Periodontology

牙周学
  • 文章类型: Case Reports
    内周病变是涉及牙髓组织和牙周组织的病变。牙髓的细菌感染可以通过副管扩散到分叉区,对分叉区域造成损害。通过皮瓣手术进行再生疗法具有很好的成功,并且在I级和II级分叉受累的情况下进行。脱矿质冻干同种异体骨移植物(DFDBA)是具有骨诱导和骨传导能力的再生材料。它具有成功治疗骨缺损的优点。生物牙本质是一种用于直接盖髓的试剂,根穿孔和分叉修复,和apexification。它可以结合并进入牙本质小管,并与牙本质产生互锁晶体。该病例报告介绍了通过使用DFDBA和Biodentine作为再生材料并进行6个月的随访来治疗源自子宫内病变的II级分叉受累。
    Endo-perio lesions are lesions involving pulp tissue with periodontal tissue. The bacterial infection of the pulp can spread to the furcation area through the accessory canal, causing damage to the furcation area. Regeneration therapy has good success when performed with flap surgery and is performed in cases of Grades I and II furcation involvement. Demineralized freeze-dried bone allograft (DFDBA) is a regenerating material that has osteoinductive and osteoconductive abilities. It has the advantage of successful treatment of bone defects. Biodentine is an agent used for direct pulp capping, root perforation and furcation repair, and apexification. It can bind and enter the dentinal tubules and create interlocking crystals with dentin. This case report presents the treatment of furcation involvement Grade II originating from endo-perio lesions by using DFDBA and Biodentine as regeneration materials with 6 months of follow-up.
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  • 文章类型: Journal Article
    计算牙本质和/或次生牙骨质中的生长层被广泛用于野生哺乳动物的年龄确定,但是牙齿组织的结构和矿化程度的潜在季节性变化尚未得到很好的表征。我们在聚甲基丙烯酸甲酯(PMMA)中嵌入了来自12岁雌性斯瓦尔巴德驯鹿(Rangifertarandusplatyrhynchus)的第一(m1)和第二(m2)下颌恒磨牙,制备的涂覆有蒸发碳的切割和抛光表面,并在扫描电子显微镜(BSE-SEM)中使用20kV背散射电子成像来研究取决于微米和亚微米尺度的矿化程度的牙齿组织结构的方面。BSE-SEM揭示了次生牙骨质与原发性和继发性牙本质中生长层(环状物)的矿物质含量之间的差异,后者,顺便说一句,仍在m1死亡时形成。在活跃的并置阶段,牙骨质中形成了较少矿化组织的宽带。薄,冬季生长放缓时,由现有组织的成熟矿化形成的致密带。这种成熟模拟了在板层骨和关节软骨中看到的过程。反对以前的建议,有证据表明,在整个生命过程中,继发性牙骨质的大量吸收和修复以及牙本质的形成。次生牙本质由矿物质含量分层,如牙骨质。在皇冠上,这主要是管状牙本质,具有明显的珠状牙本质层。在下牙室和根部,它基本上没有小管。在m2根尖区域的水泥-牙本质交界处发现的大量非矿化空间代表两个组织之间的Hertwig上皮根鞘(HERS)或Malassez上皮其余部分(ERM)的夹杂物。以前仅在Muridae中发现的现象。导致驯鹿牙齿组织中增量线(环形)形成的解剖学变化,在这里首次在微米级被识别,可能在大多数(如果不是所有)生活在季节性环境中的长寿哺乳动物物种中很常见。
    Counting growth layers in dentine and/or secondary cementum is widely used for age determination in wild mammals but the underlying seasonal changes in the structure and degree of mineralisation of dental tissue have not been well characterised. We embedded first (m1) and second (m2) mandibular permanent molar teeth from a 12-year-old female Svalbard reindeer (Rangifer tarandus platyrhynchus) in PolyMethylMethAcrylate (PMMA), prepared cut and polished surfaces coated with evaporated carbon and used 20 kV back-scattered electron imaging in a scanning electron microscope (BSE-SEM) to study aspects of dental tissue structure which depend on the degree of mineralisation at the micron and sub-micron scale. BSE-SEM revealed differences between the mineral content of growth layers (annulations) in the secondary cementum and the primary and secondary dentine, the latter, incidentally, still forming at death in m1. Wide bands of less well mineralised tissue formed in the cementum during active appositional phases. Thin, denser bands formed by maturation-mineralisation of existing tissue when growth slowed in winter. This maturation mimics the processes seen in lamellar bone and articular cartilage. Counter to previous suggestions, there was evidence of substantial resorption and repair of the secondary cementum and of formation of dentine throughout life. Secondary dentine is layered by mineral content like cementum. In the crown, this was mainly tubular dentine with well-marked interglobular dentine layers. In the lower pulp chamber and root, it was largely without tubules. Substantial non-mineralised spaces found at the cement-dentine junction in the root apical regions in m2 represent inclusions of the Hertwig\'s Epithelial Root Sheath (HERS) or the Epithelial Rests of Malassez (ERM) between the two tissues, a phenomenon which has previously only been identified in Muridae. The anatomical changes which result in the formation of the incremental lines (annulations) in dental tissues of reindeer, identified here for the first time at the micrometre level, are likely to be common across most if not all long-lived species of mammals living in seasonal environments.
