Pathoanatomy

病理解剖学
  • 文章类型: Journal Article
    背景:最近基于3DCT重建的病理解剖学研究对AO/OTA分类的有效性提出了质疑,因为它不能反映现实,需要修订。这些3DCT研究,然而,不允许分析所有细节。因此,我们利用尸检标本分析股骨粗隆间骨折的病理解剖。
    方法:来自解剖学研究所的收藏,作者获得了16例股骨转子周围骨折并在受伤后30天内死亡的髋关节标本,所有这些都有受伤髋部的前后位X光片。主要碎片的数量和它们的形状,研究了主要断裂线的走向。
    结果:三个主要碎片(近端头颈部碎片,远端骨干碎片和后部扁平碎片),由三种类型的骨折线(主要,第二系和第三系)被确定。主线将近端碎片(头部和颈部)与远端骨干碎片分开。二次骨折线将后部扁平碎片与远端骨干碎片分开。第三级骨折线将后部碎片分为两部分。骨折不稳定的一个关键因素是后皮质的缺损,这取决于后部碎片的大小和形状。小转子和邻近皮质的撕脱导致内侧骨折线的不稳定构型。而在外侧,大的后部碎片削弱了转子外侧壁。
    结论:与最近的CT研究一致,这种病理解剖学研究变化的发现,在许多方面,传统的股骨转子骨折的病理解剖和分类的观点,并介绍了三个概念,而不是传统的四个,主要碎片。
    BACKGROUND: Recent pathoanatomic studies based on 3D CT reconstructions have questioned validity of AO/OTA classification because it does not reflect the reality and requires revision. These 3D CT studies, however, do not allow analysis of all details. Therefore, we have exploited the possibility to analyze the pathoanatomy of pertrochanteric fractures on postmortem specimens.
    METHODS: From the collection of the Institute of Anatomy, the authors obtained 16 specimens of hip joints of individuals who had sustained a pertrochanteric fracture and died within 30 days of the injury, with anteroposterior radiographs of the injured hip available in all of them. The number of major fragments and their shape, and the courses of the main fracture lines were studied.
    RESULTS: Three major fragments (a proximal head and neck fragment, a distal diaphyseal fragment and a posterior flat fragment), separated by three types of fracture lines (primary, secondary and tertiary lines) were identified. The primary line separated the proximal fragment (head and neck) from the distal diaphyseal fragment. The secondary fracture line separated the posterior flat fragment from the distal diaphyseal fragment. The tertiary fracture line split the posterior fragment into two parts. A key factor for fracture instability is the defect of the posterior cortex, which depends on the size and shape of the posterior fragment. Avulsion of the lesser trochanter and the adjacent cortex results in an unstable configuration of fracture lines on the medial side, while on the lateral side a large posterior fragment weakens the lateral trochanteric wall.
    CONCLUSIONS: In agreement with recent CT studies, the findings of this pathoanatomical study change, in a number of aspects, the traditional view of the pathoanatomy and classification of pertrochanteric fractures, and introduces the concept of three, instead of the traditional four, main fragments.
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  • 文章类型: Journal Article
    背景:迄今为止,尚未发表关于AC关节损伤合并肩胛骨骨折的详细研究。这项研究的目的是描述这些损伤的病理解剖学。
    方法:在20022020年期间的一系列519例成年患者的肩胛骨骨折中,我们确定了总共20例(3.9%)与AC脱位相关的病例。该组包括17名男性和3名女性,平均年龄为49岁(范围,2178).肩关节的X线照片,然后进行CT检查,包括3D重建,在所有患者中进行。该文件允许评估肩胛骨骨折类型和AC关节损伤类型。
    结果:AC脱位伴单纯肩胛骨骨折15例(喙突基底骨折7例,4个肩峰或外侧脊柱骨折,2例肩胛骨骨折,上关节盂骨折1例,下关节盂骨折1例)。在5例中,AC脱位伴有多发性或复杂性肩胛骨骨折(一旦合并喙突骨折和肩胛骨外侧骨折,一旦结合了上关节盂和肩峰的骨折,复杂关节内骨折2例,肩胸分离1例)。
    结论:AC脱位是伴随肩胛骨骨折的相对少见的损伤。最常见于喙突骨折,肩峰/外侧脊柱或上关节盂。在肩胛骨颈骨折中未记录到AC脱位的病例。
    BACKGROUND: No detailed study dealing with an injury to the AC joint in combination with scapular fractures has been published to date. The aim of this study is to describe pathoanatomy of these injuries.
