The optimal intermittent time for post-activation potentiation (PAP) training remains uncertain and contentious. This study employed a meta-analysis to systematically evaluate the effect of different intermittent times on PAP in relation to explosive vertical jump height. Relevant literature was sourced from CNKI, Wanfang, VIP, CBM, PubMed, Web of Science, and Google Scholar databases using keywords such as \"postactivation potentiation,\" \"activation enhancement effect,\" \"PAP,\" \"explosive vertical jump,\" \"explosive vertical high jump,\" and \"intermittent time.\" The search covered publications from the inception of each database until June 2024. Studies involving athletes (regardless of sport type) undergoing PAP training were included, with no restrictions on the methods used to induce PAP. Comparative analysis focused on the heights of countermovement jumps (CMJ) and peak ground reaction force (GRF) before and after interventions. The quality of the included studies was assessed using the Cochrane Risk of Bias Tool, and data were analyzed using RevMan5.3. The study included a total of 21 papers with 327 subjects, primarily using the squat as the method of PAP induction. The meta-analysis revealed that intermittent times of 4 min [MD = - 0.03, 95% CI: - 0.04 ~ - 0.01; Z = 2.71, P = 0.007] and 5-8 min [MD = - 0.03, 95% CI: - 0.04 ~ - 0.01; Z = 3.07, P = 0.002] significantly increased the height of explosive vertical CMJs. However, intermittent times of 1-3 min [MD = -0.00, 95% CI: - 0.01 ~ 0.01; Z = 0.38, P = 0.70] and 10-24 min [MD = - 0.01, 95% CI: - 0.02 ~ 0.00; Z = 1.43, P = 0.15] did not show significant effects on CMJ height. These findings indicate that 4-min and 5-8 min intervals significantly enhance CMJ height, while intervals shorter than 4 min or longer than 8 min do not have a significant impact.

UNASSIGNED: This meta-analysis aims to systematically evaluate the impact of blood flow restriction training (BFRT) on muscle activation and post-activation potentiation (PAP) in the upper limbs, to provide guidance for upper limb protocols aiming to enhance explosive strength and activation.
UNASSIGNED: PubMed, CNKI, Web of Science, and EBSCO databases were queried to identify randomized controlled trials (RCTs) investigating the effects of upper limb BFRT on muscle activation and PAP. Inclusion and exclusion criteria were applied using the Cochrane bias risk tool. Literature quality assessment and statistical analysis were conducted using Revman 5.4 and Stata 17.0 software. Sensitivity analysis and funnel plots were utilized to assess result stability and publication bias.
UNASSIGNED: A total of 31 articles involving 484 participants were included in the analysis. Meta-analysis results showed that upper limb BFRT significantly increased muscle iEMG values [SMD = 0.89, 95%CI (0.21, 1.58), p = 0.01]. BFRT had a significant effect on upper limb explosive force [SMD = 0.73, 95%CI (0.41, 1.04), p < 0.00001]. Subgroup analysis based on literature heterogeneity (I 2 = 92%, 80%) showed that exhaustive BFRT significantly decreased upper limb iEMG [SMD = -0.67, 95%CI (-1.25, -0.09), p = 0.01], with exercise modes including maximum output power of bench press [SMD = 1.87, 95%CI (0.22, 3.53), p < 0.0001], exercise intensity of 40%-70% 1RM [SMD = 1.31, 95%CI (0.61, 2.01), p < 0.0001], and pressure intensity of ≥60% AOP [SMD = 0.83, 95%CI (0.43, 1.23), p < 0.0001] reaching maximum effects and statistical significance.
UNASSIGNED: Upper limb BFRT can induce muscle activation and PAP. BFRT with 40%-70% 1RM and ≥60% AOP in the upper limbs is more likely to promote PAP.
UNASSIGNED: http://inplasy.com, identifier INPLASY202430008.

