Multi-country study

多国研究
  • 文章类型: Journal Article
    最佳能源组合是可持续发展的必要条件。然而,全球能源结构次优地由化石主导,这危及能源安全并威胁实现可持续发展。理解能源系列的趋同可以帮助过渡到最佳能源组合和可持续发展。因此,近年来,关于几个能量序列收敛性的研究越来越受到重视。本研究通过对79个中下层小组的几个维度研究能源多样化的趋同,扩展了自然资源和环境系列趋同的文献中的这一重要生态位,中高级,和高收入国家。从现有的研究出发,这项研究采用了一种新颖的方法,允许通过平滑断裂的傅立叶近似突然或平滑的变化,同时包括因子结构以测试相对能量多样化系列中单位根的存在。结果提供了在大多数考虑的国家中能源多样化系列趋同的证据,90%的样本表现出收敛性。进行了分类国家分析,结果表明,93%的中低收入国家正在趋同,而95%的中高收入国家和87%的高收入国家正在趋同。还讨论了调查结果的政策含义。
    An optimal energy mix is a sine qua non for sustainable development. However, the global energy mix is sub-optimally dominated by fossils which endangers energy security and threatens the attainment of sustainable development. Understanding the convergence of energy series can assist the transition path to optimal energy mix and sustainable development. Thus, research on the convergence of several energy series has gained prominence in recent years. This study extends this important niche in the literature on the convergence of natural resources and environmental series by examining the convergence in energy diversification along several dimensions for a panel of 79 lower-middle, higher-middle, and high-income countries. As a departure from the existing studies, the study employs a novel methodology that allows abrupt or smooth changes through the Fourier approximation of smooth breaks, while including factor structures to test for the presence of unit roots in the relative energy diversification series. The results provide evidence of convergence of the energy diversification series in the majority of the considered countries, with 90% of the sample demonstrating convergence. A disaggregated country analysis was conducted and the findings show that 93% of the lower-middle-income countries are converging, while 95% of the upper-middle-income countries and 87% of the high-income countries are converging. Policy implications of the findings are also discussed.
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  • 文章类型: Journal Article
    背景:在COVID-19大流行的背景下,药剂师,尽管他们做出了重要贡献,面临重大挑战,影响了他们的心理健康,可能导致创伤后应激症状(PTSS)的发展。这项研究的目的是调查工作相关的疲劳在药剂师的韧性与他们在COVID-19大流行期间经历PTSS的可能性之间的关系中作为潜在调节者的作用。
    方法:于2021年1月至12月在包括巴西在内的八个国家在线进行了横断面调查,黎巴嫩,尼日利亚,巴基斯坦,波兰,塞尔维亚,突尼斯。调解分析是使用PROCESSMACRO(SPSS附加组件)v3.4模型1进行的,将工作疲劳作为弹性与PTSS之间关联的调节剂。
    结果:本研究共招募了442名药剂师(平均年龄为33.91±10.36岁),其中59.5%为女性。结果在全国范围内进行了调整,性别,与COVID-19接触,工作患者,强制性工作时间,自愿工作时间,年龄,家庭拥挤指数和从事COVID-19的月份数。物理的相互作用弹性(β=0.02;p=0.029),精神(Beta=0.02;p=.040)和情绪(Beta=0.03;p=.008)工作疲劳与PTSS显着相关;对于具有低至中等水平的药剂师(Beta=-0.33;p<.001和Beta=-0.21;p=.001),精神(Beta=-0.29;p<.001和Beta=-0.18;p=.006)和情绪(Beta=-0.31;p<.001和Beta=-0.17;p=.008)工作疲劳,较高的弹性与较低的PTSS水平显著相关。然而,对于具有高度身体/心理/情绪工作疲劳的药剂师,韧性与PTSS之间的相关性无统计学意义.
