■kansasii分枝杆菌(M.kansasii)是一种高度流行的非结核细菌,通过气溶胶从水和土壤资源转移到呼吸系统。KansasiiM.是引起NTM肺病的主要物种之一。
■WebofScience,Scopus,系统探索了PubMed数据库。回顾了1971年至2023年11月的相关文章。“纳入标准”包括堪萨斯分枝杆菌感染的患者,治疗随访,和治疗结果。“排除标准”是来自动物的临床样本,环境样本,和其他实验室调查。
■40项研究,包括1201名患者,是通过数据库搜索获得的。使用不同研究中使用的治疗方案,KansasiiM.感染患者的疗程为1周至118个月.在这项研究中,在不同的治疗方案中,用于Kansasii肺部感染的抗生素如下:利福平,乙胺丁醇,异烟肼,克拉霉素,链霉素,还有吡嗪酰胺.三四种药物的抗生素组合,包括利福平,乙胺丁醇,异烟肼加用或不加用链霉素或吡嗪酰胺治疗效果最好。
■初始治疗涉及利福平,乙胺丁醇,异烟肼,还有吡哆醇,根据美国胸科学会(ATS)和美国传染病学会(IDSA)的指南。了解治疗计划及其结果对于管理和确定最有效的治疗方法至关重要。
UNASSIGNED: Mycobacterium kansasii (M. kansasii) is a non-tuberculosis bacterium with a highly prevalent that is transferred by aerosols from water and soil resources to the respiratory system. M. kansasii is one of the main species responsible for NTM pulmonary disease.
UNASSIGNED: Web of Science, Scopus, and PubMed databases were systematically explored. Relevant articles from 1971 to November 2023 were reviewed. \"The inclusion criteria\" included patients with M. kansasii infection, treatment follow-up, and treatment outcomes. \"The exclusion criteria\" were clinical samples from animals, environmental samples, and other laboratory investigations.
UNASSIGNED: 40 studies, including 1201 patients, were obtained through database search. Using the therapeutic regimens used in different studies, the therapy course for patients with M. kansasii infection ranged from 1 week to 118 months. In this study, the antibiotics prescribed in different treatment regimens for M. kansasii pulmonary infection were as follows: Rifampin, Ethambutol, Isoniazid, Clarithromycin, Streptomycin, and Pyrazinamide. Antibiotic combinations of three or four medicines, including rifampin, ethambutol, and isoniazid with or without streptomycin or pyrazinamide had the most therapeutic effect.
UNASSIGNED: The initial treatment involves rifampin, ethambutol, isoniazid, and pyridoxine, per the guidelines from the American Thoracic Society (ATS) and the Infectious Diseases Society of America (IDSA). Understanding the treatment plan and its outcomes is crucial for managing and determining the most effective therapy approach.