■中药的质量取决于其次级代谢产物的含量,随着栖息地适应和生态因素的变化。本研究的重点是金银花(LJF),一种关键的传统草药,并旨在评估生态因素如何影响其质量。
■我们开发了一种结合高效液相色谱(HPLC)指纹技术和MaxEnt模型的新评估方法,以评估生态因素对LJF质量的影响。MaxEnt模型用于预测当前和未来情景的合适栖息地,同时采用高效液相色谱法分析关键化合物的含量。我们还使用ArcGIS进行空间分析,以创建高质量的分区地图。
■分析确定了21个常见色谱峰,金丝桃苷的含量有很大差异,芦丁,绿原酸,Cynaroside,和异绿原酸A跨越不同的栖息地。确定了影响LJF分布的关键环境变量,包括温度,降水,和海拔。目前适宜的栖息地主要包括长江以南地区。在未来的气候情景下,合适的地区预计会发生变化,甘肃南部有显著的扩张,西藏东南部,和辽宁南部。空间分布图显示,优质LJF主要分布在河北中南部,河南北部,山东中部,四川中部,广东南部,和台湾。
■研究表明,合适的生长区域可以促进植物中某些次生代谢产物的积累,随着这些代谢物的积累变化。结果强调了根据栽培实践优化质量的必要性。HPLC指纹图谱技术和MaxEnt模型的集成为草药资源的保护和种植提供了宝贵的见解,为评价生态因子对中药质量的影响提供了新的视角。
UNASSIGNED: The quality of traditional Chinese medicine is based on the content of their secondary metabolites, which vary with habitat adaptation and ecological factors. This study focuses on Lonicera japonica Flos (LJF), a key traditional herbal medicine, and aims to evaluate how ecological factors impact its quality.
UNASSIGNED: We developed a new evaluation method combining high-performance liquid chromatography (HPLC) fingerprinting technology and MaxEnt models to assess the effects of ecological factors on LJF quality. The MaxEnt model was used to predict suitable habitats for current and future scenarios, while HPLC was employed to analyze the contents of key compounds. We also used ArcGIS for spatial analysis to create a quality zoning map.
UNASSIGNED: The analysis identified 21 common chromatographic peaks, with significant variations in the contents of Hyperoside, Rutin, Chlorogenic acid, Cynaroside, and Isochlorogenic acid A across different habitats. Key environmental variables influencing LJF distribution were identified, including temperature, precipitation, and elevation. The current suitable habitats primarily include regions south of the Yangtze River. Under future climate scenarios, suitable areas are expected to shift, with notable expansions in southern Gansu, southeastern Tibet, and southern Liaoning. The spatial distribution maps revealed that high-quality LJF is predominantly found in central and southern Hebei, northern Henan, central Shandong, central Sichuan, southern Guangdong, and Taiwan.
UNASSIGNED: The study indicates that suitable growth areas can promote the accumulation of certain secondary metabolites in plants, as the accumulation of these metabolites varies. The results underscore the necessity of optimizing quality based on cultivation practices. The integration of HPLC fingerprinting technology and the MaxEnt model provides valuable insights for the conservation and cultivation of herbal resources, offering a new perspective on evaluating the impact of ecological factors on the quality of traditional Chinese medicines.