    结论:这项研究强调了与工作相关的疲劳之间的复杂关系,弹性,和药剂师的PTSS。它强调需要解决药剂师在危机期间的心理健康与工作相关的疲劳,为量身定制的支持和干预提供见解。
    BACKGROUND: In the context of the COVID-19 pandemic, pharmacists, despite their vital contributions, have faced significant challenges that have impacted their mental well-being, potentially leading to the development of Post-Traumatic Stress symptoms (PTSS). The aim of this study was to investigate the role of work-related fatigue as a potential moderator in the relationship between pharmacists\' resilience and their likelihood of experiencing PTSS during the COVID-19 pandemic.
    METHODS: A cross-sectional survey was conducted online in eight countries from January to December 2021, including Brazil, Lebanon, Nigeria, Pakistan, Poland, Serbia, and Tunisia. The mediation analysis was conducted using PROCESS MACRO (an SPSS add-on) v3.4 model 1, taking work fatigue as a moderator in the association between resilience and PTSS.
    RESULTS: A total of 442 pharmacists were enrolled in this study (mean age = 33.91 ± 10.36 years) with 59.5% of them being females. The results were adjusted over country, gender, working in contact with COVID-19, working patients, working mandatory hours, working voluntary hours, age, household crowding index and number of months engaged in COVID-19. The interactions resilience by physical (Beta = 0.02; p = .029), mental (Beta = 0.02; p = .040) and emotional (Beta = 0.03; p = .008) work fatigue were significantly associated with PTSS; for pharmacists with low to moderate levels of physical (Beta = - 0.33; p < .001 and Beta = - 0.21; p = .001), mental (Beta = - 0.29; p < .001 and Beta = - 0.18; p = .006) and emotional (Beta = - 0.31; p < .001 and Beta = - 0.17; p = .008) work fatigue, higher resilience was significantly related to lower PTSS levels. However, for pharmacists with high levels of physical/mental/emotional work fatigue, the association between resilience and PTSS became non-significant.
    CONCLUSIONS: This study highlights the complex relationship between work-related fatigue, resilience, and PTSS in pharmacists. It emphasizes the need to address work-related fatigue for pharmacists\' psychological well-being during crises, offering insights for tailored support and interventions.
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  • 文章类型: Journal Article
    目的:需要新的流行病学方法来减少超低频磁场(ELF-MF)与儿童白血病之间关联的科学不确定性。虽然以前的研究大多集中在电力线上,变压器暴露研究试图通过一项多国研究来评估这种关联,研究对象是居住在内置变压器的建筑物中的儿童.内置变压器以上公寓的ELF-MF可以比同一建筑物中的其他公寓高5倍。这项新颖的研究设计旨在最大程度地纳入高度暴露的儿童,同时最大程度地减少选择偏差的可能性。
    方法:我们使用在5个国家收集的基于登记的匹配病例对照数据,评估了住宅靠近变压器与儿童白血病风险之间的关联。曝光是基于受试者公寓相对于变压器的位置,编码为高(高于或靠近变压器),中间(与高级公寓相同的楼层),或未暴露(其他公寓)。使用条件逻辑和混合逻辑回归估计儿童白血病的相对风险(RR),对病例对照集具有随机效应。
    结果:各国的数据汇集产生了16例中度病例和3例高度暴露病例。在条件逻辑模型中,中度暴露的RRs为1.0(95%CI:0.5,1.9),高暴露的RRs为1.1(95%CI:0.3,3.8)。在混合逻辑模型中,中间的RRs为1.4(95%CI:0.8,2.5),高的RRs为1.3(95%CI:0.4,4.4)。最具影响力国家的数据显示,中度(8例)和高度(2例)暴露的RR分别为1.1(95%CI:0.5,2.4)和1.7(95%CI:0.4,7.2)。
    结论:总体而言,风险升高的证据很弱。然而,小的数字和宽的置信区间排除了强有力的结论,不能排除在电力线研究中观察到的量级的风险.
