NSQIP

NSQIP
  • 文章类型: Journal Article
    在西方国家,食管腺癌的发病率正在增加。经食管切除术(THE)已转向微创方法。这项研究将我们机构的食管腺癌切除术机器人THE的结果与美国外科医生学会国家外科质量改进计划(ACSNSQIP)的预测指标进行了比较。经机构审查委员会(IRB)批准,我们前瞻性随访了从2012年到2023年接受机器人THE的83例患者。使用ACSNSQIP手术风险计算器确定预测结果。我们的结果与这些预测结果和ACSNSQIP报道的经食管切除术的一般结果进行了比较。其中包括多种手术方法。患者的中位年龄为70岁,体重指数(BMI)为26.4kg/m2,男性患病率为82%。中位住院时间为7天。任何并发症和住院死亡率分别为16%和5%,分别。7名患者(8%)在术后30天内再次入院。中位生存期预计超过95个月。我们的结果通常与预测的ACSNSQIP指标一致或超过预测的指标。超过95个月的中位生存期凸显了机器人THE在食管腺癌切除术中的潜在有效性。有必要进一步探索其长期生存益处和结果,以及提供机器人和其他手术方法之间更直接比较的研究。
    Esophageal adenocarcinoma incidence is increasing in Western nations. There has been a shift toward minimally invasive approaches for transhiatal esophagectomy (THE). This study compares the outcomes of robotic THE for esophageal adenocarcinoma resection at our institution with the predicted metrics from the American College of Surgeons National Surgical Quality Improvement Program (ACS NSQIP). With Institutional Review Board (IRB) approval, we prospectively followed 83 patients who underwent robotic THE from 2012 to 2023. Predicted outcomes were determined using the ACS NSQIP Surgical Risk Calculator. Our outcomes were compared with these predicted outcomes and with general outcomes for transhiatal esophagectomy reported in ACS NSQIP, which includes a mix of surgical approaches. The median age of patients was 70 years, with a body mass index (BMI) of 26.4 kg/m2 and a male prevalence of 82%. The median length of stay was 7 days. The rates of any complications and in-hospital mortality were 16% and 5%, respectively. Seven patients (8%) were readmitted within a 30-day postoperative window. The median survival is anticipated to surpass 95 months. Our outcomes were generally aligned with or surpassed the predicted ACS NSQIP metrics. The extended median survival of over 95 months highlights the potential effectiveness of robotic THE in the resection of esophageal adenocarcinoma. Further exploration into its long-term survival benefits and outcomes is warranted, along with studies that provide a more direct comparison between robotic and other surgical approaches.
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  • 文章类型: Journal Article
    尽管已有几项研究描述了门诊全髋关节置换术(THA)后并发症的危险因素,缺乏描述此类并发症发生时间的数据.
    在2012-2019年国家外科质量改进计划数据库中确定了接受门诊或住院原发性THA的患者。对于9种不同的30天并发症,确定了术后中位诊断日.多变量回归用于比较门诊和住院组之间每种并发症的风险。多变量Cox比例风险模型用于评估组间各不良事件发生时间的差异。
    门诊THA后,再次入院的中位诊断天数为12.5(四分位距5-22),手术部位感染15(2-21),尿路感染13.5(6-19.5),深静脉血栓形成13(8-21),心肌梗死4.5(1-7),肺栓塞15(8-25),败血症16(9-26),行程2(0-7),肺炎6.5(3-10)。在多变量回归中,门诊患者的再入院相对风险(RR)较低(RR=0.73),手术部位感染(RR=0.72),和肺炎(RR=0.1),所有P<0.05。在多变量cox比例危险建模中,门诊患者与住院患者之间各并发症发生时间差异无统计学意义(P>.05).
    门诊THA后并发症的发生时间与住院手术相似。在此处确定的高危时间段内,应考虑降低门诊THA后每种并发症的诊断测试阈值。虽然极为罕见,这对于灾难性不良事件尤其重要,这往往发生在出院后的早期。
    UNASSIGNED: Although there have been several studies describing risk factors for complications after outpatient total hip arthroplasty (THA), data describing the timing of such complications is lacking.
