Post-operative management

术后管理
  • 文章类型: Case Reports
    手部受伤,特别是涉及指骨和掌骨的骨折,在各种设置中都是常见的,包括工业环境。及时有效地管理这些伤害对于最大限度地减少长期残疾和促进重返工作岗位至关重要。此病例报告着重于克氏针(K线)固定后工业工人的中指骨骨折的康复。病人,一个24岁的男性,在操作电动冲压机时受伤。急诊手术是为了稳定骨折,由于手功能的持续困难,随后的物理治疗开始。康复方案旨在解决疼痛,提高运动范围,并通过被动的运动练习来增强握力,用动员技术运动,阻塞练习,和加强抓地力练习。结合了Mulligan的运动动员(MWM)概念,以促进快速缓解疼痛和恢复运动。康复四周后的随访评估显示疼痛水平显着改善,运动范围,力量,和整体生活质量。该案例强调了在工业环境中管理创伤性手外伤时,及时干预和全面康复策略的重要性,旨在优化治疗结果并促进成功重返工作岗位。
    Hand injuries, particularly fractures involving the phalanges and metacarpals, are common occurrences in various settings, including industrial environments. Prompt and effective management of these injuries is crucial to minimize long-term disability and facilitate return to work. This case report focuses on the rehabilitation of a middle phalangeal fracture in an industrial worker following Kirschner wire (K-wire) fixation. The patient, a 24-year-old male, sustained the injury while operating an electric stamping machine. Emergency surgery was performed to stabilize the fracture, and subsequent physiotherapy was initiated due to persistent difficulties in hand function. The rehabilitation protocol aimed to address pain, improve range of motion, and enhance grip strength through passive range of motion exercises, movement with mobilization techniques, blocking exercises, and grip strengthening exercises. Mulligan\'s mobilization with movement (MWM) concept was incorporated to facilitate rapid pain relief and movement restoration. Follow-up assessments after four weeks of rehabilitation revealed significant improvements in pain levels, range of motion, strength, and overall quality of life. The case underscores the importance of timely intervention and comprehensive rehabilitation strategies in managing traumatic hand injuries in industrial settings, aiming to optimize treatment outcomes and promote successful return to work.
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  • 文章类型: Journal Article
    整骨手法治疗(OMT)是整骨医师在各种医疗环境中使用的一种疗法。术后,OMT可用于优化身体的功能和恢复。这项荟萃分析检查了OMT在减少术后住院时间方面的功效。鉴于长期住院对患者和医疗资源的重大影响,安全缩短这一时期的研究策略至关重要。这项荟萃分析检查了五项精选研究,这些研究测量了接受OMT的术后患者与未接受OMT的术后患者的住院时间。在我们的统计分析中应用了随机效应模型,以解释由于外科手术的差异而引起的异质性。医院,和患者人群。个别地,三项研究报告了OMT患者住院时间的统计学显着减少,而两个没有。这个荟萃分析,包括五项研究和519名患者,发现OMT的平均差为-2.37天;然而,这一发现没有达到统计学意义(P=0.06).观察到的实质性异质性(异质性tau2=6.75,chi2=34.6,df=4,P<0.00001,I2=88%)表明五项研究之间的临床差异可能导致我们的结论。虽然OMT在术后护理中显示出希望,需要采用标准化方案和更同质的患者群体进行进一步研究,以评估其真正影响.