    METHODS: In a series of 519 scapular fractures in adult patients from the period of 20022020 we identified a total of 20 (3.9%) cases associated with AC dislocation. The group comprised 17 men and 3 women with the mean age of 49 years (range, 2178). Radiographs of the shoulder joint followed by CT examination, including 3D reconstructions, were performed in all patients. This documentation allowed assessment of the scapular fracture pattern and type of injury to the AC joint.
    RESULTS: AC dislocation was associated with a simple scapular fracture in 15 cases (7 fractures of the coracoid base, 4 fractures of the acromion or the lateral spine, 2 fractures of the scapular body, 1 fracture of the superior and 1 fracture of the inferior glenoid). In 5 cases AC dislocation accompanied multiple or complex scapular fractures (once a combination of a coracoid fracture and a fracture of the lateral scapular spine, once a combination of a fracture of the superior glenoid and of the acromion, 2 cases of a complex intraarticular fracture and 1 case of scapulothoracic dissociation).
    CONCLUSIONS: AC dislocation is relatively infrequent injury accompanying scapular fractures. It is most commonly associated with fractures of coracoid, acromion/lateral spine or superior glenoid. No case of AC dislocation was recorded in a fracture of the scapular neck.
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  • 文章类型: Journal Article
    过去16年进行髋关节镜检查的次数明显增加,主要是股髋臼撞击(FAI)的治疗。对FAI病理解剖学的见解,和高水平的证据支持关节镜在FAI治疗中的临床有效性,助长了这一趋势。与清创术相比,关节镜下修复唇缘撕裂可能有更好的效果。现在有新的证据支持重建的选择,修复是不可能的。在进行门静脉囊切开术以方便进入的情况下,现在的数据支持在术后不稳定风险增加的选择性病例中关闭胶囊.术前计划是FAI骨矫正手术不可或缺的组成部分,这已经演变为包括计算机计划的切除。然而,这样做的好处仍然存在争议。髋关节不稳定现在被广泛接受,诊断标准和治疗方法日益完善。不稳定性也可以与FAI一起存在或作为FAI治疗的结果而发展。在这个注释中,我们概述了当前与FAI髋关节镜检查决策相关的主要争议。引用本文:骨关节J2022;104-B(5):532-540。
    There has been a marked increase in the number of hip arthroscopies performed over the past 16 years, primarily in the management of femoroacetabular impingement (FAI). Insights into the pathoanatomy of FAI, and high-level evidence supporting the clinical effectiveness of arthroscopy in the management of FAI, have fuelled this trend. Arthroscopic management of labral tears with repair may have superior results compared with debridement, and there is now emerging evidence to support reconstructive options where repair is not possible. In situations where an interportal capsulotomy is performed to facilitate access, data now support closure of the capsule in selective cases where there is an increased risk of postoperative instability. Preoperative planning is an integral component of bony corrective surgery in FAI, and this has evolved to include computer-planned resection. However, the benefit of this remains controversial. Hip instability is now widely accepted, and diagnostic criteria and treatment are becoming increasingly refined. Instability can also be present with FAI or develop as a result of FAI treatment. In this annotation, we outline major current controversies relating to decision-making in hip arthroscopy for FAI. Cite this article: Bone Joint J 2022;104-B(5):532-540.