    OBJECTIVE: New epidemiologic approaches are needed to reduce the scientific uncertainty surrounding the association between extremely low frequency magnetic fields (ELF-MF) and childhood leukemia. While most previous studies focused on power lines, the Transformer Exposure study sought to assess this association using a multi-country study of children who had lived in buildings with built-in electrical transformers. ELF-MF in apartments above built-in transformers can be 5 times higher than in other apartments in the same building. This novel study design aimed to maximize the inclusion of highly exposed children while minimising the potential for selection bias.
    METHODS: We assessed associations between residential proximity to transformers and risk of childhood leukemia using registry based matched case-control data collected in five countries. Exposure was based on the location of the subject\'s apartment relative to the transformer, coded as high (above or adjacent to transformer), intermediate (same floor as apartments in high category), or unexposed (other apartments). Relative risk (RR) for childhood leukemia was estimated using conditional logistic and mixed logistic regression with a random effect for case-control set.
    RESULTS: Data pooling across countries yielded 16 intermediate and 3 highly exposed cases. RRs were 1.0 (95% CI: 0.5, 1.9) for intermediate and 1.1 (95% CI: 0.3, 3.8) for high exposure in the conditional logistic model. In the mixed logistic model, RRs were 1.4 (95% CI: 0.8, 2.5) for intermediate and 1.3 (95% CI: 0.4, 4.4) for high. Data of the most influential country showed RRs of 1.1 (95% CI: 0.5, 2.4) and 1.7 (95% CI: 0.4, 7.2) for intermediate (8 cases) and high (2 cases) exposure.
    CONCLUSIONS: Overall, evidence for an elevated risk was weak. However, small numbers and wide confidence intervals preclude strong conclusions and a risk of the magnitude observed in power line studies cannot be excluded.
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  • 文章类型: Journal Article
    为了监测第一例与COVID-19相关的住院患者的相对疫苗有效性(rVE),第二次和第三次COVID-19加强(与完全初次疫苗接种相比),我们使用8个欧洲国家的电子健康登记处构建的回顾性队列进行每月Cox回归模型,2021年10月-2023年7月。给药后12周内,每个助推器显示高rVE(第二和第三助推器≥70%).然而,截至2023年7月,大部分相对收益已经减弱,特别是在≥80岁的人中,虽然在65-79岁的人群中仍然存在一些保护措施。
    To monitor relative vaccine effectiveness (rVE) against COVID-19-related hospitalisation of the first, second and third COVID-19 booster (vs complete primary vaccination), we performed monthly Cox regression models using retrospective cohorts constructed from electronic health registries in eight European countries, October 2021-July 2023. Within 12 weeks of administration, each booster showed high rVE (≥ 70% for second and third boosters). However, as of July 2023, most of the relative benefit has waned, particularly in persons ≥ 80-years-old, while some protection remained in 65-79-year-olds.
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  • 文章类型: Journal Article
    虚弱已被认为是老年人中日益严重的问题,最近的证据表明这种情况预示着一些与健康相关的问题,包括认知能力下降.这项工作的目的是确定虚弱是否与来自不同国家的老年人的认知能力下降有关。
    我们分析了全球老龄化和成人健康研究(SAGE)的基线,其中包括六个国家(加纳,南非,墨西哥,中国,俄罗斯,和印度)。横截面分析用于评估脆弱与临床脆弱量表决策树的关系,而认知下降是使用SAGE中使用的标准化测试分数进行评估的。
    总共包括30,674名50岁或以上的参与者。虚弱水平与认知表现之间存在关联。例如,女性在虚弱水平和认知得分之间存在反比关系,即使将稳健类别与脆弱级别2(RRR=0.85;p=0.41)进行比较,尽管相对风险在3级显著降低(RRR=0.66;p=0.03)。当控制年龄时,随着认知能力的提高,衰弱4-7级之间的相对风险显著降低(RRR=0.46,RRR=0.52,RRR=0.44,RRR=0.32;p<0.001).
