背景:糖尿病患者经常面临心理挑战,尤其是抑郁症。这两种情况的共存可以显着影响个体的身心健康。本研究旨在通过实验研究探讨护士主导的运动训练对老年2型糖尿病合并抑郁患者的影响。通过为患者选择合适的锻炼计划,该研究旨在确定有效的策略来改善他们的身体健康和抑郁症状。此外,它旨在提供量身定制的运动建议,以提高这些患者的整体健康水平。
方法:根据患者病历中记录的干预措施选择观察组(n=53)和对照组(n=53)。将符合条件的患者确定为研究参与者。对照组接受标准药物治疗,而观察组在标准治疗的基础上进行强化运动训练,每天60-90分钟用于锻炼。在干预之前和之后,血糖指标,5-羟色胺(5-HT)和去甲肾上腺素(NE)的水平,抑郁自评量表(SDS),焦虑自评量表(SAS),匹兹堡睡眠质量指数(PSQI)和通用生活质量量表(GQOLI-74)评分进行评估,以评估运动训练干预的影响。
结果:干预后,空腹血糖(FBG)水平,餐后2小时血糖(PBG),与干预前相比,血红蛋白A1c(HbA1c)降低,运动组的水平低于对照组(p<0.05)。此外,干预后,患者的5-HT和NE水平升高,运动组的水平高于对照组(p<0.05)。此外,干预后,SDS和SAS评分下降,观察组改善更为显著(p<0.05)。此外,与对照组相比,运动组患者的睡眠质量和生活质量得到了改善(p<0.05)。
结论:护士指导的运动训练显示出改善糖尿病合并抑郁症患者血糖指数的显著能力。它不仅降低了抑郁和焦虑水平,而且增强了5-HT和NE的表达。此外,它有效地提高了患者的睡眠质量和生活质量。这些发现强调了护士主导的运动干预在临床推广和广泛应用的潜力。
BACKGROUND: Patients with diabetes often face psychological challenges, particularly depression. The coexistence of these two conditions can significantly impact both the mental and physical health of individuals. This study aims to investigate the effects of nurse-led exercise training on elderly patients diagnosed with type 2 diabetes mellitus and comorbid depression through experimental research. By selecting appropriate exercise programs for patients, the study seeks to identify effective strategies for improving both their physical health and depressive symptoms. Additionally, it aims to offer tailored exercise recommendations to enhance the overall well-being of these patients.
METHODS: The observation group (n = 53) and the control group (n = 53) were selected based on the interventions documented in the patients\' medical records, with eligible patients identified as research participants. The control group received standard medication, while the observation group engaged in intensive exercise training in addition to their standard treatment, dedicating 60-90 min per day to exercise. Prior to and following the intervention, blood glucose indices, levels of 5-hydroxytryptamine (5-HT) and norepinephrine (NE), self-rating depression scale (SDS), Self-Rating Anxiety Scale (SAS), Pittsburgh Sleep Quality Index (PSQI), and Generic Quality of Life Inventory (GQOLI-74) scores were assessed to evaluate the impact of the exercise training intervention.
RESULTS: Following the intervention, levels of fasting blood glucose (FBG), 2-h postprandial blood glucose (PBG), and Hemoglobin A1c (HbA1c) were reduced compared to pre-intervention levels, with the exercise group exhibiting lower levels than the control group (p < 0.05). Additionally, post-intervention, patients\' levels of 5-HT and NE increased, with the exercise group demonstrating higher levels than the control group (p < 0.05). Moreover, post-intervention, SDS and SAS scores decreased, with more significant improvements observed in the observation group (p < 0.05). Furthermore, the intervention improved sleep quality and quality of life among patients in the exercise group compared to those in the control group (p < 0.05).
CONCLUSIONS: Nurse-guided exercise training demonstrates a significant capacity to ameliorate glycemic indexes among patients with diabetes mellitus comorbid with depression. It not only diminishes depression and anxiety levels but also enhances the expression of 5-HT and NE. Furthermore, it effectively elevates patients\' sleep quality and quality of life. These findings underscore the potential of nurse-led exercise interventions for clinical promotion and widespread application.