Purpose: This study examined how a low dose of an eccentric-oriented lunge exercise could induce the repeated-bout effect (RBE) and affect the subsequent post-activation performance enhancement (PAPE) in recreational runners. Methods: Twenty male recreational runners (32.1 ± 2.8 years; 173.4 ± 6.1 cm; 73.3 ± 11.5 kg; 57.8 ± 7.2 mL·kg-1·min-1) were divided into control (N = 10) and experimental (N = 10) groups. In the first and fourth weeks, the groups were assessed for jump capacity, dynamic balance, and submaximal running kinematics before and after an incremental shuttle-run test until exhaustion. The experimental group was also submitted to two sessions of the eccentric-oriented lunge exercise (3 sets of 10 repetitions with 2 min of passive recovery) in the second and third weeks. Results: We observed that the first session promoted muscle damage, which was significantly (p < .05) reduced after the second training session, thus indicating an RBE. Meanwhile, there was no effect of the RBE on dynamic balance and submaximal running kinematics in the post-intervention. However, there was a significant increase in countermovement jump height (p = .008) for the experimental group when compared to the control group, although no PAPE was observed. Conclusions: The current results demonstrate that a simple, low-dose eccentric-oriented exercise may induce an RBE, leading to reduced muscle damage and a possibly improved lower limbs\' muscle power in recreational runners. However, the absence of PAPE effects suggests that the RBE may not directly influence the potentiation/fatigue balance after fatiguing running exercises.

The aim was to identify if surface electromyography (sEMG) parameters are indicative of post-activation potentiation (PAP)/post-activation performance enhancement (PAPE), in terms of twitch potentiation and voluntary performance. Three databases were used in April 2024, with the following inclusion criteria: (a) original research, assessed in healthy human adults, and (b) sEMG parameters were measured. The exclusion criteria were (a) studies with no PAP/PAPE protocol and (b) non-randomized control trials. The following data were extracted: study characteristics/demographics, PAP/PAPE protocols, sEMG parameters, twitch/performance outcomes, and study findings. A modified physiotherapy evidence database (PEDro) scale was used for quality assessment. Fifteen randomized controlled trials (RCTs), with a total of 199 subjects, were included. The M-wave amplitude (combined with a twitch torque outcome) was shown to generally be indicative of PAP. The sEMG amplitudes (in some muscles) were found to be indicative of PAPE during ballistic movements, while a small decrease in the MdF (in certain muscles) was shown to reflect PAPE. Changes in the Hmax/Mmax ratio were found to contribute (temporally) to PAP, while the H-reflex amplitude was shown to be neither indicative of PAP nor PAPE. This review provides preliminary findings suggesting that certain sEMG parameters could be indicative of PAP/PAPE. However, due to limited studies, future research is warranted.

The phenomenon of post-activation performance enhancement plays an unidentified role in movement eccentric speed and individual muscle group responses. Therefore, this study aimed to determine whether the loaded front squat (FSq) speed of the eccentric phase would influence the post-activation performance enhancement effect and whether the FSq would elicit similar performance enhancement of knee flexion, knee extension, hip flexion, and hip extension muscles. Twenty resistance-trained handball players performed the FSq under maximum eccentric-concentric speed and 2-s eccentric speed (only the eccentric phase performed), while pre- and post-front squat countermovement jump, knee, and hip isokinetic flexion/extension performance were tested. The FSq conditioning activity was performed in a single set of three repetitions with either 90% (maximum eccentric-concentric speed) or 120% (2-s eccentric speed) of one repetition maximum, and post-performance was measured 4-12 min after the FSq. Athletes randomly changed the FSq eccentric speed and tested the hip or knee isokinetic flexion/extension strength at 180°/s. ANOVA showed that the rate of force development during the jump increased (Cohen d = 0.59-0.77) with no differences between 2-s eccentric and maximum speed eccentric protocols. Isokinetic strength increased after the 2-s eccentric FSq in hip extension (d = 0.76-0.86), knee flexion (d = 0.74-0.88), and hip flexion (d = 0.82), with no differences in knee extension strength. After maximum eccentric-concentric speed, isokinetic strength increased in hip extension (d = 1.25). In conclusion, the FSq conditioning activity enhances hip extensors\' performance more than knee extensors\' performance. Different eccentric types of muscle action during a conditioning activity alter the level of local muscle enhancement.