    我们的结果表明,以新颖的方式测量的脆弱水平之间存在关联,以及不同文化背景下的认知能力下降。
    UNASSIGNED: Frailty has been recognized as a growing issue in older adults, with recent evidence showing that this condition heralds several health-related problems, including cognitive decline. The objective of this work is to determine if frailty is associated with cognitive decline among older adults from different countries.
    UNASSIGNED: We analyzed the baseline the Study on Global Ageing and Adult Health (SAGE), that includes six countries (Ghana, South Africa, Mexico, China, Russia, and India). A cross-section analysis was used to assess how Frailty was related with the Clinical Frailty Scale decision tree, while cognitive decline was evaluated using standardized scores of tests used in SAGE.
    UNASSIGNED: A total of 30,674 participants aged 50 years or older were included. There was an association between frailty levels and cognitive performance. For example, women had an inverse relationship between frailty levels and cognitive scores, even when comparing robust category with frailty level 2 (RRR = 0.85; p = 0.41), although the relative risks decrease significantly at level 3 (RRR = 0.66; p = 0.03). When controlling for age, the relative risks between frailty levels 4 to 7 significantly decreased as cognitive performance increased (RRR = 0.46, RRR = 0.52, RRR = 0.44, RRR = 0.32; p < 0.001).
    UNASSIGNED: Our results show an association between frailty levels measured in a novel way, and cognitive decline across different cultural settings.
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  • 文章类型: Journal Article
    如何减少对COVID-19疫苗的误解?我们介绍了在10个国家(N=10600)同时对YouGov样本进行的实验结果,这表明事实更正会不断减少对疫苗的错误信念。根据这10个国家的结果,我们发现,在4点量表上,暴露于校正会使信念准确度提高0.16,而暴露于错误信息会在相同的尺度上使信念准确性降低0.09。我们无法找到证据证明错误信息或事实更正会影响接种疫苗的意图或疫苗态度。我们对效应持续时间的发现不太具有决定性;当我们在两周后重新联系参与者时,我们观察到39%的初始精度提高,然而,这一结果略低于具有统计学意义的常规阈值(p=0.06).一起来看,我们的结果说明了事实校正的可能性和局限性。来自10个高度多样化人群的证据表明,暴露于事实信息会减少对疫苗虚假的信念,但对随后的行为和态度影响很小。
    What can be done to reduce misperceptions about COVID-19 vaccines? We present results from experiments conducted simultaneously on YouGov samples in 10 countries (N = 10 600), which reveal that factual corrections consistently reduce false beliefs about vaccines. With results from these 10 countries, we find that exposure to corrections increases belief accuracy by 0.16 on a 4-point scale, while exposure to misinformation decreases belief accuracy by 0.09 on the same scale. We are unable to find evidence that either misinformation or factual corrections affect intent to vaccinate or vaccine attitudes. Our findings on effect duration are less conclusive; when we recontacted participants two weeks later, we observed 39% of the initial accuracy increase, yet this result narrowly misses conventional thresholds of statistical significance (p = 0.06). Taken together, our results illustrate both the possibilities and limitations of factual corrections. Evidence from 10 highly diverse populations shows that exposure to factual information reduces belief in falsehoods about vaccines, but has minimal influence on subsequent behaviours and attitudes.