    Osteopathic manipulative treatment (OMT) is a therapy used by osteopathic physicians in various medical settings. Postoperatively, OMT can be utilized to optimize the body\'s function and recovery. This meta-analysis examines the efficacy of OMT in reducing the length of postoperative hospital stays. Given the significant implications of prolonged hospitalization for both patients and healthcare resources, research strategies to safely shorten this period are crucial. This meta-analysis examined five select studies that measured the length of hospital stay in postoperative patients who received OMT compared with postoperative patients who did not. A random effects model was applied in our statistical analysis to account for heterogeneity due to variations in surgical procedures, hospitals, and patient populations. Individually, three studies reported statistically significant reductions in hospital stay for OMT patients, while two did not. This meta-analysis, comprising five studies and 519 patients, found a mean difference of -2.37 days in favor of OMT; however, this finding did not reach a statistical significance (P = 0.06). The substantial heterogeneity observed (heterogeneity tau2 = 6.75, chi2 = 34.6, df = 4, P < 0.00001, I2 = 88%) suggests that clinical dissimilarities among the five studies may have resulted in our inconclusive findings. While OMT shows promise in postoperative care, further research with standardized protocols and more homogenous patient populations is needed to assess its true impact.
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  • 文章类型: Journal Article
    手术后康复中经常使用电刺激(ES)和通过受激辐射(LASER)治疗的光放大;但是,目前没有足够的研究来比较它们的有效性。本研究旨在通过比较ES和LASER疗法与运动结合,评估内侧髌骨脱位(MPL)手术矫正后术后康复的有效性。将其与仅由所有者实施的术后家庭锻炼组成的对照组进行比较。
    我们对接受MPL手术治疗的狗进行了前瞻性临床试验。将狗分为以下三组:对照组,没有参加任何术后康复计划;ES组,接受了包括ES治疗的术后康复治疗;激光组,接受了以激光疗法为特征的术后康复。
    在评估参数方面,各组之间没有显着差异,包括跛行得分,疼痛评分,大腿肌肉周长,和运动范围。尽管某些组的疼痛评分可能存在差异,这可能归因于患者的术前状况。这些结果与所有者问卷的犬简短疼痛清单评估一致,显示治疗组之间无显著差异。
    MPL矫正的术后康复可能会增强肢体使用率,联合功能,肌肉质量,和疼痛缓解。然而,术后疼痛的持续时间和程度可能会影响康复的必要性.此外,ES和激光疗法在MPL手术后提供类似的疼痛缓解效果;因此,这些方法之间的选择取决于设备的可用性和兽医的喜好。
    UNASSIGNED: Electrical stimulation (ES) and light amplification by stimulated emission of radiation (LASER) therapy are frequently used in post-operative rehabilitation; however, there is currently insufficient research comparing their effectiveness. This study aimed to assess the effectiveness of post-operative rehabilitation following medial patellar luxation (MPL) surgical correction by comparing ES and LASER therapy when combined with exercise. This was compared with a control group that consisted solely of post-operative home exercise implemented by the owner.
    UNASSIGNED: We conducted a prospective clinical trial on dogs that had undergone surgical treatment for MPL. The dogs were categorized into the following three groups: The control group, which did not participate in any post-operative rehabilitation program; the ES group, which received post-operative rehabilitation involving ES therapy; and the LASER group, which underwent post-operative rehabilitation featuring LASER therapy.
    UNASSIGNED: There were no significant differences among the groups regarding the evaluation parameters, including lameness score, pain score, thigh muscle circumference, and range of motion. Although there may have been a difference in pain score in some groups, it could be attributed to the pre-operative condition of patients. These results aligned with the owner questionnaires\' canine brief pain inventory assessments, showing no significant differences between treatment groups.
    UNASSIGNED: Post-operative rehabilitation for MPL correction may enhance limb usage, joint function, muscle mass, and pain relief. However, the duration and level of post-operative pain may influence the necessity for rehabilitation. In addition, ES and LASER therapy offer similar pain-relieving effects after MPL surgery; therefore, the choice between these methods depends on the availability of equipment and veterinarian preferences.