    UNASSIGNED: Patients who underwent outpatient or inpatient primary THA were identified in the 2012-2019 National Surgical Quality Improvement Program database. For 9 different 30-day complications, the median postoperative day of diagnosis was determined. Multivariable regressions were used to compare the risk of each complication between outpatient vs inpatient groups. Multivariable Cox proportional hazards modeling was used to evaluate the differences in the timing of each adverse event between the groups.
    UNASSIGNED: After outpatient THA, the median day of diagnosis for readmission was 12.5 (interquartile range 5-22), surgical site infection 15 (2-21), urinary tract infection 13.5 (6-19.5), deep vein thrombosis 13 (8-21), myocardial infarction 4.5 (1-7), pulmonary embolism 15 (8-25), sepsis 16 (9-26), stroke 2 (0-7), and pneumonia 6.5 (3-10). On multivariable regressions, outpatients had a lower relative risk (RR) of readmission (RR = 0.73), surgical site infection (RR = 0.72), and pneumonia (RR = 0.1), all P < .05. On multivariable cox proportional hazards modeling, there were no statistically significant differences in the timing of each complication between outpatient vs inpatient procedures (P > .05).
    UNASSIGNED: The timing of complications after outpatient THA was similar to inpatient procedures. Consideration should be given to lowering thresholds for diagnostic testing after outpatient THA for each complication during the at-risk time periods identified here. Although extremely rare, this is especially important for catastrophic adverse events, which tend to occur early after discharge.
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  • 文章类型: Journal Article
    背景:与年轻患者相比,认知功能障碍/痴呆(CID)和跌倒在老年人中更常见。这项研究旨在分析CID或跌倒史与在全国范围内接受大型腹内手术的老年人术后结局的关系。
    方法:我们回顾性分析了美国外科医师学会-国家外科质量改进计划(ACS-NSQIP)2022参与者使用数据文件。我们的主要结果是术后死亡率。统计分析采用卡方检验,和多元回归分析。
    结果:关于多元回归分析,CID病史(OR:1.9;CI:1.5-2.5;p<0.01)和跌倒(OR:1.8,CI:1.4-2.3;p<0.01)均与较高的校正后死亡率独立相关.CID或跌倒的病史也是总体并发症的预测因子,主要并发症,并出院到护理机构。
    结论:在大型腹腔内手术之前,老年人的CID或跌倒史与术后死亡率和发病率的高风险相关。需要进一步的研究来确定这些因素的因果关系以及减轻相关不良后果风险的步骤。
    BACKGROUND: Both cognitive impairment/dementia (CID) and falls occur more commonly in older adults compared to younger patients. This study aims to analyze the association of a history of CID or falls with the postoperative outcomes of older adults undergoing major intraabdominal surgeries on a national level.
    METHODS: We retrospectively analyzed the American College of Surgeons-National Surgical Quality Improvement Program (ACS-NSQIP) 2022 Participant Use Data File. Our primary outcome was postoperative mortality. Statistical analysis was performed using Chi-square test, and multivariate regression analysis.
    RESULTS: On multivariable regression analyses, both a history of CID (OR: 1.9; CI: 1.5-2.5; p <0.01) and a fall (OR: 1.8, CI: 1.4 -2.3; p <0.01) were independently associated with higher adjusted odds of mortality. History of CID or falls was also a predictor of overall complications, major complications, and discharge to a care facility.
    CONCLUSIONS: A history of CID or falls in older adults prior to major intraabdominal surgeries is associated with a high risk of postoperative mortality and morbidity. Further studies are required to establish the causal relation of these factors and the steps to mitigate the risk of associated adverse outcomes.
