抗球虫耐药性的发展和对药物残留的担忧促使人们对对抗疗法药物的替代品进行评估。在目前的研究中,与姜黄和生姜的抗球虫作用进行了比较。90只绵羊,自然感染艾美球虫。随机选择最低卵囊/克(OPG)计数高于5000的粪便,并分成6组,每组15只动物。动物补充了62.50mg/kg体重(bw)(GI)姜黄@200和300毫克/千克体重(GII和GIII)和生姜@200和300毫克/千克体重(GIV和GV),口服7天,GVI动物作为未处理的感染对照。在治疗前第0天和第8天收集粪便样本,14日,开始治疗后第21天和第28天,并使用粪便卵囊计数减少试验(FOCRT)进行评估。氨丙利的有效率为93.18%,96.82%,8日的95.56%和95.80%,14日,第21天和第28天,开始治疗后。姜黄@200mg/kgb.w.显示41.49%的功效,52.37%,61.47%和60.08%,姜黄@300毫克/千克体重为44.92%,54.32%,8th有效64.21%和61.95%,14日,第21天和第28天,分别。生姜@200mg/kgbw显示38.51%的功效,53.48%,55.38%和55.53%,生姜@300毫克/千克体重为39.65%,54.81%,8th有效57.18%和58.22%,14日,第21天和第28天,分别。结果证明了在临床球虫病中使用氨纶,而姜黄和生姜可用作天然的预防性替代品。
Development of anticoccidial resistance and concerns of drug residues have prompted the evaluation of alternatives to allopathic drugs. In current study, anticoccidial effect of amprolium was compared with that of Curcuma longa and Zingiber officinale. Ninety (90) sheep, naturally infected with Eimeria spp. and having a minimum oocyst per gram (OPG) count of faeces above 5000 were randomly selected and divided into six groups of 15 animals each. Animals were supplemented with amprolium @ 62.50 mg/kg body weight (bw) (GI), turmeric @ 200 and 300 mg/kg bw (GII and GIII) and ginger @ 200 and 300 mg/kg bw (GIV and GV), orally for 7 days and GVI animals were kept as untreated infected control. Faecal samples were collected on \'0\' day before treatment and on 8th, 14th, 21st and 28th day after starting treatment and evaluated using Faecal oocyst count reduction test (FOCRT). The efficacy of amprolium was 93.18%, 96.82%, 95.56% and 95.80% on 8th, 14th, 21st and 28th day, after starting treatment. Turmeric @200 mg/kg b.w. showed efficacy of 41.49%, 52.37%, 61.47% and 60.08% and turmeric @ 300 mg/kg bw was 44.92%, 54.32%, 64.21% and 61.95% effective on 8th, 14th, 21st and 28th day, respectively. Ginger @200 mg/kg bw showed efficacy of 38.51%, 53.48%, 55.38% and 55.53% and ginger @ 300 mg/kg bw was 39.65%, 54.81%, 57.18% and 58.22% effective on 8th,14th, 21st and 28th day, respectively. The results justify use of amprolium for clinical coccidiosis while Curcuma longa and Gingiber officinale could be used as natural prophylactic alternatives.