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  • 文章类型: Journal Article
    背景:本研究旨在对整个非洲的医疗保健结构的共性和差异进行结构化描述,为营养和营养干预的健康技术评估(HTA)建立可靠的基础。纳入了参与国一般人群的当前营养状况排名,以更好地了解影响医院营养不良(HMN)的因素,这将为未来的多国研究提供信息。
    方法:在十个非洲国家中分发了关于卫生系统结构的调查表。其中包括询问使用HTA原则评估营养护理的驱动因素或障碍的小节。营养不良数据的分析和排名是基于全球饥饿指数报告的数据和世界银行使用的两个贫困指标。
    结果:确定并描述了每个国家的卫生系统结构,然而,由于大多数国家缺乏足够深入的知识和技能,关于HTA的问题并不总是可以分析。一些国家的早期经验表明,非洲国家在根据不同的国家医疗保健背景和健康的社会决定因素加强和实施HTA的能力方面有一条可以想象的道路。
    结论:与营养护理相关的问题是被调查国家的主要优先事项之一。未来的HMN多国研究将为低成本一级预防方向的潜力提供宝贵的见解。
    BACKGROUND: This study aimed to provide a structured description of the commonalities and differences in healthcare structures across Africa to establish a reliable basis for the health technology assessment (HTA) of nutrition and nutrition interventions. A ranking of current nutrition conditions in the general population of the participating countries was included to gain a better understanding of the factors influencing hospital malnutrition (HMN), which will inform future multi-country research.
    METHODS: A questionnaire on the structure of the health systems was distributed among ten African countries. Subsections were included that inquired about the drivers or barriers to using principles of HTA to assess nutritional care. Analysis and ranking of malnutrition data were based on data from the Global Hunger Index report and two poverty indicators used by the World Bank.
    RESULTS: The health system structure of each country was identified and described, whereas questions about HTA could not always be analyzed due to a lack of adequate in-depth knowledge and skills in most countries. Early experience from some countries demonstrates a conceivable route ahead for African countries in strengthening the capacity for and implementing HTA in accordance with distinct national healthcare contexts and social determinants of health.
    CONCLUSIONS: Problems related to nutritional care represent one of the major priorities in the surveyed countries. A future HMN multi-country study will provide valuable insight into the potential of low-cost primary prevention orientations.
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  • 文章类型: Journal Article
    背景:在过去的几十年中,巨大儿在全球范围内迅速增加,对健康有巨大影响。然而,PM2.5和极端高温(EHT)对巨大儿的影响被忽略。
    目的:本研究旨在探讨母体暴露于EHT之间的关系。根据非洲14个国家的第七次人口和健康调查(DHS),PM2.5和巨大儿。
    方法:该研究包括了106382名新生儿和产妇的详细人口统计信息。卫星反演模型估计每月平均PM2.5和平均地表温度为2m(SMT2m)。巨大儿定义为出生体重≥4000g。我们使用Cox比例风险回归模型来估计PM2.5之间的关联。EHT和巨大儿。我们进一步探讨了不同孕期暴露于EHT和PM2.5对巨大儿的易感性,并使用有限的三次样条函数绘制了PM2.5和巨大儿风险之间的暴露反应曲线。此外,利用Interplot模型研究了EHT与PM2.5对巨大儿的相互作用。最后,通过分层分析了一些潜在的混杂因素.
    结果:EHT,PM2.5和巨大儿,随着PM2.5浓度的增加,巨大儿的风险没有明确的阈值。同时,EHT和PM2.5对妊娠中期/晚期和早期/中期巨大儿的影响更大,分别。EHT和PM2.5对巨大儿具有显著的交互作用。
    结论:母亲暴露于EHT,怀孕期间的PM2.5与非洲巨大儿风险增加有关。
    Macrosomia has increased rapidly worldwide in the past few decades, with a huge impact on health. However, the effect of PM2.5 and extreme high-temperature (EHT) on macrosomia has been ignored.
    This study aimed to explore the association between maternal exposure to EHT, PM2.5 and macrosomia based on the Seventh Demographic and Health Survey (DHS) in 14 countries of Africa.
    The study included detailed demographic information on 106 382 births and maternal. Satellite inversion models estimated monthly mean PM2.5 and mean surface temperature of 2 m (SMT2m ). Macrosomia was defined as the birth weight ≥ 4000 g. We used a Cox proportional risk regression model to estimate the association between PM2.5 , EHT and macrosomia. We further explored the susceptibility of exposure to EHT and PM2.5 at different pregnancy periods to macrosomia, and plotted the expose-response curve between PM2.5 and macrosomia risk using a restricted cubic spline function. In addition, the Interplot model was used to investigate the interaction between EHT and PM2.5 on macrosomia. Finally, some potential confounding factors were analysed by stratification.
