Osteoid osteoma

骨样骨瘤
  • 文章类型: Case Reports
    骨样骨瘤(OO)是一种常见的良性骨化性病变,在年轻人中最为普遍。通常,它攻击管状的骨干或干phy端骨骼。肌肉疼痛的常见标志是夜间疼痛的发生几乎总是存在,从非甾体抗炎药产生令人满意的反应,可能会有关于体育活动的投诉。此外,它显示了计算机断层扫描(CT)和磁共振成像(MRI)等研究程序的典型迹象。Nidus,这是阴影图像诊断形成的主要标志,是OO的关键标志。这个来源通常被描绘成椭圆形的溶解性病变,测量1厘米平坦,周围有反应性骨化区域。诊断OO是费力的,因为这种情况经常与许多其他情况混淆,因此,测试和治疗可能会延迟和复杂化。关于OO诊断和替代条件区分的研究仍然很少。不幸的是,消融或切除可以说是治愈。改进的OO检测显示了及时诊断的可能性,减少患者的不适和副作用,减少不必要的治疗费用,和正确诊断的情况。
    Osteoid osteoma (OO) is a common benign ossifying lesion that is most prevalent among youth. Usually, it attacks the diaphyseal or metaphyseal bones that are tubular. The common hallmark of muscle pain is the reported occurrence of night pain that is nearly always present, yields satisfactory responses from nonsteroidal anti-inflammatory medications, and may be joined by complaints regarding physical activities. Also, it shows typical signs of study procedures like computed tomography (CT) and magnetic resonance imaging (MRI). A nidus, which is the primary marker in the diagnostic formation of shadowed images, is a crucial sign of an OO. This source is usually portrayed as an oval lytic lesion, measuring 1 cm flat and surrounded by a region of reactive ossification. It is laborious to diagnose OO since the condition is frequently confused with many other ones, and testing and therapy may be delayed and complicated as a result. There are still few studies on OO diagnosis and distinguishing of surrogate conditions. Unfortunately, either ablation or resection can be said to be the cure. Improved detection of OO shows the possibility for prompt diagnosis, fewer patient discomfort and side effects, less cost involved in unnecessary treatments, and a rightly diagnosed condition.
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  • 文章类型: Case Reports
    如果您在年轻患者中遇到无法解释的骨髓水肿病例,考虑骨样骨瘤(OO)的可能性。即使在重要结构附近有一个nidus,RFA可以安全地用于治疗OO。
    If you encounter an unexplained case of bone marrow edema in a young patient, consider the possibility of osteoid osteoma (OO). Even in the presence of a nidus near vital structures, RFA can safely be used to treat OO.
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  • 文章类型: Case Reports
    骨样骨瘤是一种良性原发性骨肿瘤,对长骨和椎骨有好感,当发生在罕见的地方,如距骨,提出了一个独特的挑战,占病例的5%至8%。早期成像努力检测其病灶,导致诊断延迟,特别是当非典型症状和以前的创伤使临床表现复杂化时。此病例报告说明了诊断挑战,并强调了闪烁显像指导的靶向计算机断层扫描(CT)在诊断距骨骨样骨瘤中的重要性。
    方法:一名23岁的男性出现了3年的慢性左踝关节疼痛,有创伤史.包括标准放射学和磁共振成像(MRI)在内的初步评估表明,距骨萎缩和腱鞘炎。但未能确认骨瘤。持续疼痛导致骨闪烁显像进一步研究,显示高度固定表明部分醛固酮营养不良。聚焦于闪烁显像识别区域的靶向CT扫描最终显示骨样骨瘤的病灶,使成功的手术干预和症状缓解。
    结论:距骨骨样骨瘤的诊断由于其非典型表现和罕见发生而经常被延迟。传统的成像技术可能会忽略肿瘤的病灶,强调有针对性的诊断方法的必要性。此病例证明了将闪烁显像与靶向CT相结合以增强早期诊断和治疗计划的价值,与MRI的有限诊断率形成对比,并强调CT对病灶检测的优越性。
    结论:距骨的骨样骨瘤提出了重大的诊断挑战。该病例报告强调了闪烁显像引导的靶向CT在识别病灶和促进及时手术治疗中的实用性。提倡采用多学科方法治疗非典型踝关节疼痛,尤其是有外伤史的患者.
