背景:有两种已知类型的运动诱发的急性肾衰竭。一种是长期已知的肌红蛋白尿症引起的急性肾功能衰竭,由于严重的横纹肌溶解,另一种是最近公认的非肌红蛋白尿症引起的急性肾功能衰竭伴轻度横纹肌溶解。运动诱发的急性肾功能衰竭于1982年首次报道。非肌红蛋白尿症引起的急性肾功能衰竭与严重的下腰痛和斑片状肾血管收缩有关,它被称为运动后急性肾功能衰竭,因为它通常发生在运动后数小时。无氧运动(ALPE)后,也称为急性肾功能衰竭,伴有严重的腰痛和斑片状肾缺血。
目的:为医学文献做出重大贡献,因为它提出了一项研究,研究了一种不广为人知的运动诱发的急性肾功能衰竭,称为ALPE。
方法:我们进行了数据库搜索,选择了以英语或日语发表的论文。最后一次访问数据库搜索是在2022年9月1日。将这项研究的结果与其他病例系列中报告的结果进行了比较。
结果:该研究评估了肾性低尿酸血症是ALPE的关键危险因素。ALPE的发展是由于运动等风险因素的总和,低尿酸血症,非甾体抗炎药,血管升压药,和脱水。
结论:结论:低尿酸血症在ALPE的发展中起着关键作用,并且通常与无氧运动有关。ALPE的发展是运动等风险因素累积影响的结果,低尿酸血症,NSAIDs,血管升压药,和脱水。
BACKGROUND: There are two known types of exercise-induced acute renal failure. One is the long-known myoglobinuria-induced acute renal failure due to severe rhabdomyolysis, and the other is the recently recognized non-myoglobinuria-induced acute renal failure with mild rhabdomyolysis. Exercise-induced acute renal failure was first reported in 1982. Non-myoglobinuria-induced acute renal failure is associated with severe low back pain and patchy renal vasoconstriction, and it is termed post-exercise acute renal failure because it usually occurs hours after exercise. It is also called acute renal failure with severe loin pain and patchy renal ischemia after anaerobic exercise (ALPE).
OBJECTIVE: To makes a significant contribution to medical literature as it presents a study that investigated a not-widely-known type of exercise-induced acute renal failure known as ALPE.
METHODS: We performed a database search selecting papers published in the English or Japanese language. A database search was lastly accessed on September 1, 2022. The results of this study were compared with those reported in other case series.
RESULTS: The study evaluated renal hypouricemia as a key risk factor of ALPE. The development of ALPE is due to the sum of risk factors such as exercise, hypouricemia, nonsteroidal anti-inflammatory drugs, vasopressors, and dehydration.
CONCLUSIONS: In conclusion, hypouricemia plays a key role in the development of ALPE and is often associated with anaerobic exercise. The development of ALPE is a result of the cumulative effects of risk factors such as exercise, hypouricemia, NSAIDs, vasopressors, and dehydration.