背景:关于重度哮喘患者体力活动的数据很少。从2016年5月至2017年6月,在参与研究的104家非学术医院之一的肺科医生就诊的1502名重度哮喘成年患者被纳入本前瞻性研究。横截面,多中心研究,只要他们同意。身体活动按4个等级分类:1(无活动),2(偶尔),3(常规),或4(频繁)。根据这些水平描述临床和治疗参数。
结果:分别,440、528、323和99名患者的体力活动水平为1、2、3和4。控制哮喘患者的百分比随着身体活动而增加。治疗依从性与身体活动没有差异。肥胖患者的百分比,FEV1<60%的患者,和焦虑症患者,抑郁综合征,胃食管反流病,动脉高血压,糖尿病,阻塞性睡眠呼吸暂停-低通气综合征,骨质疏松症随着体力活动而减少。只有5%的患者接受了呼吸康复治疗。
结论:在这项大型研究中,在重度哮喘患者中,体力活动与疾病控制相关,且合并症较少.应鼓励其实践,并更经常地提供呼吸康复服务。
BACKGROUND: Data on physical activity in severe asthma are scarce. From May 2016 to June 2017, 1502 adult patients with severe asthma visiting a pulmonologist practicing in one of the 104 non-academic hospitals participating in the study were included in this prospective, cross-sectional, multicenter study, provided they gave consent. Physical activity was classified according to 4 levels: 1 (no activity), 2 (occasional), 3 (regular), or 4 (frequent). Clinical and therapeutic parameters were described according to these levels.
RESULTS: Respectively, 440, 528, 323, and 99 patients had physical activity of level 1, 2, 3, and 4. The percentage of patients with controlled asthma increased with physical activity. Treatment adherence did not differ with physical activity. Percentages of obese patients, patients with FEV1 <60%, and patients with anxiety, depressive syndrome, gastro-esophageal reflux disease, arterial hypertension, diabetes, obstructive sleep apnoea-hypopnoea syndrome, and osteoporosis decreased with physical activity. Respiratory rehabilitation was offered to only 5% of patients.
CONCLUSIONS: In this large study, physical activity is associated with disease control in severe asthma and with less comorbidity. Its practice should be encouraged and respiratory rehabilitation offered more often.