    UNASSIGNED: Osteoid osteoma is a benign primary bone tumor with a predilection for the long bones and vertebrae, presenting a unique challenge when occurring in rare locations such as the talus, accounting for 5 to 8 % of cases. Early imaging struggles to detect its nidus, leading to diagnostic delays, especially when atypical symptoms and previous trauma complicate clinical presentations. This case report illustrates the diagnostic challenges and emphasizes the importance of targeted computed tomography (CT) guided by scintigraphy in diagnosing osteoid osteoma of the talus.
    METHODS: A 23-year-old male presented with chronic left ankle pain spanning three years, with a history of previous trauma. Initial evaluations including standard radiology and magnetic resonance imaging (MRI) suggested algodystrophy of the talus and tenosynovitis, but failed to identify the osteoma. Persistent pain led to further investigation with bone scintigraphy, revealing hyperfixation indicative of partial algodystrophy. Targeted CT scans focused on the scintigraphy-identified area ultimately revealed an osteoid osteoma\'s nidus, enabling successful surgical intervention and symptomatic relief.
    CONCLUSIONS: The diagnosis of osteoid osteoma in the talus is frequently delayed due to its atypical presentation and rare occurrence. Traditional imaging techniques may overlook the tumor\'s nidus, underscoring the necessity for targeted diagnostic approaches. This case demonstrates the value of integrating scintigraphy with targeted CT to enhance early diagnosis and treatment planning, contrasting with the limited diagnostic yield of MRI and underscoring CT\'s superiority for nidus detection.
    CONCLUSIONS: Osteoid osteoma of the talus poses significant diagnostic challenges. This case report highlights the utility of scintigraphy-guided targeted CT in identifying the nidus and facilitating prompt surgical management, advocating for a multidisciplinary approach to atypical ankle pain, especially in patients with a history of trauma.
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  • 文章类型: Case Reports
    尺侧腕部疼痛是一种复杂的临床情况,因为病变涉及腕部尺侧多个紧密定位的结构。导致尺侧腕关节疼痛的骨病变的发生率非常罕见。常用磁共振成像的有效性,在腕部尺侧的病理诊断中,这种骨性病变的诊断可能会受到限制,并可能导致漏诊。我们在此介绍了这种罕见的案例,该案例表现为尺侧腕关节疼痛。条件,提出了一个“诊断挑战”,需要计算机断层扫描来诊断和指导适当的管理。
    Ulnar side wrist pain is a complex clinical situation because of the pathologies involving multiple closely located structures on the ulnar side of the wrist. Incidence of osseous lesions leading to ulnar side wrist pain is very rare. The effectiveness of commonly employed Magnetic resonance imaging, for diagnosing the pathology in the ulnar side of the wrist might be limited in diagnosing such osseous lesions and can lead to missed diagnosis. We herein present such a rare case of Osteoid osteoma of the hook of hamate presenting as ulnar side wrist pain. The condition, presented a \"diagnostic challenge\", where it required Computed Tomography to diagnose and guide for appropriate management.
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  • 文章类型: Journal Article
    这项研究的目的是评估使用双极射频消融(RFA)治疗骨样骨瘤和患者治疗前后的生活质量。我们回顾性评估了2001年至2016年间接受骨样骨瘤双极RFA的患者。我们使用问卷评估患者治疗前后(治疗后4周和长期)的症状,包括10分制的疼痛严重程度和质量(1=无疼痛,10=剧烈疼痛),运动限制,疼痛相关的睡眠障碍,和必要的止痛药。此外,我们评估了技术成功,并发症,住院时间,和患者对治疗的满意度。这项研究包括62例患者(43例[69.4%]男性,26.2±13.2年)。平均病灶大小为5.7±2.6mm。技术成功率为100%。所有RFA均无任何并发症。一名患者出现复发,导致1.6%的复发率,通过另一届RFA成功治疗。平均住院时间为1.5±0.5天。共有36名患者(58.1%)参加了问卷调查,报告RFA前平均疼痛严重程度为8.2±1.6,而治疗后四周为3.4±3.0,治疗后平均为2.1±2.3,6.6年,(均p<0.001)。治疗后,31例(86.1%)患者无疼痛。大多数患者(n=34,94.4%)在治疗后运动限制减少或不存在(p<0.001)。患者满意率为91.7%。总之,双极RFA是一种安全有效的骨样骨瘤治疗方式,可通过减轻疼痛严重程度和运动限制来改善生活质量。
    The aim of this study was to evaluate treatment of osteoid osteomas using bipolar radiofrequency ablation (RFA) and patients\' quality of life before and after therapy. We retrospectively evaluated patients who underwent bipolar RFA of osteoid osteomas between 2001 and 2016. We assessed patients\' symptoms before and after treatment (four weeks after treatment and long-term) using a questionnaire including severity and quality of pain on a 10-point scale (1 = no pain, 10 = severe pain), motion restrictions, pain-related sleep disorders, and necessary pain medication. In addition, we evaluated technical success, complications, hospitalization length, and patients\' satisfaction with treatment. This study included 62 patients (43 [69.4%] males, 26.2 ± 13.2 years). Average nidus size was 5.7 ± 2.6 mm. The rate of technical success was 100%. All RFAs were performed without any complications. One patient showed a recurrence, resulting in a recurrence rate of 1.6%, which was successfully treated by another session of RFA. Average hospitalization length was 1.5 ± 0.5 days. A total of 36 patients (58.1%) participated in the questionnaire, reporting an average pain severity of 8.2 ± 1.6 before RFA compared to 3.4 ± 3.0 four weeks after and an average of 2.1 ± 2.3, 6.6 years after therapy, (both p < 0.001). After therapy, 31 (86.1%) patients had no pain. The majority of patients (n = 34, 94.4%) had reduced or absent motion restriction after therapy (p < 0.001). Patient satisfaction rate was 91.7%. In conclusion, bipolar RFA is a safe and effective treatment modality for osteoid osteomas and improves quality of life by reducing pain severity and motion restrictions.
