Mycotic

霉菌
  • 文章类型: Journal Article
    感染性天然动脉瘤和炎性主动脉瘤是罕见的,但在紧急情况下,血管外科医生会看到病态的病变。介绍并不总是清晰的,在采取管理策略之前,必须进行全面的检查。治疗是多学科的,根据检查结果为每个病例量身定制。用计算机断层扫描成像,磁共振,或氟脱氧葡萄糖-正电子发射断层扫描有助于诊断和监测对治疗的反应。传统上进行开放式手术以进行明确的管理。在选择结果可接受的病例中,血管内手术可以提供替代治疗。这两种技术都没有被证明优于其他技术。医生应该考虑病人的解剖结构,合并症,预期寿命,和选择方法之前的护理目标。长期的药物治疗,在感染性动脉瘤的情况下使用抗生素,在炎性动脉瘤的情况下使用免疫抑制剂,通常是必需的,应该与传染病专家和风湿病学家合作管理。
    Infective native arterial aneurysms and inflammatory aortic aneurysms are rare but morbid pathologies seen by vascular surgeons in the emergency setting. Presentation is not always clear, and a full workup must be obtained before adopting a management strategy. Treatment is multidisciplinary and is tailored to every case based on workup findings. Imaging with computed tomography, magnetic resonance, or with fluorodeoxyglucose-positron emission tomography aids in diagnosis and in monitoring response to treatment. Open surgery is traditionally performed for definitive management. Endovascular surgery may offer an alternative treatment in select cases with acceptable outcomes. Neither technique has been proven to be superior to the other. Physicians should consider patient\'s anatomy, comorbidities, life expectancy, and goals of care before selecting an approach. Long-term pharmacological treatment, with antibiotics in case of infective aneurysms and immunosuppressants in case of inflammatory aneurysms, is usually required and should be managed in collaboration with infectious disease specialists and rheumatologists.
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  • 文章类型: Case Reports
    霉菌性颈动脉假性动脉瘤对外科医生来说是一个挑战。它们是罕见的并且与高死亡率和发病率相关。
    我们报告了一例61岁男性颈动脉分叉部的真菌性假性动脉瘤。这个案子是分阶段处理的,从使用支架移植物的初始血管内控制开始,然后使用大隐静脉移植进行开放动脉重建。
    患者出院,颈动脉通畅,无感染或出血迹象。在1个月时进行计算机断层扫描,6个月,1年后证实移植物通畅良好,无脑缺血成像。
    颅外颈动脉的真菌性假性动脉瘤很少见,应始终进行手术治疗。这种疾病,尽管它很罕见,需要早期发现和治疗,以避免致命的结果。提出了一种混合分阶段的方法,与一期手术相比,以避免破裂和改善临床结果。这种方法涉及使用支架移植物结合抗生素治疗作为桥接治疗,直到可以进行明确的手术,以便使用自体移植物进行动脉重建。
    UNASSIGNED: Mycotic carotid pseudoaneurysms represent a challenge for surgeons. They are rare and associated with high mortality and morbidity.
    UNASSIGNED: We reported a case of a 61-year-old man with a mycotic pseudoaneurysm of carotid bifurcation. The case was managed by a staged procedure, starting with initial endovascular control using a stent graft, followed by open arterial reconstruction using a saphenous vein graft.
    UNASSIGNED: The patient was discharged home with a patent carotid artery and no sign of infection or bleeding. A computed tomography scan performed at 1 month, 6 months, and 1 year later confirmed good patency of the graft without imaging of cerebral ischemia.
    UNASSIGNED: Mycotic pseudoaneurysms of the extracranial carotid artery are rare and should always be treated surgically. This disease, despite its rarity, requires early detection and treatment to avoid fatal outcomes. A hybrid staged approach is suggested, compared to one-staged surgery, to avoid rupture and improve clinical outcomes. This approach involves using a stent graft combined with antibiotic therapy as bridge treatment until definitive surgery can be performed to enable arterial reconstruction with an autologous graft.
