Oral Hemorrhage

  • 文章类型: Case Reports
    背景:下颌动静脉畸形(AVM)很少见。我们的工作旨在介绍下颌AVM引起的急性口腔出血患者的乙醇栓塞。
    方法:一名35岁无凝血障碍的妇女接受了拔牙治疗,术中发生急性口腔出血。影像学检查显示血管块增强,下颌骨内部骨破坏。血管造影最终证实了高血流性质和AVM的诊断。
    结果:在介入过程中,首先将线圈施加到扩张的流出静脉中,以减慢下颌AVM的血流速度。以多推注方式注入无水乙醇以破坏AVM的nidus。在12个月的血管造影复查中,她的下颌骨病变稳定,期间无进一步出血.
    结论:乙醇栓塞治疗是一种侵入性较小的,更精确,和快速行动方法管理下颌的AVM和相关的急诊医学。
    BACKGROUND: Mandibular arteriovenous malformation (AVM) is rare. Our work aims to introduce the ethanol embolization of a patient suffering from acute oral hemorrhage induced by mandibular AVM.
    METHODS: A 35-year-old woman without coagulopathy underwent tooth extraction, and the acute oral bleeding occurred intraoperatively. Imaging examinations indicated the enhancement of vascular mass with bone destruction inside the mandible. Angiography finally confirmed the high blood flow nature and the diagnosis of AVM.
    RESULTS: During the interventional procedure, the coils were first applied into the dilated outflowing vein to slow down the blood flow rate of mandibular AVM. Absolute ethanol was injected in a multi-bolus modality to destroy the nidus of AVM. Her mandibular lesion had been stable in the 12-month re-examined angiography, no further bleeding occurred during the period.
    CONCLUSIONS: Ethanol embolotherapy was a less invasive, more precise, and quick-action approach managing AVM of the jaw and related emergency medicine.
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  • 文章类型: Journal Article
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  • 文章类型: Journal Article
    目的:比较2018年欧洲牙周病联合会/美国牙周病学会(EFP/AAP)分类与其他病例定义估计的牙龈炎患病率,并评估该分类系统在区分与牙龈炎相关的社会人口统计学和临床因素方面的能力。
    方法:根据社区牙周指数,对1134名12岁青少年进行了多阶段随机抽样,接受了全口检查。在基线时收集社会经济和临床变量。根据以下标准考虑牙龈炎:(a)出血部位≥10%(2018年EFP/AAP标准);(b)出血部位≥15%;(c)平均全口出血部位。调整后的多水平泊松回归评估了基线时的独立变量与2年随访时牙龈炎的每种定义之间的关联。
    结果:742名14岁青少年在随访时被重新评估。根据出血阈值的10%,牙龈炎的患病率为28.7%。2018年EFP/AAP标准和其他定义显示,低收入青少年以及牙菌斑和未经治疗的龋齿水平较高的人群,牙龈炎的患病率和平均值较高。尽管如此,出血部位的阈值≥15%时,相关性最强.
    结论:与15%阈值和平均全口出血部位相比,2018年EFP/AAP病例对牙龈炎的定义显示出相似的判别有效性。
    结论:2018年EFP/AAP分类允许区分重要的危险因素,应用于建立大规模治疗计划的优先级。
    OBJECTIVE: To compare the prevalence of gingivitis estimated by the 2018 European Federation of Periodontology/American Academy of Periodontology (EFP/AAP) classification with the other case definitions and assess the ability of this classification system in discriminating sociodemographic and clinical factors associated with the presence of gingivitis in a cohort study.
    METHODS: A multistage random sample of 1134 12-year-old adolescents was submitted to a full-mouth examination according to the Community Periodontal Index. Socioeconomic and clinical variables were collected at baseline. Gingivitis was considered according to the following criteria: (a) ≥ 10% of bleeding sites (the 2018 EFP/AAP criteria); (b) ≥ 15% of bleeding sites; and (c) the mean full-mouth bleeding sites. Adjusted multilevel Poisson regression assessed the association between independent variables at baseline and each definition of gingivitis at 2-year follow-up.
    RESULTS: Seven hundred forty-two 14-year-old adolescents were re-revaluated at follow-up. The prevalence of gingivitis was 28.7% according to 10% of bleeding threshold. The 2018 EFP/AAP criteria and other definitions showed higher prevalence and mean of gingivitis for low-household income adolescents and for those with higher levels of dental plaque and untreated dental caries. Nonetheless, the highest strengths of association were observed for the threshold of ≥ 15% of bleeding sites.
    CONCLUSIONS: The 2018 EFP/AAP case definition of gingivitis showed a similar discriminant validity compared to the 15% threshold and the mean full-mouth bleeding sites.
    CONCLUSIONS: The 2018 EFP/AAP classification allows the discrimination of important risk factors and should be used for the establishment of priorities for large-scale therapeutic programs.
