA in different regions. Therefore, we conducted a real-world study in the western region of China with over 4000 patients. The aim of this study was to improve the understanding of FBA in terms of its types, the specific months of its occurrence, and the distribution of primary caregiver characteristics in western China. We collected the clinical and epidemiological data of children who were diagnosed with FBA in our hospital over the past 20 years through a big data centre. We matched the data of healthy children who underwent routine physical examinations at the paediatric health clinic during the same period to analyse the differences in the data of actual guardians. A total of 4227 patients from five provinces were included in this study. Foreign bodies were removed by rigid bronchoscopy in 99.4% (4202/4227) of patients, with a median age of 19 months and a median surgical duration 16 min. January was the most common month of onset for 1725 patients, followed by February, with 1027 patients. The most common types of foreign objects were melon peanuts, seeds and walnuts, accounting for 47.2%, 15.3%, and 10.2%, respectively. In the FBA group, the proportion of grandparents who were primary caregivers was 70.33% (2973/4227), which was significantly greater than the 63.05% in the healthy group (2665/4227) (P < 0.01). FBA most commonly occurs in January and February. More than 60% of FBAs occur between the ages of 1 and 2 years, and the incidence of FBA may be greater in children who are cared for by grandparents. A rigid bronchoscope can be used to remove most aspirated foreign bodies in a median of 16 min.
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