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  • 文章类型: Journal Article
    背景技术牙周炎是一种复杂的病症,其受到涉及宿主和细菌菌斑之间的相互作用的各种因素的影响。牙龈卟啉单胞菌,厌氧革兰氏阴性细菌,通常与牙周病有关。目的本研究旨在检查被诊断为慢性牙周炎(CP)的个体与没有牙周病临床指征的个体中牙龈卟啉单胞菌的发生。方法本研究招募诊断为CP的患者(包括重度和中度病例)和没有任何牙周病征象的个体。使用刮匙从牙龈袋中收集样品,然后进行厌氧培养。结果一组30例患者,分为中度和重度CP,以及30名健康个体作为对照,进行了检查。在患有CP的个体中,在23例(78%)中发现了牙龈卟啉单胞菌,而在健康的个体中,患病率为10(34%).与健康受试者相比,牙周病患者中牙龈卟啉单胞菌的存在明显更高。比率为23(78%)与10(34%),分别。结论牙龈卟啉单胞菌常见于有牙周病的患者以及无牙周病的患者。虽然数量较少。因此,牙龈卟啉单胞菌的存在增加了患牙周病的可能性,可能被认为是引发牙周病的重要潜在因素。
    Introduction Periodontitis is a complex condition influenced by various factors involving interactions between the host and bacterial plaque. Porphyromonas gingivalis, an anaerobic gram-negative bacterium, is commonly linked with periodontal disease. Aim This study aimed to examine the occurrence of P. gingivalis in individuals diagnosed with chronic periodontitis (CP) compared to those who show no clinical indications of periodontal disease. Methodology Patients diagnosed with CP (including both severe and moderate cases) and individuals without any signs of periodontal disease were recruited for this study. Samples were collected from the gingival pockets using curettes and were subsequently subjected to anaerobic culturing. Results A group of 30 patients, divided into moderate and severe CP, along with 30 healthy individuals serving as controls, were examined. In individuals with CP, P. gingivalis was found in 23 (78%) of cases, while in healthy individuals, the prevalence was 10 (34%). The presence of P. gingivalis was notably higher in those with periodontal diseases compared to healthy subjects, with rates of 23 (78%) vs. 10 (34%), respectively. Conclusion P. gingivalis is frequently found in individuals with periodontal diseases as well as in those without such conditions, albeit in smaller quantities. Consequently, the existence of P. gingivalis raises the probability of developing periodontal disease and may be regarded as a notable potential contributor to its initiation.