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  • 文章类型: Case Reports
    肩关节具有复杂的解剖学和生物力学。它是由肩胛骨的肱骨头(球)和颅骨窝(窝)的关节表面制成的球窝关节。当肩关节的部分受到严重影响和损坏而无法修复时,进行肩关节成形术。损坏的零件更换为人造零件。假体植入物通常由金属或塑料材料制成。植入物有各种尺寸和形状。有三种类型的手术关节成形术:全肩关节成形术,部分肩关节成形术,和反向关节成形术。肩关节成形术的适应症可能包括骨关节炎,骨折,肩袖损伤,骨坏死,和类风湿性关节炎。本病例研究旨在提供一例左肩前下脱位伴肱骨头粉碎性骨折的病例,该病例经X线片和CT扫描等研究证实,并通过左肩关节置换术进行手术管理。在这个案例研究中,一名58岁的男性在手术后无法抬起手臂并独立进行肩关节动作,从而降低功能状态和生活质量。左肩关节置换术后修复后由于康复不充分,未能达到射程并获得肌肉的力量。病人有一个综合的行动计划,其中包括药物干预和物理治疗康复。物理治疗方案包括使用电肌肉刺激等目标,肌肉的激活练习,加强协议,伸展,和咨询。在理疗结束时,患者在重建范围和增强肌肉力量方面表现出重大进展,这导致了积极的自我提升以及改善的功能独立性商,从而提高生活质量。
    The shoulder joint has a complex anatomy and biomechanics. It is a ball and socket joint made by the articulation surface of the humeral head (ball) and glenoidal fossa (socket) of the scapula. Shoulder arthroplasty is done when parts of the shoulder joint are severely affected and damaged beyond repair. The damaged parts are replaced with artificial parts. Prosthetic implants are typically made of metal or plastic material. Implants come in various sizes and shapes. There are three types of surgical arthroplasty: total shoulder arthroplasty, partial shoulder arthroplasty, and reverse arthroplasty. Indications of shoulder arthroplasty may include osteoarthritis, fractures, rotator cuff injuries, osteonecrosis, and rheumatoid arthritis. This case study aims to provide a case of anteroinferior dislocation of the left shoulder with humeral head comminuted fracture confirmed by an investigation like radiograph and CT scan operatively managed by left shoulder hemiarthroplasty. In this case study, a 58-year-old male cannot lift his arm and perform actions of the shoulder joint independently after the operative procedure, thus reducing the functional status and quality of life. After the left shoulder hemiarthroplasty repair post due to inadequate rehabilitation, there was a failure in achieving the ranges and gaining back the strength of the muscles. The patient has a combined plan of action, which consists of pharmacological interventions along with physiotherapy rehabilitation. The physiotherapy protocol consists of goals like using electrical muscle stimulation, activation exercises of muscles, strengthening protocol, stretches, and counselling. By the end of the physiotherapy treatment, the patient showed significant progress in re-establishing the ranges and enhanced muscle strength, which resulted in a positive self-boost along with improved functional independence quotient, thereby increasing quality of life.
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  • 文章类型: Journal Article
    背景技术最大限度地减少不必要的支出对于应对对卫生部门的高要求至关重要。一组全血细胞计数,电解质,在国家卫生服务(NHS)中,肌酐和尿素测试的费用为12英镑。确定在初次膝关节和髋关节置换术后需要进行术后血液检查的选定患者将避免不必要的检查,并有助于减少支出。我们研究的目的是提出要求安全且不会错过患者的术后血液检查的标准。材料和方法我们前瞻性评估了126例接受选择性原发性THR或TKR的患者(全膝关节置换(TKR)组72例,全髋关节置换(THR)组54例)。患者平均年龄为71岁。记录每位患者住院期间的患者人口统计学和住院事件。术后90天也监测医院再入院。使用SPSSStatistics软件(IBMCorp.,Armonk,NY)采用配对t检验/Wilcox和混合测量方差分析。二元逻辑回归用于确定需要术后血液检查的患者的预测因素。结果对我们的数据进行分析,确定以下是需要进行术后全血计数检查的危险因素,包括术前Hb≤110g/L,心脏病,术后贫血的临床特征和术中失血量>500mL。确定需要术后电解质和尿素测试的其他风险因素是术前电解质紊乱以及电解质/肾脏紊乱的临床体征或症状,例如无尿。出院90天内无患者再次入院。结论总体来说,应用我们设计的标准,在126例患者的队列中可以节省74项血液检查.这提供了14.0的比值比(95%置信区间:1.77-110,p=0.012)的患者的异常结果,与那些没有经过测试的人相比。