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  • 文章类型: Journal Article
    目的:虽然现有文献报道了长期使用类固醇对手术伤口结局的不利影响,目前仍缺乏研究类固醇对下肢动脉搭桥手术后结局影响的数据.本研究旨在探讨长期使用类固醇对下肢动脉闭塞性疾病开放血运重建患者手术效果的影响。
    方法:使用2005年至2020年之间的美国外科医生协会国家外科质量改进计划(ACS-NSQIP)文件,所有接受主动脉或腹股沟下动脉旁路术治疗外周动脉疾病(PAD)的患者均通过当前程序术语(CPT)代码进行鉴定。使用χ2检验和独立t检验比较患者特征和30天结局,使用多变量逻辑回归分析研究了长期使用类固醇与伤口并发症的关系。
    结果:共有44,675例患者接受开放下肢血管重建术,其中1,807例患者使用慢性类固醇,42,868例患者未使用慢性类固醇。在多变量逻辑回归分析中,长期使用类固醇与较高的深部SSI发生率相关(OR1.37,95%CI1.03-1.83),任何SSI(OR1.22,95%CI1.04-1.43)和伤口裂开(OR1.42,95%CI1.03-1.96)。慢性类固醇使用者患败血症的几率也显著增加(OR1.56,95%CI1.19-2.04),肺炎(OR1.44,95%CI1.08-1.91),UTI(OR1.54,95%CI11.13-2.09),DVT(OR1.60,95%CI1.01-2.53),和30天再入院(OR1.30,95%CI1.12-1.50),与非慢性类固醇使用者相比,再次手术(OR1.17,95%CI1.01-1.37)和死亡率(OR1.33,95%CI1.01-1.76)。
    结论:这项研究证实,长期使用皮质类固醇与下肢动脉搭桥手术患者的手术部位感染(SSIs)风险较高有关。这些患者通常有各种潜在的健康问题,强调需要个性化的治疗和管理,以减少与类固醇相关的术后并发症并提高生存率。
    OBJECTIVE: While existing literature reports adverse effects of chronic steroid use on surgical wound outcomes, there remains lack of data exploring the effect of steroids on postoperative outcomes following lower extremity arterial bypass surgery. This study aims to explore the effect of chronic steroid use on surgical outcomes in patients undergoing open revascularization for lower extremity arterial occlusive disease.
    METHODS: Using the American College of Surgeons National Surgical Quality Improvement Program (ACS-NSQIP) files between 2005 and 2020, all patients receiving aortoiliac or infrainguinal arterial bypass for peripheral arterial disease (PAD) were identified by Current Procedural Terminology (CPT) codes. Patient characteristics and 30-day outcomes were compared using χ2 test and independent t-test, and association of chronic steroid use with wound complications was studied using multivariable logistic regression analysis.
    RESULTS: A total of 44,675 patients undergoing open lower extremity revascularization were identified, of which 1,807 patients were on chronic steroids and 42,868 patients were not on chronic steroids. On multivariable logistic regression analysis, being on chronic steroids was associated with higher rates of deep SSI (OR 1.37, 95% CI 1.03-1.83), any SSI (OR 1.22, 95% CI 1.04-1.43) and wound dehiscence (OR 1.42, 95% CI 1.03-1.96). Chronic steroid users also had significantly increased odds of developing sepsis (OR 1.56, 95% CI 1.19-2.04), pneumonia (OR 1.44, 95% CI 1.08-1.91), UTI (OR 1.54, 95% CI 11.13-2.09), DVT (OR 1.60, 95% CI 1.01-2.53), and 30-day readmission (OR 1.30, 95% CI 1.12-1.50), reoperation (OR 1.17, 95% CI 1.01-1.37) and mortality (OR 1.33, 95% CI 1.01-1.76) compared to non-chronic steroid users.
    CONCLUSIONS: This study confirms that chronic corticosteroid use is associated with higher risk of surgical site infections (SSIs) in patients undergoing lower extremity arterial bypass surgery. These patients typically have various underlying health issues, emphasizing the need for personalized treatment and management to reduce steroid-related postoperative complications and improve survival.
