背景:经过一段时间的冷漠,合成药物是首选的地方,对植物的生物学方面和生物活性成分负责治疗潜力的兴趣已经被显著地探索。SidacordifoliaL.是一种多年生草本植物,已在印度广泛使用(阿育吠陀,Unani,和Siddha),美国人,以及中国民间医学和草药治疗人类多种疾病的实践。
目的:这篇综述的目的是阐明本土知识,同时阐明四达科迪叶对各种疾病的药物治疗潜力。它还旨在显示与纳米颗粒轮廓有关的相关信息。
方法:在当前的综合研究中,基于网络的搜索是通过使用几个数据库进行的,比如谷歌学者,PubMed,ResearchGate,科学直接,还有Scopus,找出1930年至7月在学术期刊上发表的相关研究工作和数据,2023年,使用此处列出的单个或组合关键字。
结果:50多种化学成分,包括喹唑啉和苯乙胺生物碱,黄酮,黄酮醇,植物甾醇,脂肪酸,等。,据报道,在健康植物的不同部位都有发现。除了传统的主张和药理学方面,还描述了几种已上市的草药配方和已授权的专利。
结论:一些体外和体内研究验证了S.cordifolia作为抗炎,抗菌,抗真菌药,抗原生动物,驱虫药,抗癌,抗溃疡,心脏保护,低血糖,等。agent.很少有专利也与S.cordifolia有关,并且还需要开展更多的研究工作,才能将其用作抗病毒剂和其他新药发现分子。
BACKGROUND: After a period of prolonged indifference, where synthetic drugs were preferred, interest in the biological aspects and bioactive ingredients of plants accountable for therapeutic potential has been explored eminently. Sida cordifolia L. is a perennial herb that has been widely utilized in Indian (Ayurveda, Unani, and Siddha), American, and Chinese folk medicine and herbalism practice for curing a wide range of ailments in human beings.
OBJECTIVE: The goal of this review is to elucidate indigenous knowledge parallelly with the pharmacotherapeutics potential of Sida cordifolia L. against various diseases. It is also intended to display pertinent information related to nanoparticle profiling.
METHODS: In the current comprehensive study, web-based searches were performed by using several databases, such as Google Scholar, PubMed, ResearchGate, Science Direct, and Scopus, to figure out relevant research work and data published in academic journals from 1930 to July, 2023 using single or combination of keywords listed herewith.
RESULTS: More than 50 chemical constituents, including quinazoline and phenethylamine alkaloids, flavones, flavonol, phytosterol, fatty acids, etc., were reported to be found in different parts of healthy plants. Apart from traditional claims and pharmacological aspects, several marketed herbal formulations and granted patents were also described.
CONCLUSIONS: Several in-vitro and in-vivo studies validated the usage of S. cordifolia as antiinflammatory, antibacterial, antifungal, antiprotozoal, anthelmintic, anticancer, antiulcer, cardioprotective, hypoglycemic, etc. agent. Few patents are also related to S. cordifolia, and more research work needs to be carried out for its potential granted to use as an antiviral agent and other new drug discovery molecules.