背景:国家尼古丁减少政策可以降低吸烟对公众健康的影响。然而,减少香烟中的尼古丁可能会导致其他烟草产品的使用发生变化,如尼古丁电子烟装置,尤其是年轻人。产品使用结果可能取决于可用的尼古丁电子烟装置的特性。我们的目的是确定香烟尼古丁含量的影响,汽化装置尼古丁浓度,和选择吸烟的电子烟装置口味,vape,或弃权。
方法:早期年轻成年人(18-20岁,N=80),一生中至少两次报告每天吸烟和吸尼古丁的人参加了一项实验室研究。参与者接受了非常低的尼古丁含量(VLNC;0.4mg尼古丁/g烟草)或正常尼古丁含量(NNC;15.8mg/g)香烟。首先,参与者在分配的香烟或弃权之间进行选择.随后,参与者选择了两次香烟抽吸,2个vape泡芙,或弃权。Vaping装置尼古丁浓度(3mgvs.18mg/ml)和风味(烟草与非烟草)在受试者内部操纵。
结果:当只有香烟时,VLNC组和NNC组在香烟选择上没有差异.当尼古丁汽化装置同时可用时,与NNC组相比,VLNC组的吸烟选择较少。非烟草香料和较低的电子烟装置尼古丁浓度与较少的吸烟选择相关。
结论:尼古丁汽化装置的可用性减少了吸烟VLNC香烟的选择,低尼古丁和非烟草口味的电子烟装置导致吸烟的选择最少。监管机构应考虑替代烟草产品的可用性和特性可以减轻产品标准的影响。
结论:美国食品和药物管理局可能会制定降低尼古丁的产品标准,这将影响所有市售卷烟。受这项政策影响的一个重要人群是早期吸烟的年轻人。我们的目的是确定香烟尼古丁含量的影响,汽化装置尼古丁浓度,和选择吸烟的电子烟装置口味,vape,或弃权。降低香烟中的尼古丁含量,随着非烟草香料和较低的尼古丁浓度在电子烟装置,与最少的吸烟选择有关。监管机构应考虑替代烟草产品的可用性和特性可以减轻产品标准的影响。
BACKGROUND: A national nicotine reduction policy could reduce the public health toll of smoking. However, reducing nicotine in cigarettes may lead to changes in the use of other tobacco products such as nicotine vaping devices, particularly among young people. Product use outcomes may depend on characteristics of available nicotine vaping devices. We aimed to determine the impact of cigarette nicotine content, vaping device nicotine concentration, and vaping device flavors on choices to smoke, vape, or abstain.
METHODS: Early young adults (ages 18-20 inclusive, N=80) who reported smoking daily and vaping nicotine at least twice in their lifetime participated in a laboratory study. Participants received either Very Low Nicotine Content (VLNC; 0.4 mg nicotine/g of tobacco) or Normal Nicotine Content (NNC; 15.8 mg/g) cigarettes. First, participants chose between their assigned cigarette or abstaining. Subsequently, participants chose between 2 cigarette puffs, 2 vape puffs, or abstaining. Vaping device nicotine concentration (3mg vs. 18mg/ml) and flavor (tobacco vs. non-tobacco) were manipulated within-subjects.
RESULTS: When only cigarettes were available, there were no differences between the VLNC and NNC groups on cigarette choices. When the nicotine vaping device was concurrently available, the VLNC group made fewer choices to smoke than the NNC group. Non-tobacco flavors and lower vaping device nicotine concentration were associated with fewer choices to smoke.
CONCLUSIONS: Nicotine vaping device availability reduced choices to smoke VLNC cigarettes, and vaping devices with lower nicotine and non-tobacco flavors led to the fewest choices to smoke. Regulators should consider that the availability and characteristics of alternative tobacco products can moderate the product standard\'s impact.
CONCLUSIONS: The U.S. Food and Drug Administration may enact a reduced nicotine product standard that would affect all commercially-available cigarettes. One important population affected by this policy would be early young adults who smoke. We aimed to determine the impact of cigarette nicotine content, vaping device nicotine concentration, and vaping device flavors on choices to smoke, vape, or abstain. Lower nicotine in cigarettes, along with non-tobacco flavors and lower nicotine concentration in the vaping device, were associated with the fewest choices to smoke. Regulators should consider that the availability and characteristics of alternative tobacco products can moderate the product standard\'s impact.