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  • 文章类型: Journal Article
    目的:虽然现有文献报道了下肢截肢(LEA)患者全身麻醉(GA)和区域麻醉(RA)的不同结果,尚未研究RA对充血性心力衰竭(CHF)患者的影响。这项研究旨在评估麻醉的选择是否在影响这一脆弱人群的结果中起作用。
    方法:使用2005-2022年间的美国外科医生协会国家外科质量改善计划(ACS-NSQIP)文件,确定了所有接受LEA的患者,并纳入CHF患者亚组。对分类变量采用χ2或Fischer精确检验,对连续变量采用独立t检验或Mann-WhitneyU检验,比较患者特征和30天结局。使用多变量逻辑回归分析研究麻醉方式与术后结果之间的关联。
    结果:共有5,831例患者(4,779例接受GA,1,052例接受RA),诊断为接受LEA的CHF。在多变量逻辑回归分析中,RA与较低的死亡率相关(aOR0.79,95%CI0.65-0.97),肺炎(aOR0.76,95%CI0.58-0.99),感染性休克(aOR0.64,95%CI0.47-0.88),术后输血(aOR0.82,95%CI0.70-0.97),30天再入院(aOR0.79,95%CI0.64-0.97)。
    结论:本研究表明,与GA相比,CHF患者的RA治疗LEA与降低发病率和死亡率相关。虽然需要进一步的研究来证实这种关联,在可行的情况下,至少应在接受LEA的CHF患者中考虑RA。
    OBJECTIVE: While existing literature reports variable results of general anesthesia (GA) and regional anesthesia (RA) in patients undergoing lower extremity amputation (LEA), the effect of RA on patients with congestive heart failure (CHF) has not been explored. This study aims to assess whether the choice of anesthesia plays a role in influencing outcomes within this vulnerable population.
    METHODS: Using the American College of Surgeons National Surgical Quality Improvement Program (ACS-NSQIP) files between 2005-2022, all patients receiving LEA were identified, and the subset of patients with CHF was included. Patient characteristics and 30-day outcomes were compared using χ2 or Fischer\'s exact test as appropriate for categorical variables and the independent t-test or Mann-Whitney U test as appropriate for continuous variables. The association between anesthesia modality and post-operative outcomes was studied using multivariable logistic regression analysis.
    RESULTS: A total of 5,831 patients (4,779 undergoing GA, 1,052 undergoing RA) with a diagnosis of CHF undergoing LEA were identified. On multivariable logistic regression analysis, RA was associated with lower mortality (aOR 0.79, 95% CI 0.65-0.97), pneumonia (aOR 0.76, 95% CI 0.58-0.99), septic shock (aOR 0.64, 95% CI 0.47-0.88), post-operative blood transfusion (aOR 0.82, 95% CI 0.70-0.97), and 30-day readmission (aOR 0.79, 95% CI 0.64-0.97).
    CONCLUSIONS: This study demonstrates that RA for LEA in patients with CHF is associated with decreased morbidity and mortality compared to GA. While further research is needed to confirm this association, RA should be at least considered in CHF patients undergoing LEA when feasible.
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  • 文章类型: Journal Article
    分化型甲状腺癌的最佳手术方式仍存在争议,关于前期甲状腺全切除术与初次肺叶切除术后分期完成甲状腺切除术的风险比较的争论。本研究旨在评估与这两种策略相关的并发症发生率,并使用四个队列的多维分析确定完成甲状腺切除术的最佳时机:机构系列(n=148),国家手术质量改进计划(NSQIP)数据库(n=39,992),TriNetX存储库(n>30,000),和综合文献综述(10项研究,n=6015)。机构数据显示,与完整甲状腺切除术(6.8%)相比,甲状腺全切除术(18.3%)的总并发症发生率更高,主要是由于暂时性低钙血症增加(10%vs.0%,p=0.004)。NSQIP分析显示甲状腺全切除术与暂时性低钙血症风险增加72%(p<0.001)和永久性低钙血症风险增加25%(p<0.001)相关。TriNetX数据证实了这些发现,并将肥胖和并发颈清扫术确定为并发症的危险因素。一项荟萃分析显示,甲状腺全切除术增加了短暂性(RR=1.63)和永久性(RR=1.23)低钙血症的发生率(p<0.001)。机构和TriNetX数据表明,与超过6个月的延迟相比,在初次肺叶切除术后1至6个月进行完整的甲状腺切除术可最大程度地减少永久性并发症的发生率。总之,分化型甲状腺癌,与分期完成甲状腺切除术相比,甲状腺全切除术发生短暂性和永久性低钙血症的风险更高.然而,在初次肺叶切除术后1~6个月内进行完整甲状腺切除术可以降低永久性并发症的风险.这些发现可以为分化型甲状腺癌患者提供个性化的手术决策。