    Background Minimising unnecessary expenditure is essential to cope with high demands on the health sector. A set of full blood count, electrolyte, creatinine and urea tests cost £12 in the National Health Service (NHS). Identifying selected patients requiring postoperative blood tests following primary knee and hip arthroplasty will avoid unnecessary tests and help to reduce expenditure.  The aim of our study is to propose criteria for requesting postoperative blood tests that are safe and do not miss patients. Materials and methods We prospectively evaluated 126 patients (72 in the total knee replacement (TKR) group and 54 in the total hip replacement (THR) group) who underwent either an elective primary THR or a TKR. The mean patient age was 71 years. Patient demographics as well as in-patient events throughout each patient\'s hospital stay were recorded. Hospital readmissions were also monitored for up to 90 days postoperatively.  Statistical analysis was performed using SPSS Statistics software (IBM Corp., Armonk, NY) with paired t-tests / Wilcox and mixed measures analysis of variance. Binary logistic regression was used to identify predictors of patients requiring a postoperative blood test. Results Analysis of our data identified the following as risk factors for requiring postoperative full blood count tests, including pre-operative Hb of ≤ 110 g/L, cardiac disease, clinical features of anaemia postoperatively and intraoperative blood loss of > 500 mL. The additional risk factors identified for requiring postoperative electrolyte and urea tests are deranged pre-operative electrolytes and clinical signs or symptoms of electrolyte/renal disturbance such as anuria. No patient was readmitted within 90 days of discharge. Conclusion Overall, applying the criteria we have devised would have saved 74 blood tests in the cohort of 126 patients. This provides an odds ratio of 14.0 (95% confidence interval: 1.77-110, p=0.012) of an abnormal result in the patients that would have been tested, compared to those that would not have been tested.
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  • 文章类型: Journal Article
    目的:距下关节是一种治疗柔性扁平足的微创技术。有关程序的一些问题仍在辩论中,如术后管理。这项研究的目的是对相关文献进行回顾,以确定当前的术后方案并描述它们之间可能的差异。
    方法:我们在PubMed数据库中搜索了所有与儿童距下关节相关的论文,并指定了术后方案。在根据排除标准审查所有研究后,选取50篇文章进行分析。
    结果:在文献综述的基础上,不同的术后方案出现在治疗患者的治疗中,特别是关于住院时间,固定的类型和持续时间,承重管理,通过康复计划,运动恢复和植入物移除。
    结论:最重要的发现是儿童距下关节病后的术后管理存在多种变化,从而证实在这一领域仍然没有明确的共识。
    OBJECTIVE: Subtalar arthroereisis is a minimally-invasive technique for the treatment of flexible flatfoot. Some issues regarding the procedure are still debated, such as post-operative management. The aim of this study is to offer a review of the pertaining literature to identify current post-operative protocols and describe possible differences among them.
    METHODS: We searched the PubMed database for all papers related to subtalar arthroereisis in children specifying the post-operative protocols. After reviewing all studies according to excluding criteria, 50 articles were selected for analysis.
    RESULTS: Based on the literature review, different post-operative protocols emerged in the treatment of patients undergoing subtalar arthroereisis, in particular regarding length of hospital stay, type and duration of immobilization, weight-bearing management, adopted rehabilitation scheme, sport resumption and implant removal.
    CONCLUSIONS: The most important finding was the existence of a wide variety in post-operative management after subtalar arthroereisis in children, thus confirming that no clear consensus still exists in this field.