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  • 文章类型: Journal Article
    感染或霉菌性主动脉瘤(MAAs)是一种罕见的动脉瘤。由于破裂的风险很高,MAAs是危及生命的疾病。早期诊断和治疗是必要的,然而MAAs通常是偶然发现的。我们报告了10例MAAs患者,他们在宏观上,在所有病例中均见主动脉内壁大小相似的病变.当在主动脉瘤的开放手术修复期间看到主动脉内壁上的硬币大小的病变时,外科医生应该考虑感染原因。应收集微生物组织样本,应开始额外的靶向抗生素治疗.
    Infected or mycotic aortic aneurysms (MAAs) are a rare type of aneurysms. Due to the high risk of rupture, MAAs are life-threatening conditions. Early diagnosis and treatment are necessary, yet MAAs are usually found coincidentally. We report 10 patients with MAAs in whom macroscopically, similar coined-sized lesions of the inner aortic wall were seen in all cases. When a coin-sized lesion in the inner aortic wall is seen during open surgical repair of an aortic aneurysm, the surgeon should consider an infectious cause. Microbiological tissue samples should be collected, and additional targeted antibiotic therapy should be started.
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  • 文章类型: Case Reports
    气道阻塞需要紧急干预。在处理右头臂动脉霉菌性假性动脉瘤时,破裂和大出血的风险增加了管理的紧迫性.此外,气管压迫在气道管理过程中存在困难。本报告重点介绍了手术过程中遇到的气道和麻醉挑战,并强调了量身定制的干预措施对最佳患者护理的重要性。我们描述了一名38岁男性患者的临床病例,该患者出现了与气管压迫相关的大量复发性右头臂动脉假性动脉瘤。由于假性动脉瘤扩大和进行性呼吸窘迫,患者需要紧急手术干预。清醒光纤插管是不可行的。在插管和通气失败的情况下,体外循环保持待命,或循环崩溃。使用视频喉镜成功进行了气管内插管。假性动脉瘤手术修复成功后,病人被转移到ICU,术后48小时拔管,使用甲基强的松龙治疗视频喉镜检查期间发现的水肿性会厌褶皱。总的来说,这个案例强调了早期诊断的重要性,及时手术干预,以及有效的团队合作来管理罕见的和可能危及生命的疾病,如霉菌性假性动脉瘤。它还强调了麻醉师在提供最佳围手术期护理方面的关键作用,确保血液动力学稳定性,管理气道挑战,并促进成功的手术结果。在我们的工作中,我们还提供了报告的类似病例的摘要。
    Airway obstruction requires urgent intervention. When dealing with the right brachiocephalic artery mycotic pseudoaneurysms, the risk of rupture and massive hemorrhage adds greater urgency to the management. Furthermore, tracheal compression presents difficulties during airway management. This report highlights the airway and anesthetic challenges encountered during the procedure and emphasizes the importance of tailored intervention for optimal patient care. We describe the clinical case of a 38-year-old male patient who presented with a large recurrent right brachiocephalic artery pseudoaneurysm associated with tracheal compression. The patient required urgent surgical intervention due to the pseudoaneurysm\'s enlargement and progressive respiratory distress. Awake fiber-optic intubation was not feasible. A cardiopulmonary bypass was kept on standby in the event of failed intubation and ventilation, or circulatory collapse. Endotracheal intubation was performed successfully using a video-laryngoscopy. After successful surgical repair of the pseudoaneurysm, the patient was transferred to ICU where he was extubated 48 hours post-surgery, following treatment with methylprednisolone for edematous aryepiglottic folds identified during video-laryngoscopy. Overall, this case emphasizes the importance of early diagnosis, prompt surgical intervention, and effective teamwork in managing rare and potentially life-threatening conditions like mycotic pseudoaneurysms. It also highlights the critical role of anesthesiologists in providing optimal perioperative care, ensuring hemodynamic stability, managing airway challenges, and facilitating successful surgical outcomes. In our work, we also provide a summary of the reported similar cases.