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  • 文章类型: Journal Article
    背景:矿物质代谢对于骨骼和牙列的硬组织的正常发育至关重要。牙槽骨复合体包括以下4种矿化组织:牙釉质,牙本质,牙骨质,和牙槽骨。这些组织的发育过程受到遗传性疾病的影响,这些疾病会破坏磷酸盐和焦磷酸盐的稳态,尽管表现与骨骼中的不同。
    方法:作者讨论了实验和比较分析的原始数据,并回顾了描述遗传性磷酸盐和焦磷酸盐疾病对牙齿组织影响的文章。特别强调这些疾病的新治疗方法如何影响受影响患者的口腔健康和牙科治疗。
    结果:磷酸盐和焦磷酸盐代谢紊乱可导致软组织矿化减少(低矿化)或不适当(异位)钙化。X连锁低磷酸盐血症和高磷酸盐血症家族性肿瘤钙质沉着症中磷酸盐水平的破坏以及低磷酸盐血症中的焦磷酸盐水平的破坏和婴儿期的全身性动脉钙化会导致牙齿矿化缺陷。传统上,很少有选择来改善这些疾病引起的牙齿健康问题。新的抗体和酶替代疗法为改善受影响患者的口腔健康带来了可能性。
    结论:过去20年的研究以指数方式扩展了对矿物质代谢的理解,并为矿化障碍带来了新的治疗方法。新实施和新兴的治疗策略会影响牙槽骨复合体,并与牙科治疗必须考虑的口腔保健方面相互作用。临床试验设计,和多学科护理团队的协调。
    BACKGROUND: Mineral metabolism is critical for proper development of hard tissues of the skeleton and dentition. The dentoalveolar complex includes the following 4 mineralized tissues: enamel, dentin, cementum, and alveolar bone. Developmental processes of these tissues are affected by inherited disorders that disrupt phosphate and pyrophosphate homeostasis, although manifestations are distinct from those in the skeleton.
    METHODS: The authors discuss original data from experiments and comparative analyses and review articles describing effects of inherited phosphate and pyrophosphate disorders on dental tissues. A particular emphasis is placed on how new therapeutic approaches for these conditions may affect oral health and dental treatments of affected patients.
    RESULTS: Disorders of phosphate and pyrophosphate metabolism can lead to reduced mineralization (hypomineralization) or inappropriate (ectopic) calcification of soft tissues. Disruptions in phosphate levels in X-linked hypophosphatemia and hyperphosphatemic familial tumoral calcinosis and disruptions in pyrophosphate levels in hypophosphatasia and generalized arterial calcification of infancy contribute to dental mineralization defects. Traditionally, there have been few options to ameliorate dental health problems arising from these conditions. New antibody and enzyme replacement therapies bring possibilities to improve oral health in affected patients.
    CONCLUSIONS: Research over the past 2 decades has exponentially expanded the understanding of mineral metabolism, and has led to novel treatments for mineralization disorders. Newly implemented and emerging therapeutic strategies affect the dentoalveolar complex and interact with aspects of oral health care that must be considered for dental treatment, clinical trial design, and coordination of multidisciplinary care teams.
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  • 文章类型: Journal Article
    The masticatory organ is at the center of dental practice. Tooth loss, regarded as an organ failure, is a core dispute in our profession, as it more often than not does not happen spon-taneously but is influenced by the dentist\'s treatment plan. Despite the prosthetic possibili-ties of tooth replacement, efforts should be made to preserve as many teeth as possible. Decisions between tooth preservation and extraction are complex and have far-reaching consequences. This article discusses this problem using a clinical case study of a 43-year-old female patient with pronounced localized periodontitis. After a comprehensive diagnosis and treatment planning, a daring regenerative therapy was carried out to try to preserve the tooth. The case shows that even seemingly hopeless teeth can be successfully treated syn-chronously using modern therapeutic approaches. Initial literature data supports the possi-bility of preserving severely compromised teeth in the long term in compliant patients. An integrative treatment approach based on individual patient factors and modern regenerative techniques may well be a viable alternative to tooth extraction and prosthetic restoration, albeit not inexpensive and uncomplicated. This communication emphasizes the need for precise diagnostics, a comprehensive treatment plan, and honest communication with pa-tients about the prospects of success and possible risks, and highlights the strengths of con-sistent tooth preservation.
