Pacemaker

起搏器
  • 文章类型: Case Reports
    BACKGROUND: This case report highlights the novel role of His-bundle pacing (HBP) from right atrium, not just for preserving cardiac function, but also for avoiding interference with TriClip devices.
    RESULTS: A 78-year-old female with severe tricuspid regurgitation received two TriClip devices. Postprocedure, frequent significant sinus pauses required a pacemaker. HBP was chosen to avoid lead complications. Under local anesthesia, a His pacing lead was inserted via the axillary vein using specialized catheter. Follow-ups over 2.5 years showed stable parameters with no complications.
    CONCLUSIONS: HBP is effective for patients with TriClip devices, ensuring optimal cardiac function and lead stability.
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  • 文章类型: Journal Article
    背景:提供了2023年西班牙心脏起搏系统植入物的数据。
    方法:注册表基于中心在植入设备后向心律协会的记录平台提供的信息,通过心血管疾病,国家注册局的在线平台。其他信息来源包括:a)来自制造和销售行业的数据传输;b)欧洲起搏器患者卡;和c)植入中心提交的本地数据库。
    结果:2023年,有112家医院参加了注册(比2022年增加了30家)。总共报告了24343例设备植入(比2022年增加48.1%),而Eucomed(欧洲医疗供应商协会联合会)报告了45120例。其中,1646个是心脏再同步化治疗起搏器。增幅最大的设备是无引线起搏器,植入了963个装置,比2022年增长18.1%。最常见的指征是随后的房室传导阻滞,第一次,房性快速性心律失常伴缓慢的心室反应。远程监测中包括的设备数量也增加了(心脏再同步治疗除颤器,71%;心脏再同步治疗起搏器,63%;和常规起搏器,28%),虽然更温和。
    结论:在2023年,参与注册的机构数量有所增加。植入器械的报告上升了48.1%,无引线起搏器的植入量增长了18.1%。与前几年相比,远程监控也略有增长。英文全文可查阅:www.revespcardiol.org/en。
    BACKGROUND: Data on implants of cardiac pacing systems in Spain in 2023 are presented.
    METHODS: The registry is based on the information provided by centers to the recording platform of the Heart Rhythm Association after device implantations, through Cardiodispositivos, the online platform of the National Registry. Other information sources include: a) data transfers from the manufacturing and marketing industry; b) the European pacemaker patient card; and c) local databases submitted by the implanting centers.
    RESULTS: In 2023, 112 hospitals participated in the registry (30 more than in 2022). A total of 24 343 device implantations were reported (48.1% more than in 2022) compared with 45 120 reported by Eucomed (European Confederation of Medical Suppliers Associations). Of these, 1646 were cardiac resynchronization therapy pacemakers. The devices showing the largest increases were leadless pacemakers, with 963 devices implanted, representing an 18.1% increase over 2022. The most frequent indication was atrioventricular block followed, for the first time, by atrial tachyarrhythmia with slow ventricular response. The number of devices included in remote monitoring also increased (cardiac resynchronization therapy defibrillators, 71%; cardiac resynchronization therapy pacemakers, 63%; and conventional pacemakers, 28%), although more moderately.
    CONCLUSIONS: In 2023, there was an increase in the number of institutions participating in the registry. The reporting of device implantations rose by 48.1%, and the implantation of leadless pacemakers grew by 18.1%. Remote monitoring also experienced modest growth compared with previous years. Full English text available from: www.revespcardiol.org/en.
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  • 文章类型: Journal Article
    背景:房室传导阻滞(AVB)在老年人中很常见,因此被认为是心脏传导系统的退行性疾病。然而,在年轻患者中还存在导致AVB的其他病因.本研究旨在确定60岁之前在中国首次植入AVB起搏器的患者的病因。
    结果:在2010年至2021年期间,在广东省人民医院对AVB患者的病历和诊断测试进行了回顾,以确定病因。包括8126名患者(中位年龄47岁;47.9%的男性)。在336例(40.7%)病例中发现了病因,包括心脏手术并发症(n=190[23.0%]),心肌炎(n=57[6.9%]),心肌梗死(n=25[3.0%]),基于导管的介入手术并发症(n=21[2.5%])和其他并发症(n=43[5.2%])。由心肌梗死引起的AVB在男性中更为常见(5.8%vs.0.5%,p<.001),而女性较早接受起搏治疗(48vs.46年,p=.019)。男性更容易患扩张型心肌病(6.6%vs.2.1%,p=.001)和心房颤动/扑动(23.0%vs.12.8%,p<.001)。首次植入起搏器的数量随着年龄的增长而增加,尤其是在病因不明的患者中。
    结论:AVB的病因仅在大约40%的60岁之前接受首次起搏器植入的患者中确定。AVB的主要病因未知和潜在的性别差异值得进一步研究。
    BACKGROUND: Atrioventricular block (AVB) is common in the elderly and therefore considered to be a degenerative disease of the cardiac conduction system. However, there exist other etiologies contributing to AVB in young patients. This study aimed to determine the etiologies in patients aged before 60 years receiving their first pacemaker implantation for AVB in China.