No study has assessed supramaximal (over 100% 1RM) back squat variations as a potentiating stimulus in collegiate throwers. The purpose of this study was to test the hypothesis that a supramaximal Anderson (bottom-up) quarter squat potentiating stimulus would improve discus throw performance in Division I throwers compared to a dynamic warm-up alone. Nine NCAA division I thrower athletes (age: 20.1±1.4 years; 1RM back squat/body weight: 2.5±0.4 kg) randomly completed two sessions separated by at least 72 hours. One session involved a standardized dynamic warm-up alone (DyWU) followed by three trials of maximal discus throwing. The other session involved a dynamic warm-up with a supramaximal (105% 1RM) Anderson (bottom-up) quarter-squat set of 5 repetitions post activation performance enhancement stimulus (DyWU+PAPE) followed by three trials of maximal discus throwing. A two-way (warm-up strategy x time) ANOVA with repeated measures for each time point was used, with significance set at p< 0.05. There were no significant (p> 0.05) differences between DyWU alone versus DyWU+PAPE stimulus for discus throw distances at either 8 min. (31.7±5.6 vs 30.6±6.5 meters, respectively; d = -0.18), 11 min. (33.4±3.6 vs 31.3±4.7 meters, respectively; d = -0.52), or 14 min. post warm-up (34.1±3.9 vs 32.3±5.3 meters, respectively; d = -0.40). Compared to a dynamic warm-up alone, supramaximal Anderson quarter-squats following a dynamic warm-up had trivial/small to moderate detrimental effects on discus throw performance between 8-14 minutes post stimuli in Division I trained throwers, likely due to excess fatigue/PAPE inhibition.

BACKGROUND: Maximal conditioning contractions (CCs) can lead to the enhancement of evoked-twitch characteristics in human skeletal muscle. This phenomenon is termed post-activation potentiation (PAP). In the knee extensors, PAP is greater in men compared with boys. In adults, the optimal CC duration for PAP is ~ 10 s. We examined child-adult differences in PAP among females and aimed to determine the optimal CC duration in girls and women.
METHODS: Eleven girls (9.3 ± 1.4 years) and 13 women (23.4 ± 2.7 years) participated in this study. Maximal isometric evoked twitches were recorded in the knee extensors before and after 4 maximal CCs of different durations (5, 10, 20, and 30 s), in a random order. PAP was calculated as the percent-change in peak torque (Tpeak) and peak rate of torque development (RTDpeak) after each CC.
RESULTS: There was a group-by-duration interaction (p < 0.001), reflecting greater Tpeak PAP in women compared with girls following 5 and 10 s CCs, and lower RTDpeak PAP in women following the 30 s CC. The 5 and 10 s CCs lead to the greatest Tpeak and RTDpeak PAP amongst the women while there were no differences between CC durations in girls.
CONCLUSIONS: After both a 5 and 10 s CC, women have greater PAP compared with girls. The optimal CC duration for the knee extensors in women appears to be ~ 5-10 s, while CC durations between 5 and 30 s do not appear to affect levels of PAP in girls.

Objective: This study aims to systematically evaluate the effects of blood flow restriction (BFR) training on lower limb muscle activation and post-activation potentiation (PAP) in athletes through a meta-analysis and discuss methods to improve instant muscle strength so as to provide a reference for training in this field. Methods: Randomized controlled trials (RCTs) that examined the impact of BFR training on muscle activation and PAP were gathered through database searches, such as CNKI, Wanfang, Web of Science, PubMed, and others. The Cochrane risk of bias tool was used to include and exclude literature. Quality evaluation and statistical analysis were conducted using ReviewManager 5.3 software, STATA 16.0, and other software programs. The sensitivity analysis and funnel plots were employed to assess result stability and publication bias. Results: In total, 18 literature studies were included with a total of 267 subjects. The meta-analysis showed that BFR could significantly improve the RMS value of lower limb muscles [SMD = 0.98, 95% CI (0.71, 1.24), and p < 0.00001]. BFR had a significant effect on the immediate explosive power of the lower limbs [SMD = 0.28, 95% CI (0.02, 0.53), and p = 0.03], but the heterogeneity was obvious (I 2 = 51%). The subgroup analysis showed that different training methods may be influencing factors that lead to the heterogeneity between studies. The measurement indexes were the counter movement jump (CMJ) [SMD = 0.45, 95% CI (0.20, 0.69), and p = 0.0004], training mode to overcome body weight [SMD = 0.57, 95% CI (0.33, 0.82), and p < 0.00001], and compressive strength of 40%-60% arterial occlusion pressure (AOP) [SMD = 0.57, 95% CI (0.31, 0.83), and p < 0.0001], which reached the maximum effect and was statistically significant. Conclusion: BFR training can induce lower extremity muscle activation and PAP. Combining self-weight training with BFR exercises set at 40%-60% AOP appears to be particularly effective in inducing PAP, especially for enhancing CMJ. Furthermore, combining body-weight training with BFR is considered an effective warm-up method to improve CMJ. Systematic Review Registration: http://inplasy.com, identifier INPLASY2023100087.

