全球范围内侵袭性真菌感染的病例数量大幅增加,这与越来越多的免疫抑制患者和抗真菌耐药性的上升有关。一些以前被认为对人类无害的真菌已经成为新兴的病原体。其中一种是淡紫色纯毛,一种普遍存在于环境中的丝状真菌,尤其是在空气和土壤中。淡紫色P.lilacinum属于导致透明真菌病的更大的一组透明真菌,由无色菌丝的真菌引起的真菌感染。虽然这是一组异质真菌,它们的普遍性有相似之处,传输方式,受影响的患者,以及诊断和治疗方面的困难。在透明质真菌病中,皮肤是受影响最大的器官之一,这就是为什么皮肤科医生的参与对于初步评估至关重要,因为及时识别和早期诊断这种情况可以防止危及生命的感染和死亡。在这次审查中,我们在同一组中覆盖了由淡紫色假单胞菌和其他真菌引起的皮肤透明质真菌病,包括镰刀菌,青霉,Scedosporium,龙须菜,Cremonum,和木霉属。
There has been a substantial increase in the number of cases of invasive fungal infections worldwide, which is associated with a growing number of immunosuppressed patients and a rise in antifungal resistance. Some fungi that were previously considered harmless to humans have become emerging pathogens. One of them is Purpureocillium lilacinum, a ubiquitous filamentous fungus commonly found in the environment, especially in the air and soil. P. lilacinum belongs to a bigger group of hyaline fungi that cause hyalohyphomycosis, a fungal infection caused by fungi with colorless hyphae. Although this is a heterogeneous group of fungi, there are similarities regarding their ubiquity, ways of transmission, affected patients, and difficulties in diagnostics and treatment. In hyalohyphomycosis, the skin is one of the most affected organs, which is why the involvement of dermatologists is crucial for the initial assessment, since the timely recognition and early diagnosis of this condition can prevent life-threatening infections and death. In this review, we covered cutaneous hyalohyphomycosis caused by P. lilacinum and other fungi in the same group, including Fusarium, Penicilium, Scedosporium, Scopulariopsis, Acremonium, and Trichoderma genera.