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  • 文章类型: Case Reports
    锁骨下动脉霉菌性动脉瘤的手术修复取决于动脉瘤的特异性特征,解剖暴露可能需要胸骨切开术。开胸手术,或者锁骨上切口.或者,可以使用正中锁骨切除术。我们在一名患有多种合并症的23岁男子中成功地进行了锁骨下动脉到腋下动脉的旁路手术,并进行了锁骨切除术。术后多普勒超声显示左腋下动脉未闭,可触及左桡动脉,患者表现出完整的左肩活动范围,没有任何明显的畸形。此病例表明,锁骨下动脉霉菌性动脉瘤患者的中位锁骨切除术可以产生令人满意的结果。
    Surgical repair of a subclavian artery mycotic aneurysm is dependent on aneurysm-specific characteristics and anatomic exposures could require sternotomy, thoracotomy, or supraclavicular incisions. Alternatively, a median claviculectomy can be used. We successfully performed a subclavian artery to axillary artery bypass with median claviculectomy in a 23-year-old man with multiple comorbidities. Postoperative Doppler ultrasound showed a patent left axillary artery with a palpable left radial artery, and the patient demonstrated full left shoulder range of motion without any significant deformities. This case suggests that a median claviculectomy can produce satisfactory outcomes in patients with subclavian artery mycotic aneurysms.
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  • 文章类型: Case Reports
    Mycotic pseudoaneurysm of the ascending aorta is extremely uncommon, particularly in children with no prior cardiac surgery or trauma. We report a rare case of a mycotic pseudoaneurysm of the ascending aorta in a 2-year-old girl with no history of cardiac surgery. Investigations revealed a methicillin-resistant Staphylococcus aureus infection and significant pericardial effusion in the child who presented with persistent fever and altered mental state. Cardiac ultrasound revealed a disruption in the aortic wall and a tumor-like structure. Contrast-enhanced computed tomography confirmed an ascending aortic pseudoaneurysm with thrombus. The child underwent successful surgical treatment without implants. This case emphasizes the diagnostic significance of imaging, particularly the advantages of ultrasound in pediatric settings, and the need for timely and accurate diagnosis using appropriate imaging modalities in children.
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  • 文章类型: Case Reports
    近年来,真菌性主动脉瘤已越来越多地通过血管内手段成功治疗。引入定制的开窗和分支装置,平行移植技术,原位开窗术也使足弓病变的全血管内治疗成为可能。我们描述了使用静脉动脉体外膜氧合进行原位激光开窗术的真菌弓动脉瘤的全血管内修复,以保持流向重要器官的流量。
    In recent years, mycotic aortic aneurysms have been increasingly treated successfully by endovascular means. The introduction of custom-made fenestrated and branched devices, parallel graft techniques, and in situ fenestration has enabled total endovascular treatment also for arch pathologies. We describe a total endovascular repair of a mycotic arch aneurysm with in situ laser fenestration using venoarterial extracorporeal membrane oxygenation to preserve flow to vital organs.
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  • 文章类型: Case Reports
    在难以治疗的鼻旁窦疾病中,应始终考虑真菌感染。蝶骨真菌球的特征在于窦腔中存在致密的真菌团,而不侵入周围组织。此案例强调了准确术语和管理的重要性,并强调了诸如夏威夷Drechslera之类的稀有病原体的参与。诊断通常基于成像研究和术中发现。病原体的准确鉴定至关重要。鼻旁窦真菌感染,包括真菌球,可以在诊断和治疗中提出挑战。D.夏威夷,虽然不常见,会导致潜在的威胁生命的感染.
    我们介绍了一名26岁的非HIV男性患者,他有鼻部症状和轻度头痛。患者接受了内窥镜探查,发现软,带黄油稠度的灰色病变。实现了总切除,病变被确定为由夏威夷D.引起;因此,给予静脉抗真菌治疗。
    内镜手术仍然是疾病控制的首选方法。考虑替代治疗和探索新方法对于在神经外科实践中管理复杂的病理至关重要。
    UNASSIGNED: Fungal infections should always be considered in difficult-to-treat paranasal sinus conditions. Sphenoid fungal balls are characterized by the presence of dense fungal masses in the sinus cavity without invasion of surrounding tissues. This case emphasizes the importance of accurate terminology and management and also highlights the involvement of rare pathogens such as Drechslera hawaiiensis. Diagnosis is typically based on imaging studies and intraoperative findings. Accurate identification of the pathogen is crucial. Fungal infections of the paranasal sinuses, including fungus balls, can present challenges in diagnosis and treatment. D. hawaiiensis, although infrequent, can cause potential life-threatening infections.