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  • 文章类型: Journal Article
    公认的导致髌骨不稳定的解剖变异包括髌骨和滑车发育不良。伸肌机制相对于滑车的横向化通常被认为是一个促成因素;然而,关于这导致不稳定的程度以及应该如何衡量,仍然存在争议。由于胫骨结节-滑车沟(TT-TG)是评估伸肌机构偏侧化的最常见成像测量之一,重要的是要了解它的优点和缺点。在解释TT-TG值时需要小心,因为它会受到许多因素的影响。中介胫骨结节截骨术有时用于纠正TT-TG,但可能无法真正解决潜在的解剖学问题。这篇综述旨在确定TT-TG距离是否充分总结了病理解剖学,如果这有助于髌骨不稳定的手术计划。引用这篇文章:BoneJtOpen2022;3(3):268-274。
    Recognized anatomic variations that lead to patella instability include patella alta and trochlea dysplasia. Lateralization of the extensor mechanism relative to the trochlea is often considered to be a contributing factor; however, controversy remains as to the degree this contributes to instability and how this should be measured. As the tibial tuberosity-trochlear groove (TT-TG) is one of most common imaging measurements to assess lateralization of the extensor mechanism, it is important to understand its strengths and weaknesses. Care needs to be taken while interpreting the TT-TG value as it is affected by many factors. Medializing tibial tubercle osteotomy is sometimes used to correct the TT-TG, but may not truly address the underlying anatomical problem. This review set out to determine whether the TT-TG distance sufficiently summarizes the pathoanatomy, and if this assists with planning of surgery in patellar instability. Cite this article: Bone Jt Open 2022;3(3):268-274.
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  • 文章类型: Journal Article
    诊断分类是提供最高质量和价值的护理的基础。诊断是模式识别,可以导致理想地指导治疗的疾病类别。虽然病理解剖诊断在骨科实践中是常见和传统的,他们在指导最佳物理治疗干预方面往往受到限制。已经提出了用非特异性区域疼痛标签替换病理解剖标签,并且在临床实践中经常发生。例如非特异性腰痛或不明原因的肩痛。这些标签避免了组织特异性病理解剖标签的一些缺点,但不足以指导治疗。提出了先前引入的运动系统诊断框架,并将其应用于肩部条件进行了更新。该框架具有在肌肉骨骼物理治疗师实践中广泛开发和应用的潜力。如果考虑到运动系统诊断分类,则可以提高和简化实践,同时认识到个体之间固有的运动变异性。
    Diagnostic classification is a foundational underpinning of providing care of the highest quality and value. Diagnosis is pattern recognition that can result in categories of conditions that ideally direct treatment. While pathoanatomic diagnoses are common and traditional in orthopaedic practice, they often are limited with regard to directing best practice physical therapy intervention. Replacement of pathoanatomic labels with non-specific regional pain labels has been proposed, and occurs frequently in clinical practice. For example non-specific low back pain or shoulder pain of unknown origin. These labels avoid some disadvantages of tissue specific pathoanatomic labels, but are not specific enough to direct treatment. A previously introduced movement system diagnostic framework is proposed and updated with application to shoulder conditions. This framework has potential for broad development and application across musculoskeletal physical therapist practice. Movement system diagnostic classification can advance and streamline practice if considered while recognizing the inherent movement variability across individuals.
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  • 文章类型: Journal Article
    BACKGROUND: Cervical spondylotic myelopathy (CSM) is the most common cause of spinal cord dysfunction. Magnetic resonance imaging (MRI) remains the imaging modality of choice, but its findings are not completely specific for clinically significant CSM. This cross-sectional study aims to determine the pathoanatomy of CSM in patients and analyze the correlations between clinical key symptoms, myelopathic signs, and MRI findings.
    METHODS: Patients with CSM aged 30 to 80 years old with no previous cervical spine disease or injuries were recruited. Clinical parameters include myelopathic hand signs and other clinical-specific tests. The MRI findings were analyzed for level of compression, underlying degenerative pathology, and parameters for cord compression.