    The optimal surgical approach for differentiated thyroid cancer remains controversial, with debate regarding the comparative risks of upfront total thyroidectomy versus staged completion thyroidectomy following the initial lobectomy. This study aimed to assess the complication rates associated with these two strategies and identify the optimal timing for completion thyroidectomy using a multi-dimensional analysis of four cohorts: an institutional series (n = 148), the National Surgical Quality Improvement Program (NSQIP) database (n = 39,992), the TriNetX repository (n > 30,000), and a pooled literature review (10 studies, n = 6015). Institutional data revealed higher overall complication rates with total thyroidectomy (18.3%) compared to completion thyroidectomy (6.8%), primarily due to increased temporary hypocalcemia (10% vs. 0%, p = 0.004). The NSQIP analysis demonstrated that total thyroidectomy was associated with a 72% increased risk of transient hypocalcemia (p < 0.001) and a 25% increased risk of permanent hypocalcemia (p < 0.001). TriNetX data confirmed these findings and identified obesity and concurrent neck dissection as risk factors for complications. A meta-analysis showed that total thyroidectomy increased the rates of transient (RR = 1.63) and permanent (RR = 1.23) hypocalcemia (p < 0.001). Institutional and TriNetX data suggested that performing completion thyroidectomy between 1 and 6 months after the initial lobectomy minimized permanent complication rates compared to delays beyond 6 months. In conclusion, for differentiated thyroid cancer, total thyroidectomy is associated with higher risks of transient and permanent hypocalcemia compared to staged completion thyroidectomy. However, performing completion thyroidectomy within 1-6 months of the initial lobectomy may mitigate the risk of permanent complications. These findings can inform personalized surgical decision-making for patients with differentiated thyroid cancer.
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    文章类型: Journal Article
    30天再入院是初次全关节置换术(TJA)后评估的重要质量指标,对医院绩效和报销有影响。医疗保险和医疗补助服务中心(CMS)和其他质量改进计划(即,国家手术质量改进计划[NSQIP])可能会在已发布的30天再入院率中造成不一致。这项研究的目的是使用两种不同的时间定义评估原发性TJA后30天的再入院率。
    通过电子病历(EMR)和机构NSQIP数据中的通用程序术语(CPT)代码识别了2015-2020年在单一学术机构接受原发性全髋关节和原发性全膝关节置换术的患者。确定了手术后30天内发生的再入院(与NSQIP中30天再入院的定义一致)和出院后30天内发生的再入院(与CMS中30天再入院的定义一致)。计算了30天的再入院率和不朽时期的再入院率。
    总共,包括4,202个主要TJA。平均住院时间(LOS)为1.79天。91%的患者出院回家。使用CMS定义的30天再入院率为3.1%(130/4,202)。使用NSQIP定义的30天再入院率为2.7%(113/4,202)。CMS定义捕获的八次再入院(6.1%)发生在不朽时期。
    CMS和NSQIP之间的主要TJA后30天再入院的时间定义差异导致30天再入院率不一致。证据等级:III。
    UNASSIGNED: 30-day readmission is an important quality metric evaluated following primary total joint arthroplasty (TJA) that has implications for hospital performance and reimbursement. Differences in how 30-day readmissions are defined between Centers for Medicare and Medicaid Services (CMS) and other quality improvement programs (i.e., National Surgical Quality Improvement Program [NSQIP]) may create discordance in published 30-day readmission rates. The purpose of this study was to evaluate 30-day readmission rates following primary TJA using two different temporal definitions.