    RESULTS: Medical records and diagnostic tests of AVB patients were reviewed to identify the etiologies between 2010 and 2021 at Guangdong Provincial People\'s Hospital. Eight hundred and twenty-six patients (median age 47 years; 47.9% males) were included. The etiologies were identified in 336 (40.7%) cases, including complications to cardiac surgery (n = 190 [23.0%]), myocarditis (n = 57 [6.9%]), myocardial infarction (n = 25 [3.0%]), complications to catheter-based interventional procedures (n = 21 [2.5%]) and others (n = 43 [5.2%]). AVB caused by myocardial infarction was more common in men (5.8% vs. 0.5%, p < .001), while women received pacing treatment earlier (48 vs. 46 years, p = .019). Men were more likely to suffer from dilated cardiomyopathy (6.6% vs. 2.1%, p = .001) and atrial fibrillation/flutter (23.0% vs. 12.8%, p < .001). The number of first pacemaker implantation increased with age especially among patients with unclear etiologies.
    CONCLUSIONS: The etiology of AVB was only determined in approximately 40% of patients receiving their first pacemaker implantation aged before 60 years. The predominance of AVB with unknown etiology and potential gender differences warrants further studies.
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  • 文章类型: Journal Article
    在过去的二十年中,心脏起搏器技术的前景经历了重大的发展,从简单的单腔设备过渡到复杂的多腔速率响应系统和心律转复除颤器。这一进展引入了一系列复杂的设备植入和手术固有的并发症,包括机械和临床挑战。这些并发症尤其包括导线移位,设备迁移,静脉血栓形成,还有血胸,这不仅会影响患者的治疗结果,还会带来巨大的经济负担。这篇综述仔细分析了这些并发症,阐明它们的机制,临床意义,以及与其管理相关的经济后果。它还概述了旨在减轻这些并发症的当前和新兴战略,强调需要不断更新的临床实践和协议。通过这个话语,该审查旨在使临床医生对这些并发症有全面的了解,从而提高心脏起搏干预的安全性和有效性。
    The landscape of cardiac pacemaker technology has undergone significant evolution over the last two decades, transitioning from simple single-chamber devices to sophisticated multi-chamber rate-responsive systems and cardioverter defibrillators. This progression has introduced a complex array of complications inherent to device implantation and operation, encompassing both mechanical and clinical challenges. These complications notably include lead dislodgment, device migration, venous thrombosis, and hemothorax, which not only affect patient outcomes but also impose substantial economic burdens. This review meticulously analyzes these complications, elucidating their mechanisms, clinical implications, and the economic consequences associated with their management. It also outlines current and emerging strategies aimed at mitigating these complications, emphasizing the need for continual updates in clinical practices and protocols. Through this discourse, the review seeks to equip clinicians with a comprehensive understanding of these complications, thereby enhancing the safety and efficacy of cardiac pacing interventions.
