据报道棕榈油酸(ω-7)主要对代谢紊乱有效。最近,据报道,它可以通过改善皮肤症状来帮助改善生活质量(QoL)。
■这项随机研究的目的是,双盲,安慰剂对照临床研究旨在评价口服棕榈油酸改善皮肤屏障的有效性和安全性,弹性,和成年女性的皱纹形成。
■在这个随机的,双盲,安慰剂对照临床研究,纳入90名健康参与者,接受500毫克/天的棕榈油酸(干预)或不含棕榈油酸的玉米油(对照),持续12周。皮肤水合和经表皮水分流失和皮肤弹性,表面粗糙度,眼睛皱纹体积,每隔6周测量一次皱纹严重程度,以评估皮肤屏障功能和改善皱纹的功效,分别。
■12周后,与对照组相比,干预组的皮肤水合作用和经表皮水分流失显着改善。皮肤弹性,表面粗糙度,眼睛皱纹体积,皱纹严重程度,参与者评估的临床改善评分与对照组相比没有显著改善.
■口服棕榈油酸有效改善皮肤屏障功能,这可能会提高老年人的QoL。
UNASSIGNED: Palmitoleic acid (omega-7) has been reported to be effective primarily for metabolic disorders. Recently, it has been reported to help improve quality of life (QoL) by improving skin symptoms.
UNASSIGNED: The aim of this randomized, double-blinded, placebo-controlled clinical study is to evaluate the efficacy and safety of oral palmitoleic acid in improving skin barrier, elasticity, and wrinkle formation in adult women.
UNASSIGNED: In this randomized, double-blind, placebo-controlled clinical study, 90 healthy participants were enrolled and received 500 mg/day palmitoleic acid (intervention) or corn oil without palmitoleic acid (control) for 12 weeks. Skin hydration and transepidermal water loss and skin elasticity, surface roughness, eye wrinkle volume, and wrinkle severity were measured at 6-week intervals to assess the skin barrier function and efficacy in wrinkle improvement, respectively.
UNASSIGNED: After 12 weeks, skin hydration and transepidermal water loss significantly improved in the intervention group compared to the control group. Skin elasticity, surface roughness, eye wrinkle volume, wrinkle severity, and participant-assessed clinical improvement score did not significantly improve compared with the control group.
UNASSIGNED: Oral palmitoleic acid effectively improves the skin barrier function improvement, which may enhance QoL in aging adults.