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  • 文章类型: Journal Article
    UNASSIGNED:描述一种新颖的方法,该方法将封闭系统的抽吸引流器转换为高效的封闭系统的重力依赖性引流器,并在离体模型中证明其功效。
    UNASSIGNED:我们回顾了5本最畅销的泌尿外科和外科文本/参考书,以获取有关引流系统的信息。设计了一种离体模型,该模型具有与Jackson-Pratt灯泡排水管相连的流体储存器。我们测量了在抽吸和非抽吸时从储存器排出到灯泡中的流体的体积。这是重复使用一个新的修改的灯泡,其中灯泡的流出塞被单向阀取代,单向阀的方向允许从灯泡释放压力。
    UNASSIGNED:灯泡吸住,无论排水沟相对于水库的高度如何,都保持排水。随着灯泡的关闭,只有当排水口在储液罐下方时,才会发生封闭的被动重力依赖性排水;排水以最小的体积停止。增加了单向阀,并将灯泡保持在储液罐的液位以下,排水继续完成。
    UNASSIGNED:在领先的泌尿外科和普外科教科书/参考书中没有描述外科引流的工作原理。在不允许从灯泡腔中释放置换空气的情况下,不能使用封闭系统的抽吸排水管来实现被动的依赖重力的引流。我们描述的新型改进型排水器可提供可逆的封闭系统吸力和被动排水。
    UNASSIGNED: To describe a novel method to convert a closed-system suction drain to a highly efficient closed-system gravity-dependent drain and demonstrate its efficacy in an ex-vivo model.
    UNASSIGNED: We reviewed the 5 top-selling urology and surgery text/reference books for information on drainage systems. An ex-vivo model was designed with a reservoir of fluid connected to a Jackson-Pratt bulb drain. We measured the volume of fluid drained from the reservoir into the bulb while on-suction and off-suction. This was repeated using a novel modified bulb, where the bulb\'s outflow stopper was replaced with a one-way valve oriented to allow release of pressure from the bulb.
    UNASSIGNED: With the bulb on-suction, drainage was maintained regardless of the height of the drain relative to the reservoir. With the bulb off-suction, closed passive gravity-dependent drainage occurred only when the drain was below the fluid reservoir; drainage ceased at minimal volumes. With addition of a one-way valve and maintenance of the bulb below the level of the reservoir, drainage proceeded to completion.
    UNASSIGNED: How surgical drains work is not described in the leading urology and general surgery textbooks/reference books. Closed-system suction drains cannot be used to achieve passive gravity-dependent drainage without allowing release of displaced air from the bulb-lumen. The novel modified drain we describe affords reversible closed-system suction and passive drainage.
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  • 文章类型: Case Reports
    Triplex(TerumoCorp,东京,日本)是一种相对较新的血管假体,具有不可生物降解的涂层材料。术后我们在Triplex移植物中经历了两例移植物伸长。在其中一个案例中,移植物伸长导致左锁骨下动脉闭塞。在另一种情况下,移植物伸长导致升主动脉假性动脉瘤。Triplex移植物的一个独特特征是它们可以减少术后炎症反应;然而,它们也可能引起与周围组织的有限粘连形成,有助于假体伸长,由于缺乏假体的稳定性和固定。需要根据植入假体的特征进行仔细观察。
    Triplex (Terumo Corp, Tokyo, Japan) is a relatively new vascular protheses with a non-biodegradable coating material. We experienced two cases of graft elongation in Triplex grafts post-operatively. In one of the cases, the graft elongation led to occlusion of the left subclavian artery. In the other case, the graft elongation resulted in a pseudoaneurysm of the ascending aorta. A unique feature of Triplex grafts is that they may reduce post-operative inflammation reaction; however, they could also invite a limited adhesion formation with the surrounding tissue, which contribute to prostheses elongation, due to a lack of prostheses stability and fixation. A careful observation based on the feature of implanted protheses is required.
