■全球,药物使用障碍(SUD)治疗的门诊计划越来越突出.为了评估这一趋势的更广泛的临床意义,我们调查了门诊患者接受治疗所经历的功能变化。
■我们描述了挪威门诊治疗诊所93名SUD患者的临床特征。使用配对样本t检验,我们检查了感知功能的变化,精神痛苦,和其他临床相关的结果变量在治疗过程中的5个月的时间间隔。
■我们获得了67名(72%)纳入患者的随访数据,完成疗程的患者与未进行随访评估的患者之间的患者相关因素没有显着差异。从研究纳入(时间0)(平均19.8,标准差±8.8)到其结论(时间1)(24.3,±9.3;t(66)=4.5,(95%CI:2.5-6.5,p<0.001),感知功能显着增加。我们还发现了大多数其他测量变量的显著改进,包括精神痛苦,自我报告的睡眠质量,躁动,和强迫性思维。与物质使用相关的变量显示适度,T1时无显著改善。
■在5个月的门诊治疗过程中,患者的主观体验功能明显改善。在T0具有最低功能水平的那些改善最大。结构化监测可能是个性化干预的有价值的临床工具,提高治疗效果,并支持临床决策过程。
UNASSIGNED: Globally, outpatient programs for substance use disorder (SUD) treatment have gained prominence. To assess the broader clinical implications of this trend we investigated shifts in functioning experienced by outpatients undergoing treatment.
UNASSIGNED: We describe the clinical characteristics of a cohort of 93 SUD patients in a Norwegian outpatient treatment clinic. Using paired-samples t-tests, we examined changes in perceived functioning, mental distress, and other clinically relevant outcome variables in a 5-month time interval during the treatment course.
UNASSIGNED: We obtained follow-up data for 67 (72%) of the included patients, with no significant difference in patient-related factors between those who completed the treatment course and those who were not assessed at follow-up. Perceived functioning increased significantly from study inclusion (Time 0) (mean 19.8, standard deviation ± 8.8) to its conclusion (Time 1) (24.3, ±9.3; t (66) = 4.5, (95% CI: 2.5-6.5, p < 0.001). We also identified significant improvement in most other measured variables, including mental distress, self-reported sleep quality, restlessness, and obsessive thinking. Substance use-related variables showed a modest, non-significant improvement at T1.
UNASSIGNED: During a 5-month course of outpatient treatment, patients\' subjective experience of functioning improved significantly. Those with the lowest functioning levels at T0 improved the most. Structured monitoring may be a valuable clinical tool for personalizing intervention, enhancing treatment outcomes, and supporting the clinical decision-making process.