目的:本研究旨在确定年龄的影响,性别,生殖状态,头骨类型,和鼻泪管(NLD)通畅对正常犬的泪液产生和泪膜破裂时间(TBUT)的影响。
方法:本研究评估了82只健康成年犬的眼科数据。
方法:年龄,性别,品种,并记录生殖状况。在所有狗中评估Schirmer撕裂试验(STT)和TBUT。和干涉测量法可用于选定的狗。Jones检验用于评估NLD通畅性。计算每只狗的头指数(CI)(头骨宽度/头骨长度×100)。
结果:右眼(OD)和左眼(OS)的STT结果的平均值(SD)分别为20.6(2.7)和20.2(2.7)mm/min,分别。所有狗的OD和OS的平均(SD)TBUT值分别为6.5(2.5)和6.1(2.3)mm/min,分别。性别和生殖状况对STT和TBUT无显著影响(P[OU]>0.05)。颅骨类型显著影响双眼TBUT(P(OD)=0.01,P(OS)=0.003),但对STT无影响(P[OU]>0.3)。年龄与STT和TBUT均无相关性(P[OU]>0.05)。两眼STT和TBUT均无相关性(P[OU]>0.2)。NLD通畅对STT或TBUT无显著影响(P[OU]>0.1)。
结论:这项研究的结果表明,短脑品种的TBUT值低于非短脑品种。在具有低TBUT值的狗中观察到STT值的代偿性增加。
OBJECTIVE: The present study aimed to determine the effects of age, sex, reproductive status, skull type, and nasolacrimal duct (NLD) patency on tear production and tear film breakup time (TBUT) in normal dogs.
METHODS: The ophthalmic data of 82 healthy adult dogs were evaluated in this study.
METHODS: Age, sex, breed, and reproductive status were recorded. Schirmer tear test (STT) and TBUT were assessed in all dogs, and interferometry was available for the selected dogs. The Jones test was used to evaluate NLD patency. The cephalic index (CI) was calculated for each dog (skull width/skull length ×100).
RESULTS: Mean (SD) values for the STT results for the right (OD) and left (OS) eyes were 20.6 (2.7) and 20.2 (2.7) mm/min, respectively. Mean (SD) TBUT values for OD and OS were 6.5 (2.5) and 6.1 (2.3) mm/min in all dogs, respectively. Sex and reproductive status had no significant effect on STT and TBUT (P[OU] > 0.05). Skull type significantly affected TBUT in both eyes (P(OD) = 0.01, P(OS) = 0.003), but had no effect on STT (P[OU] > 0.3). Age had no correlation with STT and TBUT in either eye (P[OU] > 0.05). STT and TBUT had no correlation in either eye (P[OU] > 0.2). NLD patency had no significant effect on STT or TBUT (P[OU] > 0.1).
CONCLUSIONS: The results of this study showed lower TBUT values in brachycephalic breeds than in non-brachycephalic breeds. A compensatory increase in STT values was observed in dogs with low TBUT values.