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  • 文章类型: Journal Article
    目的比较术后第0天(POD0)和术后第1天(POD1)的单纯性白内障手术的术后结局和治疗方法。方法对2018年12月至2020年3月手术后0-14天内随访的患者进行回顾性队列研究(当前程序术语代码66984)。那些围手术期并发症的人,那些结合了青光眼滤过手术以及其他微创青光眼手术(MIGS)程序的人,那些在手术后14天内没有完成前两次随访的患者被排除在外.视敏度(VA),眼内压(IOP),术后干预,收集术后第一次和第二次访视的并发症。结果在665名参与者中,平均(标准差)年龄为68(11)岁,60%为女性(n=304),最小分辨角(logMAR)VA的术前对数平均值(SD)为0.715(0.625).大约三分之一(32%)的患者在POD0上看到。与POD1相比,较高百分比的青光眼患者出现POD0(23%vs14%;p=0.008)。POD0的平均VA为0.840(0.653),显著低于POD1的平均VA值0.539(0.599)(p<0.0001)。第二次术后随访时,VA没有显着差异。术后第一次就诊时POD0组和POD1组之间的IOP没有显着差异。术后滴注方案最常见的变化与眼压和炎症控制有关。干预率在组间没有显著差异(p>0.1)。与未接受干预的POD0患者相比,接受POD0干预的患者在下一次随访中没有明显更快地出现。在有和没有潜在青光眼的患者之间,POD0或POD1上IOP峰值大于30mmHg的发生率没有显着差异(总体p=0.2020;青光眼p=0.1238;无青光眼p=0.999)。有青光眼病史的患者与POD1患者相比,POD0患者更不可能接受干预以降低IOP(p=0.999)。结论对患者进行无并发症性白内障手术后的当天难以进行评估。并且很难预测哪些患者可能有术后并发症。我们的研究表明,与POD1相比,POD0患者的管理没有显着变化。外科医生可以期望POD1的视力明显更好,但除此之外,POD0和POD1患者的术后结局相似.外科医生可以为接受简单白内障手术的患者提供POD0就诊的选择。
    Purpose To compare the postoperative outcomes and management of uncomplicated cataract surgery seen on postoperative day 0 (POD0) versus postoperative day one (POD1).  Methods A retrospective cohort study of patients who followed up within 0-14 days of their uncomplicated surgery (current procedural terminology code 66984) from December 2018 to March 2020. Those who had perioperative complications, those who had combined glaucoma filtering surgery as well as other minimally invasive glaucoma surgery (MIGS) procedures, and those who did not complete their first two follow-up visits within 14 days of their surgery were excluded. Visual acuity (VA), intraocular pressure (IOP), post-operative interventions, and complications of the first and second postoperative visits were collected. Results Of the 665 participants studied, the mean (standard deviation) age was 68 (11) years old and 60% were female (n=304) with a mean (SD) pre-op logarithm of the minimum angle of resolution (logMAR) VA of 0.715 (0.625). About one-third (32%) of patients were seen on POD0. Compared to POD1, a higher percent of patients with glaucoma were seen POD0 (23% vs 14%; p = 0.008). The mean VA on POD0 was 0.840 (0.653), which was significantly worse than the mean VA of 0.539 (0.599) on POD1 (p<0.0001). There was no significant difference in VA by the second post-op visit. IOP did not significantly differ between POD0 and POD1 groups at the first post-operative visit. The most common changes in the post-operative drop regimen were related to IOP and inflammation control. The rate of interventions did not significantly differ between groups (p>0.1). Patients who received intervention on POD0 were not seen significantly sooner at the next follow-up visit compared to those seen on POD0 without undergoing an intervention. The incidence of an IOP spike greater than 30mmHg on POD0 or POD1 was not significantly different between patients with and without underlying glaucoma (overall p = 0.2020; with glaucoma p= 0.1238; without glaucoma p=0.999). Those with a history of glaucoma were not more likely to receive intervention to lower IOP on POD0 versus those seen on POD1 (p = 0.999).  Conclusion It can be difficult to evaluate patients the day after their uncomplicated cataract surgery, and it is difficult to predict which patients may have post-operative complications. Our study shows no significant changes in management for patients seen on POD0 compared to POD1. Surgeons can expect significantly better visual acuity on POD1, but otherwise, post-operative outcomes were similar between patients seen on POD0 and those seen on POD1. Surgeons may offer the option of a POD0 visit for patients who underwent uncomplicated cataract surgery.