    UNASSIGNED: Patients undergoing primary total hip and primary total knee arthroplasty at a single academic institution from 2015-2020 were identified via common procedural terminology (CPT) codes in the electronic medical record (EMR) and institutional NSQIP data. Readmissions that occurred within 30 days of surgery (consistent with definition of 30-day readmission in NSQIP) and readmissions that occurred within 30 days of hospital discharge (consistent with definition of 30-day readmission from CMS) were identified. Rates of 30-day readmission and the prevalence of readmission during immortal time were calculated.
    UNASSIGNED: In total, 4,202 primary TJA were included. The mean hospital length of stay (LOS) was 1.79 days. 91% of patients were discharged to home. 30-day readmission rate using the CMS definition was 3.1% (130/4,202). 30-day readmission rate using the NSQIP definition was 2.7% (113/4,202). Eight readmissions captured by the CMS definition (6.1%) occurred during immortal time.
    UNASSIGNED: Differences in temporal definitions of 30-day readmission following primary TJA between CMS and NSQIP results in discordant rates of 30-day readmission. Level of Evidence: III.
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  • 文章类型: Journal Article
    作为状态,区域,国家登记册迅速扩大,本研究的目的是评估2012年至2022年期间,美国髋关节和膝关节外科医生协会在讲台和海报上接受的注册摘要的频率.
    在过去11年中对最终计划和海报电子收藏进行了审查。两名审阅者评估了每个摘要,以确定他们是否使用了大型数据集以及每个注册表的位置。如果研究使用机构登记册,则被排除在外。审稿人还确定了最常用的登记册,以确定其使用在这一时间范围内的波动情况。
    共审查并包括3354篇摘要。其中,577份摘要利用了从骨科注册获得的数据(17.2%):其中450份是海报展示(占总海报接受度的16.5%),和127个是讲台演讲(接受讲台的20.5%)。国家外科质量改进计划(NSQIP)是最常用的数据集,有118份(20.5%)摘要。值得注意的是,NSQIP的使用在2018年至2020年期间达到顶峰,此后一直呈缓慢下降趋势。另一方面,自2019年以来,美国关节置换登记处(AJRR)和PearlDiver登记处的使用急剧增加,2019年仅选择了6份摘要,2022年选择了28份摘要(10份AJRR[3个讲台]和18份PearlDiver[6个讲台])。登记册数据的比例有所增加,注册摘要在2022年达到峰值,因为24%的海报和37%的讲台使用了来自大型注册数据集的数据(P<.001)。
    在美国髋关节和膝关节外科医生协会年会上,利用注册数据进行讲台和海报展示的研究数量显着增加。虽然NSQIP是使用最多的,在过去的3年中,其使用量稳步下降,而AJRR和PearlDiver的使用量有所增加。在对研究结果做出结论之前,个人应了解每个注册表的优缺点。
    四级。
    UNASSIGNED: As state, regional, and national registries have rapidly expanded, the goal of this study is to assess the frequency of registry abstracts accepted for both podium and poster presentations at the American Association of Hip and Knee Surgeons between 2012 and 2022.
    UNASSIGNED: Final programs and poster e-collections were examined over the past 11 years. Two reviewers evaluated each abstract to determine if they utilized large datasets and the location of each registry. Studies were excluded if they used institutional registries. Reviewers also identified the most frequently utilized registries to determine how their use has fluctuated over this time frame.
    UNASSIGNED: A total of 3354 abstracts were reviewed and included. Of those, 577 abstracts utilized data obtained from orthopaedic registries (17.2%): 450 of which were poster presentations (16.5% of total poster acceptances), and 127 were podium presentations (20.5% of accepted podiums). The National Surgical Quality Improvement Program (NSQIP) was the most frequent dataset utilized, with 118 (20.5%) abstracts. Of note, NSQIP\'s use peaked between 2018 and 2020 and has since slowly trended downward. On the other hand, use of both American Joint Replacement Registry (AJRR) and PearlDiver registry have drastically increased since 2019, with only 6 abstracts chosen in 2019 and 28 abstracts in 2022 (10 AJRR [3 podiums] and 18 PearlDiver [6 podiums]). The proportion of registry data has increased, with the registry abstracts peaking in 2022 as 24% of posters and 37% of podium utilized data from large registry data sets (P < .001).