    Das Kauorgan steht im Mittelpunkt der zahnärztlichen Praxis. Zahnverlust wird als Organver-sagen betrachtet und stellt ein bedeutendes Problem dar. Trotz prothetischer Möglichkeiten sollte der Erhalt möglichst vieler Zähne angestrebt werden. Entscheidungen zwischen Zahn-erhalt und Extraktion sind komplex und haben weitreichende Folgen. Dieser Artikel behan-delt das Thema anhand eines klinischen Falls einer 43-jährigen Patientin mit ausgeprägter lokalisierter Parodontitis. Nach umfassender Diagnose und Behandlungsplanung wurde eine regenerative Therapie durchgeführt, um den Zahn zu erhalten. Der Fall zeigt, dass auch scheinbar hoffnungslose Zähne mit modernen Therapiemethoden bei zu guter Mundhygiene motivierbaren Patienten erfolgreich behandelt werden können. Erste Literaturdaten unter-stützen die Möglichkeit, stark beeinträchtigte Zähne langfristig zu erhalten. Ein integrativer Behandlungsansatz, basierend auf individuellen Patientenfaktoren und modernen Regenera-tionstechniken, kann eine Alternative zur Extraktion und prothetischen Versorgung sein, ob-wohl er kostspielig und kompliziert ist. Dieser Artikel betont die Notwendigkeit präziser Di-agnostik, umfassender Behandlungspläne und ehrlicher Kommunikation mit den Patienten über Erfolgsaussichten und Risiken sowie die Stärken des konsequenten Zahnerhalts.
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  • 文章类型: Journal Article
    The pathological teeth migrations require correct multidisciplinary treatment which consists of periodontal surgery associated with early or late orthodontic treatment. The aim of this study was to know which of the two orthodontic treatments would have a better periodontal response.
    Two parameters, radiological (the height of the alveolar bone) and clinical (the depth of the periodontal pocket), were used to meet the objective of this work. Eighteen patients received early orthodontic treatment (straight wire appliance) after periodontal flap debridement surgery and eighteen others late orthodontic treatment (straight wire appliance).
    The results showed the absence of significant difference between the two early and late orthodontic treatments after periodontal flap debridement surgery.
    Orthodontic treatment can be started early seven to ten days after periodontal surgery.
    Les migrations dentaires pathologiques exigent un traitement pluridisciplinaire correct qui consiste en une chirurgie parodontale associée à un traitement orthodontique précoce ou tardif. Le but de cette étude était de connaître lequel des deux traitements orthodontiques aurait une meilleure réponse parodontale.
    Deux paramètres, radiologique (la hauteur du défaut osseux) et clinique (la profondeur de la poche parodontale), ont été utilisés afin de répondre à l’objectif de ce travail. Dix-huit patients ont reçu, après la chirurgie parodontale par un lambeau d’assainissement, un traitement orthodontique précoce (technique d’arc droit) et dix-huit autres un traitement orthodontique tardif (technique d’arc droit).
    Les résultats ont montré l’absence de différence significative entre les deux traitements orthodontiques, précoce et tardif, après la chirurgie parodontale par un lambeau d’assainissement.
    Le traitement orthodontique peut débuter précocement dès sept à dix jours après la chirurgie parodontale.
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  • 文章类型: Journal Article
    目的:更新能力和学习成果及其评估,培养当代牙周病专家的教育方法和教育质量保证,包括2018年牙周和种植体周围疾病和病症分类(以下简称2018年分类)和欧洲牙周病联合会(EFP)临床实践指南(CPG)的影响。
    方法:通过科学数据库和搜索欧洲高等教育政策来收集证据。此外,设计了两项调查,并发送给项目主管和毕业生。
    结果:项目主管报告说,课程定期进行调整,以纳入诊断方面的进步,分类,治疗指南和临床技术,包括2018年分类和EFPCPG。毕业生积极评价他们的整体培训,尽管对粘膜牙龈和与牙种植相关的外科手术的培训满意度有限。传统的教育方法,如说教讲座,仍然普遍受雇,但它们现在通常与更具互动性的方法相关联,例如基于案例的研讨会以及基于问题和基于模拟的学习。对能力/学习成果的评估应采用多种评估方法。
    结论:提出了牙周病专科培训的能力和学习成果的更新,包括2018年分类和CPG的知识和实际应用。在欧洲一级,协调牙周病的专家培训是一个关键问题。
    OBJECTIVE: To update the competences and learning outcomes and their evaluation, educational methods and education quality assurance for the training of contemporary specialists in periodontology, including the impact of the 2018 Classification of Periodontal and Peri-implant Diseases and Conditions (2018 Classification hereafter) and the European Federation of Periodontology (EFP) Clinical Practice Guidelines (CPGs).
    METHODS: Evidence was gathered through scientific databases and by searching for European policies on higher education. In addition, two surveys were designed and sent to program directors and graduates.