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  • 文章类型: Journal Article
    骨样骨瘤(OO)是一种常见的,良性骨肿瘤.然而,没有OO与成骨不全症(OI)相关的病例报告,或OO的病理性骨折。一名患有OI的3岁女孩右胫骨干骨折。骨性融合在保守治疗4个月后完成;然而,18个月后,骨折部位出现自发性疼痛,没有任何理由。普通射线照片显示了一个新的明显的,直径1厘米的半透明圆形区域,只是与之前的骨折重叠。使用三维时间分辨对比增强磁共振血管造影获得的图像在早期显示强烈的中央增强,带有明显的Nidus,提示OO的诊断。第一次骨折十九个月后,在跳过的时候,患者在先前的骨折部位切除了胫骨骨干。这是一个非常罕见的OO案例,显然与OI共存并导致骨性骨折。在我们的案例中,OI中的骨脆性和OO部位的近期骨折的组合可能导致了再次骨折。
    Osteoid osteoma (OO) is a common, benign bone tumor. However, there are no case reports of OO associated with osteogenesis imperfecta (OI), or pathological fractures in OO. A 3-year-old girl with OI sustained a complete right tibial diaphyseal fracture. Bony fusion was completed after 4 months of conservative therapy; nevertheless, 18 months later spontaneous pain appeared at the fracture site, without any cause. Plain radiographs showed a newly apparent, rounded area of translucency 1 cm in diameter, just overlapping the previous fracture. Images obtained using three-dimensional time-resolved contrast-enhanced magnetic resonance angiography showed strong central enhancement in the early phase, with an apparent nidus, suggesting the diagnosis of OO. Nineteen months after the first fracture, while skipping, the patient refractured her tibial diaphysis at the site of the previous fracture. This is a very rare case of OO, apparently co-existing with OI and leading to a bony fracture. In our case, the combination of bone fragility in OI and a recent fracture at the site of the OO may have caused the re-fracture.
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  • 文章类型: Journal Article
    骨样骨瘤是骨骼的良性肿瘤,往往发生在长骨的骨干或干meta端。病变一般为骨内病变,临床症状模糊,因此被命名为“伟大的mimicker”。当位于骨膜下和近足关节时,不典型的临床表现和放射学可能导致延误或漏诊.进行误诊的手术会导致病变切除不完全和复发的风险。我们报告了一名15岁的男性,患有距骨骨膜下骨样骨瘤,被误诊为色素沉着绒毛结节性滑膜炎,并通过踝关节前切开术手术。从距骨颈的背侧去除直径为1厘米且具有硬橡胶稠度的结节性病变。病理标本符合骨膜下骨样骨瘤。患者的症状在术后早期迅速缓解。患者在第20个月随访时仍无症状,对照MRI未显示复发迹象。关节旁骨膜下骨样骨瘤的不典型放射学和临床表现引起误诊,延迟诊断,不完全切除和复发。在可疑色素性绒毛结节性滑膜炎的鉴别诊断中,重要的是要记住“骨膜下骨样骨瘤”。
    Osteoid osteoma is a benign tumor of the bone which tends to occur in diaphysis or metaphysis of the long bones. The lesion is generally intraosseous with vague clinical symptoms, hence given the name \"great mimicker\". When located subperiosteally and juxtaarticulary, atypical clinical presentation and radiological may lead to a delayed or missed diagnosis. Performing surgery with a misdiagnosis carries the risk of incomplete resection of the lesion and recurrence. We report the case of a 15-year-old male with a subperiosteal osteoid osteoma of the talus, who was misdiagnosed with pigmented villonodular synovitis and operated through anterior ankle arthrotomy. A nodular lesion 1 cm in diameter with hard rubber consistency was removed from the dorsal aspect of the talar neck. The pathological specimens were consistent with subperiosteal osteoid osteoma. The patient\'s symptoms resolved rapidly in the early postoperative period. The patient remained asymptomatic at the 20th-month follow-up and the control MRI revealed no signs of recurrence. Atypical radiological and clinical presentation of juxtaarticular subperiosteal osteoid osteomas cause misdiagnosis, delay in diagnosis, incomplete resection and recurrence. It is important to keep in mind \"juxtaarticular subperiosteal osteoid osteoma\" in the differential diagnosis of cases with suspected Pigmented Villonodular Synovitis.