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  • 文章类型: Systematic Review
    这篇综述介绍了用于各种生物医学目的的可植入天线的深入研究。植入式天线的发展,包括他们的设计,材料,和操作原理,是在讨论开始时介绍的。本研究概述了植入式医疗设备(IMD)中使用的多种植入式天线。然后,本文讨论了开发用于生物医学目的的可植入天线时要考虑的重要因素,包括植入物放置,频率范围,和电力需求。本调查还检查了植入式天线遇到的挑战和局限性。包括人体内有限的可用空间,对生物相容性材料的要求,周围组织对天线性能的影响,组织衰减,和信号干扰。这篇综述还强调了植入式天线技术的最新进展,如无线电力传输,多频带操作,和小型化。此外,它提供了植入式天线的几种生物医学用途的插图,包括起搏器,胶囊内窥镜检查,颅内压监测,视网膜假体,和骨植入物。本文最后讨论了植入式天线的未来及其在生物电子医学和新型医疗植入物中的可能用途。总的来说,这项调查对生物医学应用中的植入式天线进行了全面分析,强调它们在植入式医疗技术发展中的重要性。
    This review presents an in-depth examination of implantable antennas for various biomedical purposes. The development of implantable antennas, including their designs, materials, and operating principles, are introduced at the beginning of the discussion. An overview of the many kinds of implantable antennas utilized in implantable medical devices (IMDs) are presented in this study. The article then discusses the important factors to consider when developing implantable antennas for biomedical purposes, including implant placement, frequency range, and power needs. This investigation additionally examines the challenges and limitations encountered with implantable antennas, including the limited space available within the human body, the requirement for biocompatible materials, the impact of surrounding tissue on antenna performance, tissue attenuation, and signal interference. This review also emphasizes the most recent advances in implanted antenna technology, such as wireless power transmission, multiband operation, and miniaturization. Furthermore, it offers illustrations of several biomedical uses for implantable antennas, including pacemaker, capsule endoscopy, intracranial pressure monitoring, retinal prostheses, and bone implants. This paper concludes with a discussion of the future of implantable antennas and their possible use in bioelectronic medicine and novel medical implants. Overall, this survey offers a thorough analysis of implantable antennas in biomedical applications, emphasizing their importance in the development of implantable medical technology.
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  • 文章类型: Journal Article
    背景:传导障碍对经导管主动脉瓣置换术(TAVR)后的长期左心室射血分数(LVEF)具有不确定性。我们旨在检查TAVR后两年内患者的LVEF变化。
    方法:我们检查了2012年至2020年接受TAVR的患者,并进行了超声心动图随访。患者分为四组:1)TAVR前后无永久性起搏器(PPM)或左束支传导阻滞(LBBB)的患者;2)TAVR前后LBBB的患者;3)先前存在PPM的患者;4)TAVR后需要新PPM的患者。LVEF在TAVR开始时进行了评估,在30天,1年,和2年后TAVR。
    结果:该研究包括730例患者:421例(57.6%)无传导异常,151(20.7%)具有TAVR后LBBB(48个预先存在,103新发),63(8.6%),具有预先存在的PPM,95(13.1%)需要新的PPM。出院时,没有传导异常的患者表现出最高的LVEF(57.4±11.5%),而那些预先存在PPM的人最低(48.1±15.5%).两年多了,在没有传导问题的患者和具有预先存在的PPM的患者中,LVEF保持恒定。然而,新的LBBB患者的LVEF下降了6.3%,和那些需要新的PPM显示减少4.1%。
    结论:新的传导异常,例如LBBB或PPM的需要,诱导LVEF下降后TAVR。必须将重点放在TAVR后经历新的传导障碍的患者的左心室功能的长期监测上。
    BACKGROUND: Conduction disturbances have uncertain implications for long-term left ventricular ejection fraction (LVEF) after transcatheter aortic valve replacement (TAVR). We aimed to examine LVEF changes in patients up to two years post-TAVR.
    METHODS: We examined patients who underwent TAVR between 2012 and 2020 and underwent echocardiography follow-up. Patients were categorized into four groups: 1) Those without a permanent pacemaker (PPM) or left bundle branch block (LBBB) pre- or post-TAVR; 2) Patients with pre- and post-TAVR LBBB; 3) Individuals with preexisting PPM; and 4) Patients requiring new PPM after TAVR. LVEF was assessed at the outset of TAVR, at 30 days, 1-year, and 2-years post-TAVR.
    RESULTS: The study included 730 patients: 421 (57.6 %) without conduction abnormalities, 151 (20.7 %) with post-TAVR LBBB (48 pre-existing, 103 new-onset), 63 (8.6 %) with pre-existing PPM, and 95 (13.1 %) requiring new PPM. At discharge, patients without conduction abnormalities exhibited the highest LVEF (57.4 ± 11.5 %), whereas those with pre-existing PPM had the lowest (48.1 ± 15.5 %). Over two years, LVEF remained constant in patients without conduction issues and in those with pre-existing PPM. However, patients with new LBBB experienced a 6.3 % decrease in LVEF, and those requiring new PPM showed a 4.1 % reduction.