The purpose of this study was to investigate the effect of inducing post-activation potentiation (PAP) during prolonged low-frequency force depression (PLFFD) on motor unit (MU) firing rates. In 10 participants, grouped firing rates of 3027 MUs from the tibialis anterior were recorded with tungsten microelectrodes. Baseline MU firing rates at 25% isometric maximal voluntary contraction (MVC) were ∼14 Hz. A 1 min dorsiflexion MVC reduced torque and maximal MU firing rates (36 Hz) by 49% and 52%, respectively. Following task completion, firing rates at 25% of baseline MVC torque and torque in response to electrically evoked (single twitch, 10 Hz and 50 Hz) stimulation were assessed before and after a 5 s MVC (to induce PAP) every 10 min for 60 min. From 10 to 60 min after task completion, the torque ratios (twitch:50 Hz and 10:50 Hz) were depressed (∼30%) relative to baseline (P < 0.001), indicating PLFFD; and firing rates were higher by ∼15% relative to baseline (P < 0.001). This occurred despite recovery of MVC rates (∼99%) and torque (∼95%) by 10 min (P > 0.3). Inducing PAP during PLFFD increased both low to high torque ratios (twitch and 10:50 Hz) by ∼200% and ∼135%, respectively (P < 0.001) and firing rates were ∼18% lower relative to PLFFD rates (P < 0.001), despite a speeding of evoked contractile properties (P = 0.001). Thus, firing rates appear strongly matched to alterations in torque, rather than contractile speed when modified by contractile history, and lower rates during PAP may be a mechanism to mitigate effects of PLFFD. The effect of activation history on contractile function demonstrates acute compensatory responses of motoneuron output. KEY POINTS: Prolonged low frequency force depression (PLFFD) following a sustained 1 min isometric maximal voluntary contraction causes an increase in submaximal mean motor unit (MU) firing rates. Inducing post-activation potentiation (PAP) during PLFFD, however, causes a reduction in mean submaximal MU firing rates to a level below those at baseline. The mean firing rate reduction during PAP occurs despite a speeding of evoked contractile properties and thus firing rates are more strongly matched to alterations in torque, rather than contractile speed when modified by various contractile histories. The reductions in firing rates during PAP may mitigate the effects of PLFFD during voluntary contractions. These results demonstrate that firing rates are highly responsive to opposing influences on the contractile state and can make rapid compensatory rate adjustments dependent on the active state of the muscle.

The purpose of this study was to compare the acute effects of back squat exercise with or without elastic band on countermovement jump performance. Thirteen collegiate male basketball players (age: 20.5 ± 0.9 years; height: 188.5 ± 8.5 cm; body mass: 82.8 ± 12.9 kg) completed 5 familiarization and 4 experimental sessions separated by at least 48 hours. In the experimental sessions, the order of the conditions was randomized so that the participants performed 1 set of 3 repetitions of barbell back squat at 85% of their one-repetition maximum (1-RM), 1 set of 3 repetitions of back squat at 85% 1-RM with 20% variable resistance training (VRT), 30%VRT, or 40%VRT of the total load coming from the elastic band. Countermovement jump performance was assessed before (baseline), 30 seconds, 3 minutes, 6 minutes, and 9 minutes following each condition. Jump height, rate of force development, peak power, and vastus lateralis, vastus medialis, and medial gastrocnemius electromyography data were collected. Compared with the baseline, 30%VRT significantly improved jump height at 3 minutes post-exercise by 1.3 cm (P < 0.001) and 6 minutes post-exercise by 1.2 cm (P = 0.005); 40%VRT significantly improved jump height from 30 seconds up to the 9th minute (1.2 to 1.9 cm, P ≤ 0.036). The superior jump height was also accompanied by improved kinetic and electromyography data. No significant changes were observed in the barbell back squat and 20%VRT conditions. In conclusion, back squat at 85% 1-RM with 40% elastic band resistance led to superior vertical jump performance with an optimal time window of 3 minutes.