Recurrent Giant cell tumor

复发性巨细胞瘤
  • 文章类型: Case Reports
    UNASSIGNED: The aim of the study was a case report of a right-sided recurrent giant cell tumor of the distal end of the femur.
    UNASSIGNED: A case of a 25-year-old male patient with a history of recurrent giant cell tumor of the right distal femur who presented with chief complaints of pain over right distal femur and stiffness in the right knee for 2 years with restricted knee movement and is unable to walk. He was diagnosed with recurrent giant cell tumor of the right of the distal femur and was treated with wide excision with mega prosthesis reconstruction.
    UNASSIGNED: Wide excision with mega prosthesis reconstruction showed a good functional range of motion with early rehabilitation, stability, and mobility of joints.
    UNASSIGNED: We recommend wide excision and reconstruction with mega prosthesis is an effective method compared to sandwich technique and nailing and can be successfully done in the case of recurrent giant cell tumor of the distal femur with a good outcome, functional range of motion, stability, and mobility of the joint with early rehabilitation though it is a technically demanding surgery. The knee joint could have been salvaged and the need for more extensive surgery could have been prevented, had the diagnosis of recurrent giant cell tumor was made earlier.
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  • 文章类型: Evaluation Study
    Giant cell tumors (GCTs) located in the distal radius are likely to recur, and the treatment of such recurrent tumors is very difficult. Here, we report our clinical experience in distal radius reconstruction with vascularized proximal fibular autografts after en-bloc excision of the entire distal radius in 17 patients with recurrent GCT (RGCT) of the distal radius.
    All 17 patients with RGCT in distal radius underwent plain radiography and/or magnetic resonance imaging (MRI) of the distal radius as the initial evaluation after hospitalization. Then the distal radius were replaced by vascularized proximal fibular autografts after en-bloc RGCT resection. We assessed all patients by using clinical examinations, plain radiography of the wrist and chest, and Mayo wrist scores in the follow-ups.
    After an average follow-up of 4.3 years (range: 1.5-10.0 years), no lung metastasis or local recurrence was detected in any of the 17 patients. In total, 14 patients had excellent or good functional wrist scores, 16 were pain free or had occasional pain, and 15 patients returned to work. The mean range of motion of the wrist was 101° (flexion-extension), and the mean grip strength was 77.2 % of the contralateral normal hand.
    En-bloc excision of the entire distal radius and distal radius reconstruction with a vascularized proximal fibular autograft can effectively achieve local tumor control and preserve wrist function in patients with RGCT of the distal radius.
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  • 文章类型: Case Reports
    背景:骨巨细胞瘤(GCT)是一种常见的良性原发性骨肿瘤,常见于股骨远端,胫骨近端和桡骨远端。据报道,肱骨远端很少有GCT病例。我们报告了一名25岁男性在左肱骨内侧髁和上髁复发性巨细胞瘤的不寻常表现。
    方法:患者3年前出现左肘溶解性病变。因为它是一个不常见的肿瘤部位,误诊为结核性骨髓炎,刮除不充分。患者在初次手术后一年出现肿瘤复发。我们对肿瘤进行了整块切除,明智地移除部分滑车。尽管计划重建,由于每次手术肘部稳定,因此发现没有必要。患者恢复了接近正常的肘部运动,没有不稳定。他的MayoElbow性能得分从30提高到85。随访2年无复发或转移。
    结论:虽然在肱骨远端很少见骨肿瘤,需要进行活检以确认该区域任何溶解性病变的诊断,以便进行适当的治疗。
    BACKGROUND: Giant cell tumour of bone (GCT) is a common benign primary bone tumour, seen commonly in the distal Femur, proximal Tibia and distal Radius. Very few cases of GCT are reported in distal humerus. We report an unusual presentation of recurrent Giant cell tumour in a 25 year old male in the medial condyle and epicondyle of left Humerus.
    METHODS: Patient presented elsewhere with lytic lesion of left elbow three years ago. As it is an uncommon site for tumors, it was misdiagnosed as tuberculous osteomyelitis and was inadequately curetted. Patient presented to us with recurrence of tumor one year after the primary surgery. We did en-bloc resection of the tumour, with judicious removal of partial trochlea. Though reconstruction was planned, it was found to be not necessary as the elbow was stable per-operatively. Patient regained near normal movements of the elbow with no instability. His Mayo Elbow Performance score improved from 30 to 85. There is no recurrence or metastasis of the tumor in the two-year follow-up.
    CONCLUSIONS: Though bone tumors are rare in distal Humerus, biopsy is needed to confirm the diagnosis of any lytic lesion in this region for proper management.
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