    There was the positive association between EHT, PM2.5 and macrosomia, and the risk of macrosomia with the increase in concentrations of PM2.5 without clear threshold. Meanwhile, EHT and PM2.5 had a higher effect on macrosomia in middle/later and early/middle stages of pregnancy, respectively. There was a significant interaction between EHT and PM2.5 on macrosomia.
    Maternal exposure to EHT, PM2.5 during pregnancy was associated with an increased risk of macrosomia in Africa.
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  • 文章类型: Journal Article
    BACKGROUND: Vaccines are effective and reliable public health interventions against viral outbreaks and pandemics. However, hesitancy regarding the Coronavirus disease (COVID-19) vaccine is evident worldwide. Therefore, understanding vaccination-related behavior is critical in expanding the vaccine coverage to flatten the infection curve. This study explores the public perception regarding COVID-19 vaccination and identifies factors associated with vaccine hesitancy among the general adult populations in six Southeast Asian countries.
    METHODS: Using a snowball sampling approach, we conducted a descriptive cross-sectional study among 5260 participants in Indonesia, Malaysia, Myanmar, Philippines, Thailand, and Vietnam between February and May 2021. Binary logistic regression analysis with a backward conditional approach was applied to identify factors associated with COVID-19 vaccine hesitancy.
    RESULTS: Of the total, 50.6% were female, and the median age was 30 years (range: 15-83 years). The majority of the participants believed that vaccination effectively prevents and controls COVID-19 (81.2%), and 84.0% would accept COVID-19 vaccines when they become available. They agreed that health providers\' advice (83.0%), vaccination convenience (75.6%), and vaccine costs (62.8%) are essential for people to decide whether to accept COVID-19 vaccines. About half (49.3%) expressed their hesitancy to receive the COVID-19 vaccines. After adjustment for other covariates, COVID-19 vaccine hesitancy was significantly associated with age, residential area, education levels, employment status, and family economic status. Participants from Indonesia, Myanmar, Thailand, and Vietnam were significantly more likely to express hesitancy in receiving COVID-19 vaccines than those from Philippines.
    CONCLUSIONS: In general, participants in this multi-country study showed their optimistic perception of COVID-19 vaccines\' effectiveness and willingness to receive them. However, about half of them still expressed their hesitancy in getting vaccinated. The hesitation was associated with several socioeconomic factors and varied by country. Therefore, COVID-19 vaccination programs should consider these factors essential for increasing vaccine uptake in the populations.
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  • 文章类型: Journal Article
    Suicide is the fourth leading cause of death worldwide in young people aged 15-19 years. However, little is known about the correlates of multiple suicide attempts in adolescents, especially from a global perspective. Therefore, the aim of the present study was to investigate the association of putative physical, behavioral, and social correlates with multiple suicide attempts among adolescents aged 12-15 years from 61 countries. Data from the Global school-based Student Health Survey (2009-2017) were analyzed. Multiple suicide attempts was classified as having attempted suicide at least twice in the past 12 months. Multivariable logistic regression analyses were conducted to assess the potential correlates. Data on 162,994 adolescents [mean (SD) age 13.8 (0.9) years; 50.8% boys] were analyzed. The overall prevalence of multiple suicide attempts was 4.4% [range 1.2% (Laos) to 13.8% (Ghana)]. Among those who had attempted suicide at least once in the past 12 months, in the overall sample, food insecurity, smoking, alcohol consumption, cannabis use, amphetamine use, sedentary behavior, sexual intercourse, sleep problems, loneliness, no close friends, and bullying victimization were all independently associated with higher odds for multiple suicide attempts although some regional differences were observed. Our study results indicate potential target factors that could be addressed amongst those who had attempted suicide in the past to reduce future suicide attempts and possibly completed suicides. Furthermore, it is possible that region-specific interventions are necessary.
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