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  • 文章类型: Case Reports
    最近的文献表明,使用sugammadex逆转神经肌肉阻滞剂(NMBAs)可降低重症肌无力(MG)患者术后肌无力危象(MC)的风险,特别是在胸腺切除术后,但是缺乏关于紧急手术的研究。我们使用sugamadex和新斯的明(与格隆溴铵)的组合成功实现了神经肌肉阻滞(NMB)的术中逆转。然而,无法避免MC,术后第1天需要重新插管。一名65岁的男性,有长期的MG病史,因腹痛出现在急诊科,腹泻,呕吐,发冷,和疲劳三天。腹部计算机断层扫描(CT)扫描显示急性阑尾炎,他在医院第1天接受了腹腔镜阑尾切除术。患者使用小于平均剂量的罗库溴铵进行了快速顺序诱导,成功的全身麻醉,考虑到他的MG历史。在案件结束时,sugammadex,然后是新斯的明/格隆溴铵和随后剂量的sugammadex,与NMB的逆转。患者成功拔管,但术后第1天因高碳酸血症呼吸衰竭需要重新插管。我们对这名MG患者的病例报告产生了两个尚未广泛检查的主题。首先,sugammadex和新斯的明/格隆溴铵的双重治疗可能比NMBA逆转的个体治疗提供显著的临床益处。考虑到它们的作用机制是不同的,特别是在新斯的明/格隆铵之前给药。第二,缺乏接受急诊手术的MG患者的麻醉文献。虽然sugammadex在医学上优化的非紧急手术中一直很有希望,我们在这里讨论了sugammadex在急诊手术中未能预防MC的情况,并探讨了什么可以为患者提供避免术后MC的最佳机会.
    Recent literature suggests that the use of sugammadex for the reversal of neuromuscular blocking agents (NMBAs) reduces the risk of postoperative myasthenic crisis (MC) in patients with myasthenia gravis (MG), particularly after thymectomy, but studies are lacking on emergency surgeries. We achieved successful intraoperative reversal of neuromuscular blockade (NMB) using a combination of sugammadex and neostigmine (with glycopyrrolate). However, MC was not avoided and reintubation was required on postoperative day 1. A 65-year-old male with a longstanding history of MG presented to the emergency department with complaints of abdominal pain, diarrhea, vomiting, chills, and fatigue for three days. A computed tomography (CT) scan of the abdomen showed acute appendicitis, for which he underwent a laparoscopic appendectomy on hospital day 1. The patient received successful general anesthesia with a rapid sequence induction using a smaller than average dose of rocuronium, given his history of MG. At the conclusion of the case, sugammadex followed by neostigmine/glycopyrrolate and a subsequent dose of sugammadex were given, with reversal of NMB. The patient was successfully extubated but required reintubation on postoperative day 1 for hypercapnic respiratory failure. Our case report on this patient with MG yields two topics that have not been extensively examined. First, dual therapy with sugammadex and neostigmine/glycopyrrolate may provide significant clinical benefit over individual therapy for NMBA reversal, given that their mechanisms of action are different and particularly when sugammadex is given prior to neostigmine/glycopyrrolate. Second, anesthesia literature is lacking on MG patients undergoing emergency surgeries. While sugammadex has been promising in medically optimized non-emergent surgeries, we discuss here a case where sugammadex failed to prevent MC in the emergency surgery setting and a look into what may provide patients with the best chance for avoiding postoperative MC.
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