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  • 文章类型: Meta-Analysis
    这项网络荟萃分析旨在全面评估现有文献中关于口服抗血栓治疗患者使用不同止血剂进行拔牙的情况。旨在确定在出血控制方面表现最佳/最差的药物。考虑到这些患者有更高的出血风险,选择正确的止血剂至关重要。在完成文献检索后,纳入了23篇随机临床试验文章。与常规方法相比,氰基丙烯酸酯组织粘合剂显示术后出血事件的几率降低(即,纱布/棉压力,缝线),具有统计学意义的趋势(OR0.03,P=0.051)。氨甲环酸是唯一显示术后出血事件发生风险显著降低的药物(OR0.27,P=0.007)。有趣的是,壳聚糖牙科敷料和胶原蛋白塞止血时间最短。然而,它们在所有止血剂中排名最后,关于出血事件,揭示比传统措施更高的几率。因此,结论是,使用氰基丙烯酸酯组织粘合剂和氨甲环酸在减少拔牙后的术后出血事件方面具有良好的效果。虽然壳聚糖牙科敷料和胶原蛋白显示更快的时间达到止血,它们导致了更高的出血事件发生率.
    This network meta-analysis was done to thoroughly evaluate the available literature on the use of different hemostatic agents for dental extraction in patients under oral antithrombotic therapy, aiming to identify the agent with the best/worst performance in bleeding control. Considering that such patients have a higher risk of bleeding, choosing the right hemostatic is essential. Twenty-three randomized clinical trials articles were included after completing the literature search. Cyanoacrylate tissue adhesive showed a reduction in the odds of postoperative bleeding events compared with conventional methods (i.e., gauze/cotton pressure, sutures), with a tendency toward a statistical significance (OR 0.03, P = 0.051). Tranexamic acid was the only agent that demonstrated a significantly lower risk of developing postoperative bleeding events (OR 0.27, P = 0.007). Interestingly, chitosan dental dressing and collagen plug had the shortest time to reach hemostasis. However, they ranked last among all hemostatic agents, regarding bleeding events, revealing higher odds than conventional measures. Therefore, it is concluded that the use of cyanoacrylate tissue adhesive and tranexamic acid gives favorable results in reducing postoperative bleeding events following dental extractions. Although chitosan dental dressing and collagen exhibited a faster time to reach hemostasis, they led to a higher occurrence of bleeding events.
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  • 文章类型: Case Reports
    由于并发症的高死亡率,食管梗阻代表内镜下急诊。包括穿孔和气道受损。虽然通常由食物或异物摄入引起,食管凝块是一种罕见的梗阻病因。我们介绍了在吻合口狭窄和慢性抗凝治疗的情况下,由于拔牙后由于口腔出血而形成凝块而引起的心房颤动,导致食管阻塞。凝块取出是通过内窥镜抽吸完成的,并对吻合口狭窄进行球囊扩张以防止复发。我们的案例说明了考虑口腔出血的重要性,治疗性抗凝,和食管狭窄是由于凝块形成导致食管阻塞的危险因素,以便及时诊断和治疗这种潜在的内镜急诊。
    Esophageal obstruction represents an endoscopic emergency owing to the high mortality rate associated with complications, including perforation and airway compromise. While typically caused by food or foreign body ingestion, esophageal clot represents a rare etiology of obstruction. We present a case of esophageal obstruction in the context of an anastomotic stricture and chronic anticoagulation for atrial fibrillation caused by clot formation due to oral hemorrhage after dental extractions. Clot retrieval was accomplished via endoscopic suction, and balloon dilation of the anastomotic stricture was performed to prevent recurrence. Our case illustrates the importance of considering oral hemorrhage, therapeutic anticoagulation, and esophageal strictures as risk factors for esophageal obstruction due to clot formation in order to make a timely diagnosis and treatment of this potential endoscopic emergency.
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  • 文章类型: Journal Article
    背景:这项体内研究旨在阐明舌下动脉(SLA)相对于下颌骨的位置,并推断在种植牙手术过程中受伤的潜在风险。
    方法:回顾了在德岛大学医院接受治疗的50例无牙患者(100侧)的口腔的对比增强计算机断层扫描图像。对垂直于牙槽脊的弯曲平面重建图像进行处理,并将其分类为磨牙,前磨牙,犬,和门牙区域。确定了SLA及其分支机构,测量下颌骨到SLA的距离。
    结果:SLA位于磨牙中的下颌骨附近(<2mm),前磨牙,犬,和门牙段在12.0%(95%置信区间5.6%-18.4%),20.6%(12.6%-28.7%),30.5%(21.3%-39.8%),和41.8%(28.8%-54.9%)的病例,分别。在50%的病例中,SLA位于磨牙和前磨牙区域的颅尾至下颌管上壁±3mm范围内,在其他病例中,在犬科和门牙区域的颅尾至肌舌骨脊±5mm范围内,没有性别或年龄差异。由于肺泡吸收,从牙槽到SLA的垂直距离受性别和年龄的影响,表明牙槽脊不是预测SLA位置的可靠参考。
    结论:由于在种植牙期间一直存在SLA损伤的风险,并且无法确认患者的SLA途径,临床医生必须避免损伤舌下软组织。
    BACKGROUND: This in vivo study aimed to clarify the position of the sublingual artery (SLA) relative to the mandibular bone and to infer the potential risk for injury during dental implant surgery.