    CONCLUSIONS: New conduction abnormalities, such as LBBB or the need for PPM, induce a decline in LVEF post-TAVR. It is imperative to focus on the long-term monitoring of left ventricular function in patients experiencing new conduction disturbances post-TAVR.
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  • 文章类型: English Abstract
    The 2018 guidelines of the European Society of Cardiology (ESC) provide improved algorithms for the diagnostics and treatment of syncope. New guidelines on ventricular tachycardia, on the prevention of sudden cardiac death and on cardiomyopathies and pacemakers have refined the recommendations. The detailed medical history and examination are crucial for differentiating between cardiac and noncardiac causes and determining the appropriate treatment. High-risk patients need urgent and comprehensive diagnostics. The basic diagnostics include medical history, physical examination and a 12-lead electrocardiography (ECG). Further tests, such as long-term ECG monitoring, implantable loop recorders and electrophysiological investigations are helpful in unclear cases. The treatment depends on the cause, with pacemaker implantation and implantable cardioverter defibrillators (ICD) being important for cardiac causes, while behavioral measures and medication management have priority for noncardiac syncope.
    UNASSIGNED: Die 2018 veröffentlichten Leitlinien der European Society of Cardiology (ESC) bieten verbesserte Algorithmen für die Diagnostik und die Behandlung von Synkopen. Neue Leitlinien zu ventrikulären Tachykardien, zur Prävention des plötzlichen Herztodes sowie zu Kardiomyopathien und Schrittmachertherapie haben die Empfehlungen verfeinert. Die genaue Anamnese und Untersuchung sind entscheidend für die Differenzierung zwischen kardialen und nichtkardialen Ursachen sowie für die Festlegung der Therapie. Bei hohem Risiko ist eine rasche und umfassende Diagnostik notwendig. Die Basisdiagnostik umfasst Anamnese, körperliche Untersuchung und 12-Kanal-EKG(Elektrokardiographie). Weitere Tests wie Langzeit-EKG, implantierbare Ereignisrekorder und elektrophysiologische Untersuchungen sind bei unklaren Fällen hilfreich. Die Therapie richtet sich nach der Ursache, wobei Schrittmacherimplantationen und implantierbare Kardioverter-Defibrillatoren (ICD) bei kardialen Ursachen wichtig sind, während bei nichtkardialen Synkopen Verhaltensmaßnahmen und Medikamentenmanagement im Vordergrund stehen.
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  • 文章类型: Journal Article
    大部分接受经导管三尖瓣介入治疗(TTVI)的患者将存在心脏可植入电子设备(CIED)。在这样的病人中,手术矫正三尖瓣返流(TR)与高发病率和高死亡率相关.经静脉引线提取(TLE)可能会改善CIED引起的TR;但是,它具有固有的风险,通常不会导致TR改善。随着多个TTVI设备正在试用以获得监管部门的批准,了解哪种治疗在aCIED患者中最合适是至关重要的.这篇综述集中在非手术治疗,包括TLE和经导管三尖瓣修复和置换选项,旨在提高同时患有CIED的TR患者的预后。
    A large proportion of patients referred for transcatheter tricuspid valve intervention (TTVI) will have the presence of a cardiac implantable electronic device (CIED). In such patients, surgical correction of tricuspid regurgitation (TR) is associated with high rates of morbidity and mortality. Transvenous lead extraction (TLE) could potentially ameliorate CIED-induced TR; however, it carries inherent risks and frequently does not result in TR improvement. As multiple TTVI devices are in trial to gain regulatory approval, understanding which therapy is most appropriate among patients with a CIED is essential. This review centers on the nonsurgical treatment, including TLE and transcatheter tricuspid valve repair and replacement options, aimed at enhancing outcomes in patients with TR who also have concurrent CIEDs.
