炎症性肠病(IBD)是一种终生疾病,需要经常评估以指导治疗并预防耀斑或进展。临床医生可以使用多种工具来监测疾病活动;但是,缺乏数据来告知患者最可接受的监测工具。这篇综述旨在描述患者偏好的现有证据,满意,成人IBD患者可用监测工具的耐受性和/或可接受性。
■Embase,Medline,从1980年1月至2019年4月,对CochraneCentralandClinicalTrials.gov进行了搜索,以了解所有研究类型,这些研究类型报告了在监测工具上确诊为IBD的成年人的观点。两个或更多的工具进行比较。提供了带有摘要和描述性数据的结果指标。
■在10项评估1846名参与者的研究中,监测工具包括静脉穿刺,大便收集,胃肠超声,计算机断层扫描,磁共振成像,无线胶囊内窥镜检查,钡随访和内窥镜检查。结果领域是患者满意度,监测工具的可接受性和患者偏好。在9项研究中,非侵入性检查优于内窥镜检查。评估时,与内窥镜检查或其他成像方式相比,胃肠道超声始终具有更高的可接受性和满意度。
■患有IBD的成年人首选非侵入性检查,尤其是胃肠超声,与用于监测疾病活动的内窥镜检查相比。在评估疾病活动时,在选择监测工具时,应考虑患者的感知。进一步的研究应解决是否采用被认为更可接受的监测方法患者的结果更大的满意度,依从性和最终更有益的临床结果。
UNASSIGNED: Inflammatory bowel disease (IBD) is a lifelong disease requiring frequent assessment to guide treatment and prevent flares or progression. Multiple tools are available for clinicians to monitor disease activity; however, there are a paucity of data to inform which monitoring tools are most acceptable to patients. The review aims to describe the available evidence for patient preference, satisfaction, tolerance and/or acceptability of the available monitoring tools in adults with IBD.
UNASSIGNED: Embase, Medline, Cochrane Central and Clinical Trials.gov were searched from January 1980 to April 2019 for all study types reporting on the perspectives of adults with confirmed IBD on monitoring tools, where two or more tools were compared. Outcome measures with summary and descriptive data were presented.
UNASSIGNED: In 10 studies evaluating 1846 participants, monitoring tools included venipuncture, stool collection, gastrointestinal ultrasound, computed tomography, magnetic resonance imaging, wireless capsule endoscopy, barium follow-through and endoscopy. Outcome domains were patient satisfaction, acceptability of monitoring tool and patient preference. Noninvasive investigations were preferable to endoscopy in nine studies. When assessed, gastrointestinal ultrasound was consistently associated with greater acceptability and satisfaction compared with endoscopy or other imaging modalities.
UNASSIGNED: Adults with IBD preferred noninvasive investigations, in particular gastrointestinal ultrasound, as compared to endoscopy for monitoring disease activity. When assessing disease activity, patient perceptions should be considered in the selection of monitoring tools. Further research should address whether adpoting monitoring approaches considered more acceptable to patients results in greater satisfaction, adherence and ultimately more beneficial clinical outcomes.