    UNASSIGNED: There has been a significant increase in the number of studies utilizing registry data for both podium and poster presentations at the American Association of Hip and Knee Surgeons annual meeting. While NSQIP was the most utilized, its use has steadily declined while AJRR and PearlDiver use have increased over the past 3 years. Individuals should understand the strengths and weaknesses of each registry before making conclusions on study results.
    UNASSIGNED: Level IV.
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  • 文章类型: Journal Article
    背景:营养不良通常与手术后并发症增加和预后恶化有关。这项研究的目的是确定使用老年营养风险指数(GNRI)确定的营养不良状况是否可以作为前路颈椎间盘切除术和融合术(ACDF)患者并发症的独立危险因素。
    方法:从2011年至2016年,美国外科医生学会国家外科质量改善计划数据库查询了接受ACDF的年龄≥65岁的患者。根据GNRI将患者分为3组:>98为正常营养状况,92-98人中度营养不良,<92人严重营养不良。根据人口统计的协变量调整的多变量逻辑回归模型,合并症,和手术指标用于评估GNRI作为术后结局的独立危险因素。
    结果:分析了3,148例接受ACDF的患者,其中78.9%的人营养正常,16.1%为中度营养不良,5.0%的患者严重营养不良。在多变量分析中,研究发现,中度和重度营养不良是任何并发症的独立危险因素。肺部并发症,肺炎,计划外插管,住院时间>6天(所有,p<0.05)。此外,中度营养不良是呼吸机>48小时和30日再入院失败的危险因素.严重营养不良是感染性休克和非家庭出院的独立危险因素。
    结论:在ACDF后的老年患者中,使用GNRI确定的营养不良是30天并发症的独立危险因素,再入院,延长住院时间,和非家庭放电。
    BACKGROUND: Malnutrition frequently is associated with increased complications and worse outcomes after surgery. The purpose of this study was to determine whether malnutrition status determined using the Geriatric Nutritional Risk Index (GNRI) can serve as an independent risk factor for complications in patients undergoing anterior cervical discectomy and fusion (ACDF).
    METHODS: The American College of Surgeons National Surgical Quality Improvement Program database was queried from 2011 to 2016 for patients age ≥65 years who underwent ACDF. Patients were categorized into 3 groups based on the GNRI: >98, normal nutritional status; 92-98, moderately malnourished; and <92, severely malnourished. Multivariate logistic regression models adjusted for covariates of demographics, comorbidities, and operative metrics were used to evaluate GNRI as an independent risk factor for postoperative outcomes.
    RESULTS: A total of 3148 patients who underwent ACDF were analyzed, of whom 78.9% had normal nutrition, 16.1% were moderately malnourished, and 5.0% patients were severely malnourished. On multivariate analysis, moderate and severe malnutrition were found to be independent risk factors for any complication, pulmonary complications, pneumonia, unplanned intubation, and hospital length of stay >6 days (P < 0.05 for all). In addition, moderate malnutrition was a risk factor for failure to wean from ventilation for >48 hours and 30-day readmission. Severe malnutrition was an independent risk factor for septic shock and nonhome discharge.
    CONCLUSIONS: In elderly patients after ACDF, malnutrition determined using GNRI is an independent risk factor for 30-day complications, readmissions, prolonged hospital length of stay, and nonhome discharge.