    RESULTS: Thirty patients were recruited. The most common myelopathic signs observed were positive Hoffmann\'s sign and the presence of reverse brachioradialis reflex. All patients had either degenerative or prolapse disc changes on MRI. There was a positive correlation between the clinical key features with MRI parameters for canal and cord diameter. The transverse cord diameter, cord compression ratio, and approximate cord area were the only independent variables related to almost all the positive clinical specific tests. All three have a moderate to strong correlation with the clinical findings.
    CONCLUSIONS: The MRI parameters such as canal and cord size of the cervical spine are an objective reflection of compression on the spinal cord. Correlations observed indicate cord compression that plays a major role in the pathophysiology of CSM. These measurements are sensitive indicators of canal stenosis and play a significant role in predicting the severity and outcome of CSM.
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  • 文章类型: Journal Article
    OBJECTIVE: Vertebral body tethering (VBT) has been reported as a safe and effective non-fusion surgical technique for the treatment of adolescent idiopathic scoliosis, but the postoperative health of the bone and soft tissues of the spine following instrumentation remains unknown. We aimed to evaluate pathoanatomy and degenerative changes of the spine in adolescent idiopathic scoliosis patients both prior to and two years following VBT.
    METHODS: We prospectively enrolled nine patients who underwent VBT for the treatment of progressive adolescent idiopathic scoliosis. All patients received preoperative and two-year postoperative magnetic resonance imaging of their spine; images were assessed for pathoanatomy (e.g. nucleus pulposus positioning and muscle atrophy) and degenerative changes (e.g. Schmorl nodes, endplate oedema, disc degeneration, and osteoarthritis) at each vertebral level between T1 and S1.
    RESULTS: Four patients (44%) exhibited a shift of the nucleus pulposus from an eccentric position at baseline towards midline at three or more levels, most of which were in the tethered region. Tethering did not affect preexisting fatty atrophy of multifidus. No patients exhibited postoperative Schmorl nodes, endplate oedema, or disc degeneration in either the tethered or untethered regions. Four patients (44%) presented with mild facet osteoarthritis in the lower lumbar spine, which did not change postoperatively. One patient developed moderate facet osteoarthritis at L5-S1.
    CONCLUSIONS: These preliminary data indicate that VBT may not result in significant degenerative changes in either the intervertebral discs or the posterior facets two years following instrumentation.
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  • 文章类型: Journal Article
    Clubfoot is a common and complex, multi-segmental, 3-dimensional, congenital foot deformity. The segmental deformities have been recognized for millennia. They are cavus of the forefoot/midfoot, adductus of the midfoot, varus of the hindfoot, and equinus of the ankle, often referred to by the acronym CAVE. However, description of the deformities and their correction have varied over time with changes in consensus terminology for foot deformities and the understanding of foot biomechanics. In this narrative review, the most current terminology for foot deformities and understanding of foot biomechanics are applied to the clubfoot. The concept of the calcaneopedal unit (CPU) is applied to the in-depth discussion and understanding of clubfoot for perhaps the first time in the English language literature. Of the 4 basic clubfoot deformities, cavus and adductus are static structural deformities within the CPU, i.e., all bones of the foot except the talus. Varus is a restricted dynamic deformity between the CPU and the talus. Equinus is a restricted dynamic deformity in the ankle joint between the talus and the tibia. Understanding the CPU concept improves ones understanding of clubfoot deformities and the rationale for treatment techniques. Consensual agreement on the terms used to define interosseous relationships and motions in the foot improves communication. Finally, this narrative review highlights the histologic and biologic changes that occur in collagen and cartilage during clubfoot deformity correction to provide further understanding and rationale for treatment.
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  • 文章类型: Journal Article
    The research is aimed to introduce various corrective osteotomies utilized in treating calcaneal malunions in published papers, to further analyze the results, and to summarize recommended indications.
