目的:复合树脂修复体的耐久性低可归因于树脂牙本质粘结界面的降解。由于在粘合剂中存在亲水性组分,树脂牙本质结合界面的完整性容易受损,which,反过来,导致粘结强度降低。粘合剂的亲水性导致吸水,相分离,和树脂组分的浸出。因此,疏水性粘合剂可以有效地稳定树脂牙本质粘结界面的完整性和耐久性。
方法:我们通过用可光固化的漆酚单体部分替代双酚A二甲基丙烯酸缩水甘油酯(Bis-GMA),合成了一种新型的疏水性牙本质粘合剂。所生产的粘合剂的性能,包括转化程度,粘度,接触角,水吸附/溶解度,和机械强度,全面检查并与作为阳性对照的商业粘合剂AdperSingleBond2进行比较。使用微拉伸粘合强度测量来确定粘合性能,激光共聚焦显微镜,扫描电子显微镜观察,和纳米电容测试。最后,对新型粘合剂进行生物相容性测试,以确定其潜在的细胞毒性。
结果:在光固化漆酚含量为20%时,合成的胶粘剂具有很高的转化率和疏水性,低细胞毒性,良好的机械性能,和突出的粘合强度。
结论:将光固化漆酚引入牙本质粘合剂中可以显着增强其疏水性,机械,和粘合性能,证明了显著提高恢复寿命的潜力。
结论:光固化漆酚的整合使实验粘合剂具有几种增强的功能。这些显著的益处强调了该单体在临床实践中用于扩展应用的适用性。
OBJECTIVE: The low durability of composite resin restorations can be attributed to the degradation of the resin dentin bonding interface. Owing to the presence of hydrophilic components in the adhesive, the integrity of the resin dentin bonding interface is easily compromised, which, in turn, leads to a reduction in bond strength. The hydrophilic nature of the adhesive leads to water sorption, phase separation, and leaching of the resin component. Therefore, hydrophobic adhesives could effectively be used to stabilize the integrity and durability of the resin dentin bonding interface.
METHODS: We synthesized a novel hydrophobic dentin adhesive by partially replacing bisphenol A glycidyl dimethacrylate (Bis-GMA) with a light-curable urushiol monomer. The properties of the produced adhesive, including the degree of conversion, viscosity, contact angle, water sorption/solubility, and mechanical strength, were comprehensively examined and compared to those of the commercially adhesive Adper Single Bond2 as a positive control. The adhesive properties were determined using microtensile bond strength measurements, laser confocal microscopy, scanning electron microscopy observations, and nanoleakage tests. Finally, the novel adhesive was subjected to biocompatibility testing to determine its potential cytotoxicity.
RESULTS: At a light-curable urushiol content of 20 %, the synthesized adhesive exhibited high degrees of conversion and hydrophobicity, low cytotoxicity, good mechanical properties, and outstanding adhesive strength.
CONCLUSIONS: The introduction of the light-curable urushiol into dentin adhesives can significantly enhance their hydrophobic, mechanical, and bonding properties, demonstrating potential to significantly improve restoration longevity.
CONCLUSIONS: The integration of light-curable urushiol has endowed the experimental adhesives with several enhanced functionalities. These notable benefits underscore the suitability of this monomer for expanded applications in clinical practice.