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  • 文章类型: Journal Article
    目的:经皮CT引导射频消融(CT-RFA)是一种广泛接受的骨样骨瘤治疗方法。然而,由于存在一些弊端,CT-RFA的应用受到限制,例如辐射暴露,和全身麻醉的不便。这项研究的主要目的是评估TiRobot辅助的骨样骨瘤术中经皮RFA的安全性和有效性。
    方法:我们回顾性回顾了2021年3月至2022年4月在我们机构接受TiRobot系统引导下的骨样骨瘤经皮RFA治疗的21例患者的医疗档案。通过3DC臂在术中获得的三维图像被发送到TiRobot系统。设计了穿刺点和轨迹。然后在TiRobot的辅助下将引导销定位到病变处,并通过引导销将活检鞘插入病变中。对肿瘤进行活检以进行病理检查。然后通过活检鞘将RFA针插入病灶内进行热消融。提取相关并发症的数据,通过视觉模拟评分(VAS)评估术后1个月和1年的疼痛减轻。采用配对t检验比较术前、术后VAS评分。
    结果:患者包括17名男性和4名女性,平均年龄为19.5±10.4岁(范围3-45岁)。9例病变位于股骨,在9例胫骨上,在一个案例中,肱骨上,在一个案例中,跟骨上,在一个案例中,髋臼上。TiRobot辅助经皮RFA对所有21例患者均成功进行。未观察到术中或术后并发症。11例骨样骨瘤的病理诊断,但其他10例没有病理诊断。随访时间12~26个月,平均18.8个月。术后VAS评分均显著降低。平均VAS评分从术前的6.5降至术后1个月的0.5,术后1年的0.1。
    结论:作为定位和切除病灶的可靠技术,TiRobot辅助经皮RFA是治疗骨样骨瘤的安全有效选择。
    OBJECTIVE: Percutaneous CT-guided radiofrequency ablation (CT-RFA) is a widely accepted procedure for treatment of osteoid osteomas. However, the application of CT-RFA was restricted as a result of some drawbacks, such as radiation exposure, and inconvenience in general anesthesia. The primary aim of this study is to evaluate the safety and efficacy of intra-operative TiRobot-assisted percutaneous RFA of osteoid osteomas.
    METHODS: We retrospectively reviewed 21 medical files of patients who were treated with percutaneous RFA of osteoid osteomas guided by the TiRobot system in our institution between March 2021 and April 2022. The three-dimensional images obtained by a 3D C-arm intra-operatively were sent to the TiRobot system. The puncture point and trajectory were designed. Then the guide pin was positioned to the lesion with the assistance of TiRobot and the biopsy sheath was inserted into the lesion through the guide pin. The tumor was biopsied for pathological examination. Then the RFA needle was inserted into the nidus through the biopsy sheath for thermal ablation. Data were extracted on the associated complications, the reduction in pain at 1 month and 1 year postoperatively assessed by the visual analogue scale (VAS). A paired t-test was used to compare the pre-operative and post-operative VAS scores.
    RESULTS: The patients included 17 males and four females with a mean age of 19.5 ± 10.4 years (range 3-45 years). Lesions were located on the femur in nine cases, on the tibia in nine cases, on the humerus in one case, on the calcaneus in one case, and on the acetabulum in one case. TiRobot-assisted percutaneous RFA was successfully performed on all 21 patients. There was no intra-operative or post-operative complications observed. Pathological diagnosis of osteoid osteoma was obtained in 11 patients, but the other 10 cases were not pathologically diagnosed. The mean follow-up time was 18.8 months (range: 12-26 months).Post-operative VAS scores were reduced significantly in all cases. The mean VAS score decreased from 6.5 pre-operatively to 0.5 at 1 month post-operatively and to 0.1 at 1 year post-operatively.
