背景:抗阻运动诱导血小板增多并增加血小板活化和功能。这些变化可能与运动变量有关,包括运动强度和类型。
目的:我们比较了传统抗阻运动(TRE)和回路抗阻运动(CRE)对血小板活化和功能的细胞标志物的影响。
方法:在这项交叉研究中,有10名健康男性(平均值±SD:年龄,25.6±2.4年)进行TRE的受试者在10-RM的100%(最多10次重复)的情况下进行了3组10次重复,进行了6次练习,CRE协议包括3组10次重复,10-RM的100%连续进行6次练习,在两个单独的星期。为了测量血小板指数,PAC1,CD41a,CD42b和CD62P三个血样前,锻炼后立即,30分钟后恢复。
结果:乳酸浓度,血压,血小板计数(PLT),在两项抗阻运动试验后,平均血小板体积(MPV)均显着(p<0.05)增加。在两个RE之后检测到PAC1和CD62P的显著增加;以及CD42b和CD41a的显著降低(p<0.05)。然而,PAC1和CD62P的变化在两种方案之间存在显着差异(p<0.05),CRE后检测到更高的增加。
结论:急性RE增加血小板指数和血小板活化;CRE导致比TRE更高的血小板活化,可能是由于运动引起的剪切应力增加。
BACKGROUND: Resistance exercise induces thrombocytosis and increases platelet activation and function. These changes might be related to exercise variables including exercise intensity and type.
OBJECTIVE: We compared the effects of traditional resistance exercise (TRE) and circuit resistance exercise (CRE) on cellular markers of platelet activation and function.
METHODS: In this crossover study ten healthy male (mean±SD: age, 25.6±2.4 years) subjects performed TRE encompassed 3 sets of 10 repetitions at 100% of 10-RM (10 repetition maximum) for 6 exercises, and CRE protocols included 3 sets of 10 repetitions at 100% of 10-RM for all 6 exercises consecutively, in two separate weeks. To measure platelet indices,
PAC1, CD41a, CD42b and CD62P three blood samples were taken before, immediately after exercise, and after 30 min recovery.
RESULTS: Lactate concentration, blood pressure, platelet count (PLT), and mean platelet volume (MPV) were significantly (p < 0.05) increased following both resistance exercise trials. Significant increases in
PAC1, and CD62P; and significant reductions for CD42b and CD41a were detected following both REs (p < 0.05). However, changes in
PAC1 and CD62P were significantly different between the two protocols (p < 0.05), with higher increases detected following CRE.
CONCLUSIONS: Acute RE increases platelet indices and platelet activation; and that CRE results in higher platelet activation than TRE, probably due to exercise-induced increases in shear stress.