目标:开发一种简单的,主观,以及可靠的异维甲酸诱导的动脉造影变化的分级量表。
方法:在分析了从全身异维甲酸使用者获得的囊图图像后,提出了一个分级量表,并命名为“细部图健康评分”。“评分范围从1到3,腺体反射率和可识别的边缘降低。共有11名医学专业人员被要求使用拟议的量表对从异维A酸使用者获得的10个眼图图像进行分级,并分为三组:(A)具有眼图经验的眼科医生,(B)没有眼动脉造影经验的眼科医生,和(C)放射科医师。确定了kappa统计量以测试评估者间的可靠性。
结果:总κ约为0.64。A组的kappa得分,B,C分别为0.78、0.59和0.90。2年级的kappa分数最低(A为0.62、0.35和0.82,B,C,分别)和3级最高(A为0.78、0.90和1.0,B和C,分别)。此外,C组的kappa得分最高,B组最低。
结论:指数健康评分表现出良好的评分者间可靠性,特别是在严重的情况下。
OBJECTIVE: To develop a simple, subjective, and reliable grading scale for isotretinoin-induced meibography changes.
METHODS: After analyzing meibography images obtained from systemic isotretinoin users, a grading scale was proposed and named \"meibography health score.\" The score ranged from 1 to 3, with decreasing gland reflectivity and identifiable margins. A total of 11 medical professionals were asked to grade 10 meibography images obtained from isotretinoin users using the proposed scale and were divided into three groups: (A) ophthalmologists with experience with meibography, (B) ophthalmologists with no experience with meibography, and (C) radiologists. The kappa statistic was determined to test interrater reliability.
RESULTS: The overall kappa was approximately 0.64. The kappa scores for Groups A, B, and C were 0.78, 0.59, and 0.90, respectively. Grade 2 had the lowest kappa scores (0.62, 0.35, and 0.82 for A, B, and C, respectively) and grade 3 the highest (0.78, 0.90, and 1.0 for A, B and C, respectively). Furthermore, Group C had the highest kappa scores and Group B the lowest.
CONCLUSIONS: The meibography health score exhibited good interrater reliability, particularly in severe cases.