■关于CRP水平与牙源性感染之间关系的研究似乎是有限的。这项研究的目的是确定不同类型的牙源性感染之间的CPR水平差异。
■研究了所有连续诊断和治疗符合纳入标准的牙源性牙槽和筋膜间隙感染的患者。收集的数据是年龄,性别,烟草使用,酒精摄入量,和药物滥用。其他收集的数据是疼痛,刺耳,吞咽困难,滥用抗生素,预先存在的医疗状况,脉搏率,血压,呼吸频率,体温,白细胞,牙源性感染的类型,治疗类型,住院时间和C反应蛋白。所有分析均使用IBMSPSS21.0版(IBMCorp,纽约,美国)。P-值小于5%被认为是统计学上显著的。
■本研究共纳入44例患者,平均年龄为45.3±1.39岁,范围为10至60岁。与无疼痛史患者相比,有疼痛史阳性患者的C反应蛋白明显更高(P=0.01)。筋膜间隙感染患者的C反应蛋白水平高于牙槽炎患者,差异有统计学意义(P=0.02)。同样,与住院时间少于同日的患者相比,住院时间超过5天的患者的C反应蛋白为17.5mg/dl(P=0.03)。
■C反应蛋白的总平均值75.4±3.53mg/dl大于临界水平,而白细胞计数的9.62X109/L低于参考值。有疼痛的病人,牙源性感染后,筋膜间隙感染和在医院停留超过五天的C反应蛋白水平较高。
UNASSIGNED: It appears that studies on the association between CRP levels and odontogenic infections are limited. The aim of this study is to determine the difference in CPR levels between the different types of odontogenic infections.
UNASSIGNED: All consecutive patients that were diagnosed and treated for dentoalveolar and fascial space infections of odontogenic origin that met the inclusion criteria were studied. The data collected were age, gender, tobacco use, alcohol intake, and drug abuse. Other collected data were pain, trismus, dysphagia, antibiotics abuse, pre-existing medical condition, pulse rate, blood pressure, respiratory rate, body temperature, white blood cell, type of odontogenic infection, type of treatment, length of hospital stay and C-reactive protein. All analysis were done using IBM SPSS version 21.0 (IBM Corp, New York, USA). P- Value less than 5% was considered statistically significant.
UNASSIGNED: A total of 44 patients with a mean age of 45.3±1.39 years ranging from 10 to 60 years were enrolled in this study. The C-reactive protein was significantly higher among patients with positive history of pain compared to those without pain (P = 0.01). The patients with fascial space infection had C-reactive protein levels higher than those with dentoalveolar infection and the difference in their means was statistically significant (P = 0.02). Likewise, the C-reactive protein was 17.5mg/dl significantly higher in the patients that stayed more than 5days in the hospital compared to those that stayed less than the same days(P = 0.03).
UNASSIGNED: The total mean of C-reactive protein of 75.4±3.53 mg/dl was greater than the critical level while the 9.62 X 109/L of WBC counts was lower than that of the reference value. Patients that had pain, fascial space infection and stayed more than five days in the hospital had higher levels of C-reactive protein following odontogenic infections.