背景:探讨勃起功能障碍(ED)和鼻出血(ES)与髂动脉粥样硬化程度的关系。
方法:在这项回顾性横断面研究中,我们对2016年1月至2020年12月在我们机构接受腹部CT扫描的所有连续男性患者进行了评估.通过邮件邀请患者(n=1272)参加研究,并返回两份评估ED(IIEF-5)和ES的问卷。在3个月期限内返回填写问卷的患者被纳入研究。通过未增强CT的钙评分评估髂总动脉(CIA)和髂内动脉(IIA)的动脉粥样硬化程度。根据报告的IIEF-5评分和相应的ED组进行结果分层。
结果:总计,437例患者(占接触者的34.4%)符合纳入标准。42例患者未达到预定的年龄要求(<75岁),并且由于在非增强CT上进行钙评分不可行,因此必须排除120例患者。最后,275例患者被纳入分析,并分为“非轻度”(n=146)和“中度-重度”(n=129)ED组。CIA+IIA中的钙评分(r=-0.28,p<0.001)和动脉粥样硬化病变数量(r=-0.32,p<0.001)与IIEF-5评分呈显著负相关,分别。当属于“无轻度”与“无轻度”时,患者在CIA+IIA钙评分(差异:167.4,p<0.001)和动脉粥样硬化病变数量(差异:5.00,p<0.001)方面存在显着差异。“中度-重度”ED组,分别。多元回归模型,在调整相关基线特征后,显示动脉粥样硬化CIA+IIA病变数是ED的独立预测因子(OR=1.05,p=0.036),其中CIA+IIA钙评分为非(OR=1.00031,p=0.20)。ES发作与IIEF-5评分无相关性(r=-0.069,p=0.25),CIA+IIA钙评分(r=-0.10,p=0.87)或动脉粥样硬化CIA+IIA病变数量(r=-0.032,p=0.60),分别。
结论:非增强腹部CT扫描显示髂动脉粥样硬化病变的数量与ED的严重程度相关。这可用于识别亚临床心血管疾病并量化未来心血管危险的风险。
背景:BASEC-Nr.2020-01637。
BACKGROUND: To investigate the association between erectile dysfunction (ED) as well as epistaxis (ES) in relation to the extent of iliac atherosclerosis.
METHODS: In this retrospective cross-sectional study, all consecutive male patients treated at our institution from 01/2016 to 12/2020 undergoing abdominal CT scan were evaluated. Patients (n = 1272) were invited by mail to participate in the study in returning two questionnaires for the evaluation of ED (IIEF-5) and ES. Patients who returned filled-in questionnaires within a 3-month deadline were included in the study. The extent of atherosclerosis in the common iliac artery (CIA) and the internal iliac artery (IIA) was assessed by calcium scoring on unenhanced CT. Stratification of results was performed according to reported IIEF-5 scores and consequential ED groups.
RESULTS: In total, 437 patients (34.4% of contacted) met the inclusion criteria. Forty-two patients did not fulfill predefined age requirements (< 75 years) and 120 patients had to be excluded as calcium scoring on nonenhanced CT was not feasible. Finally, 275 patients were included in the analysis and stratified into groups of \"no-mild\" (n = 146) and \"moderate-severe\" (n = 129) ED. The calcium score (r=-0.28, p < 0.001) and the number of atherosclerotic lesions (r=-0.32, p < 0.001) in the CIA + IIA showed a significant negative correlation to the IIEF-5 score, respectively. Patients differed significantly in CIA + IIA calcium score (difference: 167.4, p < 0.001) and number of atherosclerotic lesions (difference: 5.00, p < 0.001) when belonging to the \"no-mild\" vs. \"moderate-severe\" ED group, respectively. A multivariable regression model, after adjusting for relevant baseline characteristics, showed that the number of atherosclerotic CIA + IIA lesions was an independent predictor of ED (OR = 1.05, p = 0.036), whereas CIA + IIA calcium score was not (OR = 1.00031, p = 0.20). No relevant correlation was found between ES episodes and IIEF-5 scores (r=-0.069, p = 0.25), CIA + IIA calcium score (r=-0.10, p = 0.87) or number of atherosclerotic CIA + IIA lesions (r=-0.032, p = 0.60), respectively.
CONCLUSIONS: The number of atherosclerotic lesions in the iliac arteries on nonenhanced abdominal CT scans is associated with the severity of ED. This may be used to identify subclinical cardiovascular disease and to quantify the risk for cardiovascular hazards in the future.
BACKGROUND: BASEC-Nr. 2020 - 01637.