    CONCLUSIONS: As a reliable technique for localizing and resection of nidus, TiRobot-assisted percutaneous RFA is a safe and effective option for the treatment of osteoid osteomas.
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  • 文章类型: Journal Article
    在这篇叙述性评论中,我们的目的是描述临床特征,诊断,以及影响儿童脊柱后部元素的常见原发性骨性肿瘤的治疗。我们搜索了PubMed,Mendeley,谷歌学者使用儿童脊柱原发性骨性肿瘤,脊柱后部的肿瘤,和单个肿瘤的名称。临床特征,调查,并分析了治疗方式,并准备了对该主题的叙述性审查。我们纳入了过去20年发表的54项研究。大多数是孤立的报告或病例系列。脊柱后部的肿瘤很少见。它们在儿童中很常见,其中大多数是良性的。疼痛和畸形是常见的表现。最好对抱怨背痛的儿童进行彻底的调查,以排除脊柱后部的原发性肿瘤。
    In this narrative review, we aim to describe the clinical features, diagnosis, and management of common primary osseous tumors affecting the posterior elements of the spine in children. We searched PubMed, Mendeley, and Google Scholar using the terms primary osseous tumors of the spine in children, tumors of the posterior elements of the spine, and names of individual tumors. The clinical features, investigations, and treatment modalities were analyzed, and a narrative review of the topic was prepared. We have included 54 studies published in the last 20 years. The majority are isolated reports or case series. Tumors of the posterior elements of the spine are rare. They are common in children and the majority of them are benign. Pain and deformity are common presentations. It is better to perform thorough investigations of children complaining of back pain to rule out primary tumors of the posterior elements of the spine.
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  • 文章类型: Case Reports
    骨样骨瘤是良性的,典型的皮质内病变最常影响长骨的骨干。通过施用非甾体类抗炎药(NSAIDs)可以缓解夜间疼痛和特征性症状,可以帮助诊断骨样骨瘤。我们报告了一例18岁男孩,其尺骨鹰嘴窝有骨样骨瘤,临床表现不典型。最初的表现是关节炎样症状,如局部发热,运动疼痛而不是休息时的疼痛,和有限的运动范围。值得注意的是,NSAIDs根本不能有效缓解他的症状。磁共振成像显示肘关节周围骨髓水肿。症状对保守治疗有抵抗力,因此,需要手术切除.组织病理学检查显示,病变由相互吻合的编织骨和类骨组织组成。结合肿瘤大小小于2厘米,临床病理,肿瘤被诊断为骨样骨瘤。术后疼痛立即缓解,术后2个月活动范围恢复。手术后一年,患者未出现肿瘤复发或肘部疼痛加重,肘部活动范围很广.在青少年和年轻人的肘关节关节炎的鉴别诊断中,应考虑骨样骨瘤,这是骨样骨瘤发病的高峰年龄。
    Osteoid osteomas are benign, typically intracortical lesions most often affecting the diaphysis of long bones. Nocturnal pain and characteristic symptoms that are relieved by administration of non-steroidal anti-inflammatory drugs (NSAIDs) are present and can help in the diagnosis of osteoid osteoma. We report a case of 18-year-old boy with an osteoid osteoma in the olecranon fossa with an atypical clinical manifestation. The initial manifestation was arthritis-like symptoms such as local heat, motion pain rather than pain at rest, and limited range-of-motion. Notably, NSAIDs were not effective at all for relieving his symptoms. Magnetic resonance imaging showed bone marrow edema around the elbow joint. The symptoms were resistant to conservative treatments, and thus, surgical resection was required. Histopathological examination showed that the lesion consisted of woven bones and osteoid tissues that anastomosed with each other. Combined with a tumor size that was less than 2 cm, clinicopathologically, the tumor was diagnosed as an osteoid osteoma. The pain was immediately relieved after the operation, and range-of-motion recovered at 2 months postoperatively. At 1 year after the surgery, the patient did not exhibit recurrence of the tumor or exacerbation of elbow pain and had a full range of elbow motion. Osteoid osteoma should be considered for the differential diagnosis of arthritis of the elbow in patients who are adolescents and young adults, which is the peak age of onset for osteoid osteoma.
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