■印度尼西亚每年因结核病(TB)死亡的人数近20万,高于COVID-19。与脊髓结核相关的问题是维生素D缺乏,神经功能缺损,日常生活活动中断和长期抗结核治疗(24个月)。维生素D具有抗炎作用,保持血管健康,并增加钙水平。
方法:我们报告了130例系列脊柱结核,神经问题,维生素D缺乏;手术后,抗结核药物和维生素D佐剂12个月。结核病诊断通过放射学证实,微生物和组织病理学研究。
■治疗时间短于标准常规治疗后,患者运动功能100%正常,3%刚度,融合率为97.4%,98.5%正常维生素D,基于Oswestry残疾指数(ODI)评分的最小残疾,和基于日本骨科协会(JOA)评分的正常功能。
结论:维生素D应被视为脊髓结核治疗的辅助治疗,尽管仍需要进一步的研究来确定其疗效和安全性。手术和抗结核药物的施用仍然是标准程序。
UNASSIGNED: Deaths from tuberculosis (TB) in Indonesia are nearly 200,000 per year and higher than those from COVID-19. The problems associated with spinal TB are vitamin D deficiency, neurological deficit, disruption of daily living activities and long-term anti-TB treatment (24 months). Vitamin D acts as an anti-inflammatory, maintains vascular health, and increases calcium levels.
METHODS: We reported 130 cases series spinal TB, neurological problems, vitamin D deficiencies; after surgery, anti-TB drugs and vitamin D adjuvant for 12 months. A TB diagnosis was confirmed by radiology, microbial and histopathology investigations.
UNASSIGNED: After the treatment is shorter than standard conventional, patients had 100 % normal motor function, 3 % stiffness, 97.4 % fusion rate, 98.5 % normal vitamin D, minimal disability based on Oswestry Disability Index (ODI) scores, and normal function based on Japanese Orthopaedic Association (JOA) scores.
CONCLUSIONS: Vitamin D should be considered an adjuvant in spinal TB treatment, although further research is still needed to determine its efficacy and safety. Surgery and the administration of anti-TB drugs are still the standard procedures.