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  • 文章类型: Journal Article
    目的:股骨远端骨折仍然是老年患者发病率和死亡率的重要原因。缺乏调查老年患者股骨远端c术后短期预后的大型人群研究。这项研究的目的是评估老年人群股骨远端切开复位内固定术(ORIF)后各种短期结局的发生率和危险因素。
    方法:美国外科医生学会国家外科质量改进计划(NSQIP)数据库用于识别2015年1月1日至2020年12月31日之间60岁以上患者的所有原发性股骨远端ORIF病例,使用当前程序术语(CPT)代码27511、27513和27514。人口统计,medical,并提取所有患者的手术变量。根据各种人口统计学和医学合并症变量,使用倾向评分匹配来匹配两个年龄组的病例。在匹配之前和之后,比较了60-79岁和80岁以上组之间的几个30天结果指标。随后的多变量逻辑回归用于确定匹配队列中30天结局指标的独立危险因素。
    结果:最终队列共纳入2913例患者:60-79岁组1711例患者,80+岁组1202例患者。大多数患者为女性(n=2385;81.9%)。在匹配之前,老年组30天死亡率较高(1.9%vs.6.2%),再入院(3.7%与9.7%,p=0.024),和非家庭放电(74.3%vs.89.5%,p<0.001)。此外,老年组需要输血的失血率较高(30.9%vs.42.3%,p<0.001)和医疗并发症(10.4%vs.16.4%,p<0.001),包括心肌梗死(0.7%vs.2.7%,p<0.001),肺炎(2.7%vs.4.6%,p=0.008),和尿路感染(4.1%vs.6.1%,p=0.0188)。匹配后,老年组的死亡率一直较高,非家庭放电,失血需要输血,和心肌梗塞。确定了30天发病率和死亡率的各种独立危险因素,包括美国麻醉医师协会(ASA)分类,身体质量指数(BMI)状态,手术持续时间,和某些医疗合并症。
    结论:老年患者接受股骨远端ORIF的30天发病和死亡风险显著。匹配后,特别是八十岁和老年患者的死亡风险增加,非家庭放电,与60-79岁患者相比,手术并发症。多重因素,例如BMI状态,ASA分类,手术时间,和某些医疗合并症,与差的30天结果独立相关。
    OBJECTIVE: Distal femur fractures remain a significant cause of morbidity and mortality for elderly patients. There is a lack of large population studies investigating short-term outcomes after distal femur c in elderly patients. The purpose of this study is to assess the incidence of and risk factors for various short-term outcomes after distal femur open reduction internal fixation (ORIF) in the geriatric population.
    METHODS: The American College of Surgeons\' National Surgical Quality Improvement Program (NSQIP) database was used to identify all primary distal femur ORIF cases in patients 60+ years old between January 1, 2015 and December 31, 2020 using Current Procedural Terminology (CPT) codes 27511, 27513, and 27514. Demographic, medical, and surgical variables were extracted for all patients. Propensity score matching was used to match cases in the two age groups based on various demographic and medical comorbidity variables. Several 30-day outcome measures were compared between the 60-79-year-old and 80+-year-old groups both before and after matching. Subsequent multivariate logistic regression was used to identify independent risk factors for 30-day outcome measures in the matched cohort.
    RESULTS: A total of 2913 patients were included in the final cohort: 1711 patients in the 60-79-year-old group and 1202 patients in the 80+-year-old group. Most patients were female (n = 2385; 81.9%). Prior to matching, the older group had a higher incidence of 30-day mortality (1.9% vs. 6.2%), readmission (3.7% vs. 9.7%, p = 0.024), and non-home discharge (74.3% vs. 89.5%, p < 0.001). Additionally, the older group had a higher rate of blood loss requiring transfusion (30.9% vs. 42.3%, p < 0.001) and medical complications (10.4% vs. 16.4%, p < 0.001), including myocardial infarction (0.7% vs. 2.7%, p < 0.001), pneumonia (2.7% vs. 4.6%, p = 0.008), and urinary tract infection (4.1% vs. 6.1%, p = 0.0188). After matching, the older group consistently had a higher incidence of mortality, non-home-discharge, blood loss requiring transfusion, and myocardial infarction. Various independent risk factors were identified for 30-day morbidity and mortality, including American Society of Anesthesiologists (ASA) classification, body mass index (BMI) status, operative duration, and certain medical comorbidities.
    CONCLUSIONS: Geriatric patients undergoing distal femur ORIF are at significant risk for 30-day morbidity and mortality. After matching, octogenarians and older patients specifically are at increased risk for mortality, non-home discharge, and surgical complications compared to patients aged 60-79 years old. Multiple factors, such as BMI status, ASA classification, operative time, and certain medical comorbidities, are independently associated with poor 30-day outcomes.
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