    RESULTS: Program directors reported that curricula were periodically adapted to incorporate advances in diagnosis, classification, treatment guidelines and clinical techniques, including the 2018 Classification and the EFP CPGs. Graduates evaluated their overall training positively, although satisfaction was limited for training in mucogingival and surgical procedures related to dental implants. Traditional educational methods, such as didactic lectures, are still commonly employed, but they are now often associated with more interactive methods such as case-based seminars and problem-based and simulation-based learning. The evaluation of competences/learning outcomes should employ multiple methods of assessment.
    CONCLUSIONS: An update of competences and learning outcomes of specialist training in periodontology is proposed, including knowledge and practical application of the 2018 Classification and CPGs. Harmonizing specialist training in periodontology is a critical issue at the European level.
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  • 文章类型: Journal Article
    在粘膜类天疱疮伴牙龈表达(gMMP)的情况下,尽管经过医学治疗,牙龈的完全愈合通常无法实现。因此,患者口腔舒适度受损。牙周微生物失调,由于缺乏与持续牙龈疼痛相关的口腔卫生,免疫病理机制能否持续存在。这项研究的主要目的是表征gMMP患者的龈下微生物群,并强调微生物数据和临床数据之间的潜在联系。
    收集15例gMMP患者的龈下生物膜,是否接受药物治疗,但没有接受牙周治疗.记录通常的临床牙周参数。通过聚合酶链反应定量分析生物膜。使用卡方或Fischer精确检验评估严重糜烂性牙龈炎和严重牙周炎的危险因素。
    无论患者的医疗和牙周状况如何,结果显示存在三个主要的牙周病群落,消生菌.第一个包括连翘单纳菌,微生物肽链球菌,具核梭杆菌,和直肌弯曲杆菌,在100%的患者中发现,第二个富含Dinticola密螺旋体60%,第三个富含牙龈卟啉单胞菌和中间Prevotella26%。此外,gMMP的持续时间与糜烂性牙龈炎的严重程度之间存在显着正相关(p=0.009),和深牙周组织的损失(p=0.04)。
    这项初步研究表明gMMP患者牙周风险较高。病理过程,一方面是自身免疫,另一方面是斑块诱导,可以互相放大。因此,牙周治疗的应用与医学治疗并行是必要的。然而,需要进一步的对照研究来验证和补充这些初步结果.
    UNASSIGNED: In the case of mucous membrane pemphigoid with gingival expression (gMMP), the complete healing of the gingiva is generally not achieved despite medical treatment. Therefore, patients\' oral comfort is impaired. The dysbiotic periodontal microbiota, generated by a lack of oral hygiene associated with persistent gingival pain, could the immunopathological mechanism to persist. The main objective of this study was to characterize the subgingival microbiota of the gMMP patients, and to highlight a potential link between this microbiological data and the clinical data.
    UNASSIGNED: Subgingival biofilm was collected from 15 gMMP patients, medically treated or not, but not receiving periodontal treatment. The usual clinical periodontal parameters were recorded. The biofilm was analyzed by polymerase chain reaction quantitative. The risk factors of severe erosive gingivitis and severe periodontitis were assessed using Chi-square or Fischer\'s exact test were used.
    UNASSIGNED: Whatever the medical and periodontal conditions of the patients, the results showed the existence of three main communities of periodontopathic, dysbiotic bacteria. The first including Tannnerella forsythia, Peptostreptococcus micros, Fusobacterium nucleatum, and Campylobacter rectus, was found in 100% of the patients, the second enriched with Treponema denticola in 60% and the third enriched with Porphyromonas gingivalis and Prevotella intermedia in 26%. Furthermore, there was a significant positive link between the duration of gMMP and the severity of erosive gingivitis (p = 0.009), and the loss of deep periodontal tissue (p = 0.04).
    UNASSIGNED: This pilot study suggests a high periodontal risk in gMMP patients. The pathological processes, autoimmune on the one hand and plaque-induced on the other, may amplify each other. The application of periodontal therapy is therefore necessary in parallel with medical treatment. Nevertheless, further controlled studies are required to validate and complement these preliminary results.