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  • 文章类型: Case Reports
    背景:现代心血管可植入电子设备(CIED)具有防止外部电击损害的机制,意外触电后的故障很少见。然而,闪电损伤对CIED患者的影响尚不确定。
    方法:一名74岁男子因完全心脏传导阻滞而使用双腔起搏器,在耕作时被闪电击中。他当时没有严重受伤,一个月后寻求医疗评估,当他出现无症状的心动过缓时。设备询问提示重大电池和导线损坏,需要提取并随后放置新的起搏系统。
    结论:虽然以前的报告描述了起搏阈值升高而没有广泛的设备损伤,我们的患者出现了对整个起搏系统的重大损害。导致这些不同结果的因素尚不清楚。损伤机制的差异,起搏器型号,并且装置内的电流分散模式可以各自在这种差异中起作用。
    BACKGROUND: Modern cardiovascular implantable electronic devices (CIEDs) have mechanisms that prevent damage from external electric shocks, and malfunction following accidental electrocution is rare. However, the effects of lightning injuries in patients with CIEDs are uncertain.
    METHODS: A 74-year-old man with a dual-chamber pacemaker due to complete heart block was struck by a lightning while farming. He had no serious injury at the time and sought medical evaluation 1 month later, when he presented with asymptomatic bradycardia. Device interrogation suggested major battery and lead damage, requiring extraction and subsequent placement of a new pacing system.
    CONCLUSIONS: While a previous report depicted pacing threshold elevation without extensive device impairment, our patient presented with major damage to the whole pacing system. The factors contributing to these divergent outcomes are unclear. Differences in injury mechanism, pacemaker model, and the pattern of electric current dispersion within the device may each play a part in this discrepancy.
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  • 文章类型: Journal Article
    背景:MICRA植入通常不作为日常手术进行。我们中心常规植入选择性无导线起搏器。
    目的:评估日间MICRA手术是否安全。
    方法:我们回顾性收集了2014年5月至2022年11月在我们中心进行MICRA选择性植入的所有患者的数据(n=81)。两组患者进行了分层:计划在同一天出院的患者(SD,n=52)和计划在手术后过夜观察的那些(ON,n=29)。患者人口统计学,使用的护套的尺寸,MICRA设备的类型,并记录并发症发生率。在成功植入的患者中(n=80),评估了出院时的设备功能和首次常规随访。
    结果:SD组男性占58%,ON组男性占45%。SD的中位年龄为49岁,ON的中位年龄为67岁。在计划作为日间病例的患者中,8例患者不得不留在医院,但<48小时:2由于轻微的腹股沟出血,1由于患者的要求,尽管适合出院,4由于当天晚些时候进行的程序,由于程序的复杂性,1用于观察。80例患者MICRA植入成功。SD组的主要并发症发生率为2%,ON组为7%(p=0.223),评估的合并症均未显示与任何并发症相关.76名患者在随访时获得了设备参数。随访时PCT低且稳定的患者率在SD组中也为98%,在ON组中为96%。
    结论:在适当选择的患者群体中,可以安全地进行日间病例MICRA手术。
    BACKGROUND: MICRA implantation is not commonly done as a day-case procedure. Elective leadless pacemakers are implanted routinely in our centre.
    OBJECTIVE: To assess whether the day-case MICRA procedure is safe.
    METHODS: We retrospectively collected data from all patients undergoing elective MICRA implantation at our centre between May 2014 and Nov 2022 (n = 81). Two patient groups were stratified: those planned to be discharged on the same day (SD, n = 52) and those planned to be observed overnight after the procedure (ON, n = 29). Patient demographics, size of the sheath used, type of MICRA device, and rate of complications were recorded. In patients with successful implants (n = 80), device function at discharge and first routine follow-up were evaluated.
    RESULTS: There were 58% males in the SD group and 45% in the ON group. Median age was 49 years in the SD and 67 years in the ON. Among patients who were planned as a day case, 8 patients had to stay in the hospital but for < 48 h: 2 due to minor groin bleeding, 1 due to patient\'s request despite fit to discharge, 4 due to the procedure carried out later in the day, and 1 for observation due to procedural complexity. MICRA implantation was successful in 80 patients. The rate of the major complications was 2% in the SD group and 7% in the ON group (p = 0.223), and none of the co-morbidities assessed showed an association with any complications. Device parameters at the follow-up were available in 76 patients. The rate of patients with low and stable PCT at follow-up was also 98% in the SD group and 96% in the ON group.
    CONCLUSIONS: Day case MICRA procedure can be performed safely in an appropriately selected patient population.
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