■在日常练习中,我们遇到了阻塞性睡眠呼吸暂停综合征(OSAS)患者,尽管有相似的呼吸暂停低通气指数(AHI),但需要不同水平的气道正压通气(PAP).我们旨在确定有助于确定PAP治疗水平的参数。
■对548例接受多导睡眠图和PAP滴定的患者数据进行回顾性分析。根据OSAS严重程度将患者分为几组(轻度,中度,和严重),并确定每组的平均压力,之后,将患者进一步分为要求PAP低于平均值的患者和要求PAP高于平均值的患者。
■轻度患者的平均最佳PAP水平,中度,重度OSAS组为7.4±2.3、8.6±2.4和9.8±2.9cmH2O,分别。在中度和重度OSAS组中,需要高压的亚组仰卧AHI较高,更长的呼吸暂停时间,与需要低压的亚组相比,SaO2<90%的时间更长。
■在中度和重度OSAS患者中,较长的呼吸暂停持续时间和较高的仰卧位AHI与较高的PAP水平相关。
UNASSIGNED: In daily practice, we encounter with obstructive sleep apnoea syndrome (OSAS) patients who require different levels of positive airway pressure (PAP) despite having a similar apnoea-hypopnea index (AHI). We aimed to determine the parameters contributing to the determination of the therapeutic level of PAP.
UNASSIGNED: Data on 548 patients who underwent polysomnography and PAP titration were analysed retrospectively. Patients were divided into groups according to OSAS severity (mild, moderate, and severe) and the mean pressure in each group was determined, after which patients were further divided into those who required a PAP below the mean and those who required a PAP above the mean.
UNASSIGNED: The mean optimal PAP level in the mild, moderate, and severe OSAS groups was 7.4 ± 2.3, 8.6 ± 2.4, and 9.8 ± 2.9 cm H2O, respectively. In the moderate and severe OSAS group, the subgroup that needed high pressure had a higher supine AHI, a longer apnoea time, and a longer SaO2 <90% time as compared with the subgroup that needed low pressure.
UNASSIGNED: A longer apnoea duration and a higher supine AHI are associated with a higher PAP level in patients with moderate and severe OSAS.