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  • 文章类型: Case Reports
    近年来,牙科和牙周诊断的重大进展为改善护理铺平了道路。在可用的方法中,激光荧光(LF)是一种有前途的方法。该病例报告探讨了在生物膜引起的牙龈炎的非手术治疗中使用405nm二极管激光作为诊断工具。以及它在诊断修复体和龋齿的日常实践中的应用。包括一名24岁的男性患者和一名21岁的女性患者。405nm二极管激光器(SmartM,Lasotronix,波兰)用作尖端直径为8毫米的诊断工具。万一有,405nm二极管激光的利用增强了患者感知斑块和结石的存在和程度的能力,在动机和教育有关牙龈上牙生物膜控制和它协助操作者在精确定位牙菌斑和结石,从而实现更有效的机械清创并最终改善治疗结果。在第二种情况下,激光的使用有助于检测有缺陷的复合填充物,有助于为操作者提供准确的诊断,并与患者进行有效的沟通,以了解是否需要重新治疗。这项研究说明了相对较新的405nm二极管激光器作为牙周患者日常管理和日常实践中牙齿填充物缺陷检测的有前途的诊断工具的潜力。
    In recent years, significant advancements in dental and periodontal diagnostics have paved the way for improved care. Among the available approaches, laser fluorescence (LF) is a promising method. This case report explores the utilization of a 405 nm diode laser as a diagnostic tool in the non-surgical treatment of biofilm-induced gingivitis, as well as its application in routine daily practice for diagnosing restorations and dental caries. A 24-year-old male patient and a 21-year-old female patient were included. A 405 nm diode laser (Smart M, Lasotronix, Poland) was used as a diagnostic tool with a tip diameter of 8 mm. In case one, the utilization of the 405 nm diode laser enhanced the patient\'s ability to perceive the presence and extent of plaque and calculus, aiding in motivation and education regarding supra-gingival dental biofilm control and it assisted the operator in precisely localizing plaque and calculus, thereby enabling more effective mechanical debridement and ultimately improving treatment outcomes. In the second case, the utilization of the laser facilitated the detection of defective composite fillings aiding in both accurate diagnosis for the operator and effective communication with the patient regarding the need for re-treatment. This study illustrates the potential of the relatively new 405 nm diode laser as a promising diagnostic tool in the daily management of periodontal patients and the detection of defective dental fillings in daily practice.
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  • 文章类型: Journal Article
    背景:牙周病是一种表现为炎症的感染性综合征。射线照相评估是临床评估的重要补充,但存在局限性,例如无法评估组织炎症。在临床实践中考虑新的探索方法似乎至关重要。牙周组织的超声检查可以使牙周结构可视化并检测牙周疾病(牙周袋测量和组织内炎症的存在)成为可能。临床创新报告:专门开发了一种超声探头来探索牙周组织。本临床创新报告的目的是介绍该设备并揭示其潜力。
    结论:使用超声的各种直接优势:无疼痛,没有出血,更快的执行时间,以及无需再次探查患者即可重播的图像记录。口袋深度的超声测量似乎与通过手动探测获得的测量一样可靠且可重复。组织厚度测量和组织内炎症的检测。
    结论:超声检查似乎具有广泛的适应症。鉴于超声成像作为辅助诊断的主要进步,需要进一步的研究来验证这些要素并阐明超声成像在牙科中的潜在应用领域.
    BACKGROUND: Periodontal disease is an infectious syndrome presenting inflammatory aspects. Radiographic evaluation is an essential complement to clinical assessment but has limitations such as the impossibility of assessing tissue inflammation. It seems essential to consider new exploration methods in clinical practice. Ultrasound of periodontal tissues could make it possible to visualize periodontal structures and detect periodontal diseases (periodontal pocket measurement and the presence of intra-tissue inflammation). Clinical Innovation Report: An ultrasound probe has been specially developed to explore periodontal tissues. The objective of this clinical innovation report is to present this device and expose its potential.
    CONCLUSIONS: Various immediate advantages favor using ultrasound: no pain, no bleeding, faster execution time, and an image recording that can be replayed without having to probe the patient again. Ultrasound measurements of pocket depth appear to be as reliable and reproducible as those obtained by manual probing, as do tissue thickness measurements and the detection of intra-tissue inflammation.
    CONCLUSIONS: Ultrasound seems to have a broad spectrum of indications. Given the major advances offered by ultrasound imaging as a complementary aid to diagnosis, additional studies are necessary to validate these elements and clarify the potential field of application of ultrasound imaging in dentistry.
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