■美国国立卫生研究院规定黑人的代表权相等,土著,和临床研究中的有色人种(BIPOC)个体,但目前尚不清楚此类纳入是否已在临床精神病或首发精神病(FEP)高危个体的多中心研究中实现.评估纳入率对于了解精神病的社会决定因素和特别影响BIPOC个体的精神病风险非常重要。
■作者对1993年至2022年之间发表的关于北美精神病和FEP临床高风险的多中心研究研究的文献进行了系统回顾,以确定小鼠的内含率。使用在线系统审查工具,作者检查了2,278项研究的资格。12项研究符合所有纳入标准。数据被提取,和人口特征,社会经济地位,研究设计,并分析了每项研究使用的招募策略。
■在临床精神病高风险研究中,大多数(62%)的参与者是白人。与国家数据相比,临床高危人群的人口统计学特征在大多数小鼠人群中具有代表性.黑人参与者(43%)在FEP研究中占最大的比例,与他们在美国人口中的代表人数相比,人数过多。与临床高风险研究相比,FEP研究更有可能从社区心理健康中心招募参与者。
■尽管这些结果表明BIPOC个体在精神病研究中具有很高的代表性,存在改善对民族代表的关注的机会。作者为可能在未来的精神病研究样本中增加血液多样性的实践提供了建议。
UNASSIGNED: The NIH has mandated equal representation of Black, Indigenous, and people of color (BIPOC) individuals in clinical research, but it is unclear whether such inclusion has been achieved in multisite research studies of individuals at clinical high risk for psychosis or with first-episode psychosis (FEP). An assessment of inclusion rates is important for understanding the social determinants of psychosis and psychosis risk that specifically affect BIPOC individuals.
UNASSIGNED: The authors conducted a systematic review of the literature published between 1993 and 2022 of multisite research studies of clinical high risk for psychosis and FEP in North America to determine ethnoracial inclusion rates. Using an online systematic review tool, the authors checked 2,278 studies for eligibility. Twelve studies met all inclusion criteria. Data were extracted, and demographic characteristics, socioeconomic status, study design, and recruitment strategies used by each study were analyzed.
UNASSIGNED: Most (62%) of the participants in studies of clinical high risk for psychosis were White. Compared with national data, the demographic characteristics of individuals with clinical high risk were representative across most ethnoracial groups. Black participants (43%) made up the largest ethnoracial group in FEP studies and were overrepresented compared with their representation in the U.S. population. FEP studies were more likely to recruit participants from community mental health centers than were the studies of clinical high risk.
UNASSIGNED: Although these results suggest high representation of BIPOC individuals in psychosis research, opportunities exist for an improved focus on ethnoracial representation. The authors offer recommendations for practices that may increase ethnoracial diversity in future psychosis study samples.