    METHODS: Contrast-enhanced computed tomography images of the mouth of 50 edentulous patients (100 sides) treated at Tokushima University Hospital were reviewed. Curved planar reconstructed images perpendicular to the alveolar ridge were processed and classified into molar, premolar, canine, and incisor regions. The SLA and its branches were identified, and the distance from the mandible to the SLA was measured.
    RESULTS: The SLA was located close to the mandible (<2 mm) in the molar, premolar, canine, and incisor segments in 12.0% (95% confidence interval 5.6%-18.4%), 20.6% (12.6%-28.7%), 30.5% (21.3%-39.8%), and 41.8% (28.8%-54.9%) cases, respectively. The SLA was located within ±3 mm craniocaudally to the upper wall of the mandibular canal in the molar and premolar regions in 50% of cases and within ±5 mm craniocaudally to the mylohyoid ridge in the canine and incisor regions in the other cases, with no sex or age-related differences. The vertical distance from the alveolar ridge to the SLA was influenced by sex and age owing to alveolar resorption, indicating that the alveolar ridge is not a reliable reference for predicting SLA position.
    CONCLUSIONS: As the risk of SLA injury always exist during dental implant placement and there is no way to confirm the SLA pathways in a patient, clinicians must avoid injuring the sublingual soft tissue.
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  • 文章类型: Case Reports
    下颌动静脉畸形(AVM)是罕见的病变,可伴有危及生命的出血。血管内栓塞可以挽救这些患者的生命。我们讨论了一名下颌AVM患者,最初提交了大量口腔出血的报告。病变仅通过动脉途径部分栓塞,因为Nidus无法完全穿透。鉴于同一部位72小时内再次出血,通过联合进行第二次栓塞手术,经动脉和经静脉入路。线圈和玛瑙被用作栓塞剂。通过联合方法实现完全栓塞。在1年的随访中没有看到进一步的出血事件。下颌AVM的血管内栓塞可能在技术上具有挑战性,因此,良好的解剖学知识以及可能的技术修改对于实现病变的完全消除,最大限度地提高栓塞的益处和避免大的根治性手术至关重要。
    Mandibular arteriovenous malformations (AVMs) are rare lesions which can present with life-threatening haemorrhage. Endovascular embolisation can be life saving for these patients. We discuss a patient of mandibular AVM, who initially presented with reports of massive oral bleeding. The lesion was only partially embolised via transarterial route, as the nidus could not be penetrated completely. In view of rebleeding within 72 hours from the same site, a second embolisation procedure was done via combined, transarterial and transvenous approaches. Coils and onyx were used as embolising agents. Complete embolisation was achieved via combined approach. No further bleeding episodes were seen at 1-year follow-up. Endovascular embolisation of mandibular AVMs can be technically challenging and, hence, a sound knowledge of the anatomy as well as the possible modification of technique is essential to achieve complete obliteration of the lesion and to maximise the benefit of embolisation and to avoid major radical surgery.
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  • 文章类型: Journal Article
    Badham于1967年首次将大疱性出血心绞痛(ABH;也称为口腔大疱性出血或“良性出血性大疱性口炎”)定义为由于机械外伤性冲洗而在口咽粘膜上反复形成血泡。可能与先前由于一般医学发现(如高血压)引起的粘膜损伤有关,糖尿病或长期吸入糖皮质激素尚未得到证实。
    Angina bullosa haemorrhagica (ABH; also: bullosa haemorrhagica oralis or \"benign hemorrhagic bullous stomatitis\") was first defined by Badham in 1967 as recurrent formation of blood blisters on the oropharyngeal mucosa as a result of mechanically traumatic irri- tation. A possible connection with previous damage to the mucosa due to general medical findings such as hypertension, diabetes mellitus or chronic inhalation of corticosteroids has not yet been confirmed.
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  • 文章类型: Case Reports
    大疱性出血心绞痛是一种相对罕见的疾病,其特征是口腔粘膜中充满血液的上皮下病变,是特发性的,不是由全身性疾病或止血异常引起的。中老年患者通常会受到影响,并且病变会自发愈合,而不会留下疤痕。口咽部快速扩张的出血性水疱可引起上呼吸道阻塞,所以尽快识别病变是至关重要的。因为它的稀有性,我们想重点介绍一名42岁男性患者,该患者表现为出血性大疱,并伴有口腔黏膜不明显的局部创伤,并强调大疱性心绞痛是一种罕见但可识别的病变,临床医生应注意.
    Angina bullosa haemorrhgica is a relatively uncommon condition characterized by blood-filled subepithelial lesions in the oral mucosa that is idiopathic and not caused by a systemic disease or a hemostatic abnormality. Middle-aged and elderly patients are usually affected and lesions heal spontaneously without scarring. A rapidly expanding hemorrhagic blister in the oropharynx can induce upper airway obstruction, so recognizing the lesion as soon as possible is essential. Because of its rarity, we wanted to highlight a 42-year-old male patient who presented with hemorrhagic bullae associated with insignificant local trauma in the oral mucosa and to emphasize that Angina bullosa haemorrhagica is a rare but recognizable lesion that clinicians should be aware of.
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  • 文章类型: Letter
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