    The relevant research screening was conducted on the following search engines: the Cochrane Library, Web of Science, PubMed, Embase, Medline, and Academic Search Premier. Key words input included \"calcaneal/calcaneus\", \"malunion,\" and \"malunited fracture(s)\" with Boolean operators \"AND\" and \"OR.\" The inclusion criteria were researches containing surgical procedures treating calcaneal malunion with corrective osteotomy and published in the English language. For included research article, such information was extracted and analyzed: the type of calcaneal malunion, the time from initial injury to corrective surgery, the method of osteotomy, outcomes of each osteotomy (score systems, Bohler angle, talocalcaneal height and width of calcaneus, etc.), the function of the affected limb, post-operative complications, and patients\' satisfaction. For included review, descriptive, commentary, or indicative sentences about corrective osteotomy were highlighted, analyzed, and summarized.
    Ten research articles (170 patients with 184 feet) and nine reviews were included in this review, presenting seven types of corrective osteotomies (lateral wall exostectomy, Dwyer osteotomy, lateral wedge opening osteotomy, Romash osteotomy, tongue osteotomy, sagittal resection osteotomy, and modified Dwyer osteotomy).
    A different corrective osteotomy with/without arthrodesis is recommended to be utilized based on the classification of the malunion and the condition of the cartilage in treating malunited calcaneal fractures. With adequate postoperative care and rehabilitation, the results of treatment could be associated with patients\' satisfaction and good function.
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  • 文章类型: Journal Article
    简介:左心室过度扩张,也称为“非致密化”(LVHT)是一种心脏异常,可通过病理解剖检查或在心脏手术中检测到。成像技术通过心室造影显示LVHT,超声心动图,心脏磁共振成像(CMRI)和计算机断层扫描(CT)。涵盖的领域:我们旨在评估1)根据标准标准验证LVHT的定义的频率,2)如果评估了观察员之间和内部的协议,3)LVHT与遗传疾病的相关性。文献检索揭示了58例患者的心脏经过病理解剖学和≥1种成像技术的研究。与病理解剖学相比,超声心动图最常见(95%),其次是核磁共振成像(31%),心室造影(7%)和CT(5%)。与超声心动图定义相比,cMRI定义更频繁地评估观察者内部和观察者之间的一致性,并产生更一致的结果。由于仅从58例病例中的4例报告了遗传发现,与影像学检查结果无关联.专家意见:病理解剖研究与成像技术之间的相关性有望有助于LVHT的可靠和统一接受的定义。很可能,LVHT的超声心动图定义将是当前使用的定义的综合,集成短轴和四腔视图。cMRI定义的改进,考虑病理解剖和超声心动图检查,似乎有必要避免过度诊断。
    Introduction: Left ventricular hypertrabeculation, also named \'noncompaction\' (LVHT) is a cardiac abnormality which is detected by pathoanatomic investigation or during cardiac surgery. Imaging techniques visualize LVHT by ventriculography, echocardiography, cardiac magnetic resonance imaging (CMRI) and computed tomography (CT).Areas covered: We aimed to assess 1) how often the definition of LVHT was validated against a criterion standard, 2) if inter- and intra-observer agreement was assessed, and 3) how often LVHT was associated with genetic diseases. A literature search disclosed 58 cases whose hearts were investigated pathoanatomically and by ≥1 imaging technique. Echocardiography was most frequently (95%) compared with pathoanatomy, followed by cMRI (31%), ventriculography (7%) and CT (5%). Intra- and inter-observer agreement was more frequently assessed for cMRI definitions and yielded more consistent results than for echocardiographic definitions. Since genetic findings were only reported from 4 of the 58 cases, no association with imaging findings could be carried out.Expert opinion: Correlation between pathoanatomic investigations with imaging techniques will hopefully contribute to reliable and uniformly accepted definitions of LVHT. Most probably, the echocardiographic definition of LVHT will be a synthesis of the currently used definitions, integrating short axis and four-chamber views. A refinement of cMRI definitions, considering pathoanatomic and echocardiographic investigations, seems necessary to avoid overdiagnosis.
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