    UNASSIGNED: We present a 26-year-old non-HIV male patient who presented with nasal symptoms and mild headaches. The patient underwent an endoscopic exploration that revealed a soft, grayish lesion with a buttery consistency. Gross total resection was achieved and the lesion was identified as being caused by D. hawaiiensis; thus, intravenous antifungal treatment was given.
    UNASSIGNED: Endoscopic surgery remains the preferred approach for disease control. Considering alternative treatments and exploring novel approaches are essential in managing complex pathologies in neurosurgical practice.
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  • 文章类型: Journal Article
    霉菌性主动脉瘤破裂是罕见且严重的疾病,需要及时治疗。主动脉切除和原位或解剖重建的开放手术是标准治疗方法。本技术说明的目的是报告使用现成的定制设备(为另一名患者创建)进行紧急血管内治疗,使用心包补片和新开窗进行后表修改。
    在基于中心线的工作站上进行术前测量时,除左肾动脉外,近端和远端着陆区的主动脉直径以及目标血管位置与定制设备(CMD)的移植计划的测量值相匹配。为了解决当前患者的解剖结构,用心包补片封闭不合适的开窗,并为各自的目标血管创建新的开窗(原开窗后1:15小时以上)。术后计算机断层扫描血管造影(CTA)扫描显示动脉瘤完全排除,灌注靶血管,也没有内漏。在基于耐药性的抗生素治疗下,患者无症状,术后血液样本中的感染参数正常。
    在经验丰富的血管内主动脉外科医生的手中,定制装置的修改在这种紧急情况下是一种快速可行的技术。长期随访必须确认这种新技术的耐久性和可靠性。
    所描述的定制内移植物的修饰技术可以为紧急复杂的腹主动脉病变提供替代的血管内治疗选择。与目前可用的治疗方式相比,比如医生改良的内移植物,现成的分支设备,平行移植物和原位开窗,它可以节省大量的时间,并在破裂的情况下提供合理的密封。该技术为经验丰富的血管内医师的医疗设备提供了宝贵的补充。
    UNASSIGNED: Ruptured mycotic pararenal aortic aneurysms are rare and serious condition that requires prompt treatment. Open surgery with aortic resection and in-situ or extra-anatomic reconstruction is the standard treatment. The aim of this technical note is to report urgent endovascular treatment using a readily available custom-made device (created for another patient), with a back-table modification using pericardium patch and a new fenestration.
    UNASSIGNED: In preoperative measurements on centerline-based workstation, aortic diameter in proximal and distal landing zone and target vessel position matched the measurements of graft plan of custom-made device (CMD) besides left renal artery. To address current patient`s anatomy, closure of the nonsuitable fenestration with pericardial patch and creation of new fenestration (1 cm above and 1:15 hours posterior to original fenestration) for the respective target vessel have been performed. Postoperative computed tomography angiography (CTA) scan showed complete exclusion of aneurysm, perfused target vessels, and no endoleak. Under resistance-based antibiotic therapy, the patient was asymptomatic and showed normal infection parameters in blood samples postoperatively.
    UNASSIGNED: In the hands of an experienced endovascular aortic surgeon modification of a custom-made device is a quick and feasible technique in this emergency situation. Long-term follow-up must confirm the durability and reliability of this new technique.
    UNASSIGNED: The described technique of modification of a custom-made endograft can provide an alternative endovascular treatment option for urgent complex abdominal aortic pathologies. Compared to the current available treatment modalities, like physician modified endografts, off-the-shelf branched devices, parallel grafts and in-situ fenestration, it can save considerable time and provides reasonable sealing in ruptured cases. The technique offers a valuable add-on to the armamentarium of experienced endovascular physicians.
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  • 文章类型: Case Reports
    我们介绍了一例77岁的中风患者。随后,她感到不适,被发现患有自发性感染性天然颈动脉假性动脉瘤。患者按照她的意愿得到了保守的管理。尽管这种临床诊断很少见,临床医生应了解该实体的病理生理学以及有关管理的现有文献.
    We present a case of a 77-year-old patient who presented with a stroke. She subsequently became unwell and was found to have a spontaneous infective native carotid artery pseudoaneurysm. The patient was managed conservatively as per her wishes. Despite the rarity of this clinical diagnosis, clinicians should be aware of the pathophysiology of this entity and the available literature on management.
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