Parálisis de Bell

贝尔帕拉斯
  • 文章类型: Journal Article
    目的:评估COVID-19疫苗接种后贝尔麻痹的合并发病率。
    方法:PubMed,Scopus,EMBASE,WebofScience,谷歌学者被两名独立研究人员搜索。我们还搜索了灰色文献,包括参考文献和会议摘要的参考文献。我们提取了有关参与者总数的数据,第一作者,出版年份,原产国,女/男,疫苗的类型,以及接种COVID-19疫苗后出现贝尔麻痹的患者人数。
    结果:文献检索显示370篇文章,随后删除重复227剩余。在仔细评估全文后,仍有20篇文章进行荟萃分析。最常用的疫苗是辉瑞,其次是Moderna。总的来说,4.54e+07人接种了COVID-19疫苗,1739例出现贝尔麻痹。在九项研究中,纳入对照组(未接种疫苗的个体).总人数为9018069人,其中,203发展为贝尔麻痹。COVID-19疫苗接种后贝尔麻痹的发生率可忽略不计。COVID-19疫苗接种后发生贝尔麻痹的几率为1.02(95CI:0.79-1.32)(I2=74.8%,p<0.001)。
    结论:这项系统评价和荟萃分析的结果表明,接种COVID-19疫苗后周围性面神经麻痹的发生率是可以忽略的,接种疫苗不会增加发生贝尔氏麻痹的风险。也许,贝尔氏麻痹是一种更严重形式的COVID-19的表现症状,因此临床医生必须意识到这一点。
    OBJECTIVE: To estimate the pooled incidence of Bell\'s palsy after COVID-19 vaccination.
    METHODS: PubMed, Scopus, EMBASE, Web of Science, and Google Scholar were searched by 2 independent researchers. We also searched the grey literature including references of the references and conference abstracts. We extracted data regarding the total number of participants, first author, publication year, the country of origin, sex, type of vaccines, and the number of patients who developed Bell\'s palsy after COVID-19 vaccination.
    RESULTS: The literature search revealed 370 articles, subsequently deleting duplicates 227 remained. After careful evaluation of the full texts, 20 articles remained for meta-analysis. The most commonly administered vaccines were Pfizer followed by Moderna. In total, 4.54e+07 individuals received vaccines against COVID-19, and 1739 cases developed Bell\'s palsy. In nine studies, controls (individuals without vaccination) were enrolled. The total number of controls was 1 809 069, of whom 203 developed Bell\'s palsy. The incidence of Bell\'s palsy after COVID-19 vaccines was ignorable. The odds of developing Bell\'s palsy after COVID-19 vaccines was 1.02 (95% CI: 0.79-1.32) (I2 = 74.8%, P < .001).
    CONCLUSIONS: The results of this systematic review and meta-analysis show that the incidence of peripheral facial palsy after COVID-19 vaccination is ignorable and vaccination does not increase the risk of developing Bell\'s palsy. Maybe, Bell\'s palsy is a presenting symptom of a more severe form of COVID-19, so clinicians must be aware of this.
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  • 文章类型: Observational Study
    目的:了解三级医院周围性面神经麻痹(PFP)患者的临床和流行病学特征。
    方法:这是一项在三级医疗中心接受治疗的PFP患者的回顾性观察性研究。我们收集了人口统计数据,病因学,偏侧性,复发,recovery,临床眼科,根据House-Brackmann(HB)量表,电生理测试,参加医疗服务,医学和外科治疗。
    结果:包括二百八十三个PFP,男性135人(48%),女性148人(52%)(p=0.47)。所有患者均有单侧受累。平均年龄为54±20岁。215例(76%)患者的主要病因是特发性。中位恢复时间为7周。190例(67%)患者完全恢复。一百七十(84%)特发性PFP患者完全恢复,非特发性PFP患者30例(16%)(p<0.01)。84%的患者为HBⅡ级,完全恢复,而HBVI级仅恢复了17%(p=0.003)。二百二十九名患者(81%)患有痛觉。大部分接受眼表护理治疗的有271例(96%)患者,其中249例(88%)患者接受口服皮质类固醇治疗。13例患者(5%)需要眼科手术。
    结论:PFP影响所有年龄范围,不偏爱性和单方面。其主要原因是特发性。在大多数情况下,恢复已完成,对轻度和特发性情感更有利。大多数只需要医疗。
    OBJECTIVE: To identify clinical and epidemiological characteristics of patients with peripheral facial palsy (PFP) at a tertiary care hospital.
    METHODS: This is a retrospective observational study of patients with PFP treated at a tertiary medical center. We gathered demographic data, etiology, laterality, recurrence, recovery, clinical ophthalmology, severity according to the House-Brackmann (HB) scale, electrophysiological tests, medical services attended, medical and surgical treatment.
    RESULTS: Two hundred and eighty-three PFP were included, 135 (48%) were men and 148 (52%) were women p = 0.47). All patients had unilateral involvement. The mean age was 54 ± 20 years. The main etiology was idiopathic in 215 (76%) patients. Median recovery time was 7 weeks. Recovery was complete in 190 (67%) patients. One hundred and seventy (84%) patients with idiopathic PFP had complete recovery, versus 30 (16%) patients with non-idiopathic PFP (p < 0.01). The 84% of patients with HB grade II, recovered completely, while with HB grade VI only 17% recovered (p = 0.003). Two hundred and twenty-nine patients (81%) had lagophthalmos. The majority received ocular surface care treatment in 271 (96%) patients and of these 249 (88%) patients received oral corticosteroid therapy. Thirteen patients (5%) required ophthalmologic surgery.
    CONCLUSIONS: PFP affects all age ranges, without predilection for sex and unilateral. Its main cause is idiopathic. Recovery is complete in most cases, being more favorable in mild and idiopathic affections. Most only require medical treatment.
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  • 文章类型: Practice Guideline
    贝尔氏麻痹是与面神经无力或麻痹相关的最常见诊断。然而,并非所有面部麻痹/瘫痪患者都有贝尔氏麻痹。其他常见原因包括前庭神经鞘瘤的治疗,头颈部肿瘤,医源性损伤,带状疱疹,或者外伤.对这些条件中的每一个的方法差别很大。本指南的目的是为临床医生提供治疗和监测不同原因的面瘫患者的指导。我们打算起草一项切实可行的指导方针,重点关注被认为对患者日常管理有用的操作性建议。该指南由西班牙耳鼻喉科学会推广,并由一群对面神经疾病感兴趣的医生开发。包括来自每个自治区的至少一名医生。以问答的形式,它包括56个与面神经有关的相关主题。
    Bell\'s palsy is the most common diagnosis associated with facial nerve weakness or paralysis. However, not all patients with facial paresis/paralysis have Bell\'s palsy. Other common causes include treatment of vestibular schwannoma, head and neck tumours, iatrogenic injuries, Herpes zoster, or trauma. The approach to each of these conditions varies widely. The purpose of this guideline is to provide clinicians with guidance on the treatment and monitoring of patients with different causes of facial paralysis. We intend to draft a practical guideline, focusing on operationalised recommendations deemed to be useful in the daily management of patients. This guideline was promoted by the Spanish Society of Otolaryngology and developed by a group of physicians with an interest in facial nerve disorders, including at least one physician from each Autonomous Community. In a question and answer format, it includes 56 relevant topics related to the facial nerve.
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