目的:比较中国儿童近视控制的效果,佩戴角膜塑形镜(ortho-k)或近视控制眼镜(MCS)一年。
方法:检索了212例患者的相关数据,基线近视为-5.00至-0.75D,散光≤1.50D,谁已经接受近视控制治疗的ortho-k(Euclid(OK1)或CRT(OK2))或MCS(Stellest(MCS1)或DIMS(MCS2))至少一年。根据球面等效屈光度(SER)(眼镜组)和眼轴长度(AL)(所有组)的变化,比较了四组的近视控制效果。检索到的数据,仅从右眼看,包括最佳矫正视力(BCVA),SER,对初次临床访视(基线)和1年访视时的AL进行了分析.
结果:尽管性别没有显着差异,圆柱功率,基线访视时观察到BCVA(P>0.05),基线年龄有显著差异,近视,四组间AL差异有统计学意义(P<0.05)。治疗1年后,四组的轴向伸长率(AE)差异无统计学意义(P=0.49)。AE,根据基线年龄和球面功率进行调整,OK1、OK2、MCS1、MCS2分别为0.19±0.15、0.18±0.14、0.19±0.19、0.20±0.18mm。只有年龄是与AE和SER增加显著相关的因素(P<0.05),所有组的AE与年龄之间呈负相关,而观察到的眼镜组的SER升高与基线年龄之间呈正相关。
结论:两种品牌的ortho-k镜片和MCS对于在中国现实环境中治疗的轻度至中度近视儿童具有相似的近视控制效果。一年的平均AE范围从0.18到0.20毫米,与以前使用ortho-k控制近视的报告相当。
OBJECTIVE: To compare the effectiveness of myopia control in Chinese children, who had been wearing either orthokeratology (ortho-k) lenses or myopia control spectacles (MCS) for one year.
METHODS: Relevant data were retrieved from 212 patients, with baseline myopia of -5.00 to -0.75 D, astigmatism ≤ 1.50 D, who had been undergoing myopia control treatment with either ortho-k (Euclid (OK1) or CRT (OK2)) or MCS (Stellest (MCS1) or DIMS (MCS2)) for at least one year. Myopia control effectiveness among the four groups was compared based on the change in spherical equivalent refraction (SER) (for the spectacle groups) and axial length (AL) (for all groups). Data retrieved, from the right eye only, included best corrected visual acuity (BCVA), SER, and AL at both the initial clinic visit (baseline) and the one-year visit was analysed.
RESULTS: Although no significant differences in gender, cylindrical power, or BCVA were observed at the baseline visit (P > 0.05), there were significant differences in baseline age, myopia, and AL among the four groups (P < 0.05). No significant difference in axial elongation (AE) was found among the four groups after one year of treatment (P = 0.49). AE, adjusted for baseline age and spherical power, were 0.19 ± 0.15, 0.18 ± 0.14, 0.19 ± 0.19, 0.20 ± 0.18 mm for OK1, OK2, MCS1, MCS2, respectively. Only age was a significantly factor associated with AE and SER increase (P < 0.05), with negative associations between AE and age in all groups and positive association between SER increase and baseline age in the spectacle groups observed.
CONCLUSIONS: Both brands of ortho-k lenses and MCS had similar myopia control effectiveness for mild to moderate myopic children treated in a real-world setting in China. Average AE in one year ranged from 0.18 to 0.20 mm, comparable to previous reports on myopia control using ortho-k.